| MUSICAL THEATER CENTER | Mount Pleasant | A65 Arts, Culture & Humanities | $226k | 0 |
| OCAB COMMUNITY DEVELOPMENT CORPORATION | Bamberg | — | $226k | 0 |
| Chapin Community Theatre Inc | Chapin | A61 Arts, Culture & Humanities | $225k | 6 |
| THE GLORIA AND JOSEPH BAUER FOUNDATION | Johns Island | X99 Religion-Related | $225k | 0 |
| Suzuki Academy of Columbia | Columbia | B28 Education | $225k | 1 |
| NEWBERRY COUNTY HOSPITAL FOUNDATION INC | Newberry | E122 Health Care | $225k | 1 |
| The Sophia Institute | Charleston | P50 Human Services | $225k | 1 |
| NURSES WITH PURPOSE INC | Columbis | P20 Human Services | $224k | 0 |
| BEN'S FRIENDS | Charleston | F21 Mental Health & Crisis Intervention | $224k | 1 |
| HANDS OF HOPE | North Augusta | Q33 International, Foreign Affairs & National Security | $224k | 2 |
| New Hope Equine | Aiken | D20 Animal-Related | $224k | 0 |
| NOBLE TREE FOUNDATION ORG | Spartanburg | C30 Environment | $224k | 0 |
| SOUTHERN PALMETTO REGIONAL CHAMBER OF COMMERCE | Barnwell | — | $224k | 0 |
| FOR THE LOVE OF A PAW | Elloree | D20 Animal-Related | $223k | 0 |
| Richardson Rescue | York | D20 Animal-Related | $223k | 2 |
| VETERINARY LEADERSHIP INSTITUTE INC | Myrtle Beach | B99 Education | $223k | 0 |
| POINSETT HOUSE SENIOR HOUSING CORPORATION | Spartanburg | L21 Housing & Shelter | $223k | 1 |
| THE MCALISTER FOUNDATION | Laurens | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $223k | 3 |
| ARTISTS FOR AFRICA INC | Columbia | A20 Arts, Culture & Humanities | $223k | 0 |
| GREATER OCONEE COUNTY CHAMBER OF COMMERCE | Seneca | — | $223k | 1 |
| CHURCH PLANTING INTERNATIONAL | Fort Mill | — | $223k | 2 |
| ALLEGIANCE HOME CARE INC | Lexington | E92 Health Care | $223k | 1 |
| GOUCHER-WHITE PLAINS VOLUNTEER FIRE | Gaffney | M24Z Public Safety, Disaster Preparedness & Relief | $223k | 0 |
| CROSSCAMPUS INTERNATIONAL INC | Spartanburg | Q22 International, Foreign Affairs & National Security | $222k | 1 |
| Falatok Foundation | Spartanburg | T11 Philanthropy, Voluntarism & Grantmaking Foundations | $222k | 0 |
| AMERICAN FEDERATION OF GOVERNMENT EMPLOYEES LOCAL 1915 | Columbia | — | $222k | 5 |
| GRACE IMPACT DEVELOPMENT CENTER INC | Moncks Corner | P50 Human Services | $222k | 0 |
| KAPPA DELTA SORORITY - ZETA SIGMA CHAPTER | Charleston | N50 Recreation & Sports | $222k | 0 |
| CHI OMEGA FRATERNITY | Charleston | — | $222k | 0 |
| IT-OLOGY | Columbia | B99 Education | $222k | 0 |
| SHARE OUR SUZY LOWCOUNTRY | Mount Pleasant | P20 Human Services | $222k | 0 |
| ASIAN AMERICAN STORE OWNERS ASSOCIATION OF SOUTH CAROLINA INC | Orangeburg | P20 Human Services | $222k | 0 |
| Fort Mill Economic Partners | Fort Mill | A82 Arts, Culture & Humanities | $222k | 1 |
| CHRISTIAN CHAPMAN MINISTRIES | Okatie | — | $222k | 0 |
| SOUTH CAROLINA FIRST STEPS TO SCHOOL READINESS - ALLENDALE COUNTY | Greenwood | B012 Education | $222k | 1 |
| THE VILLAGE REPERTORY COMPANY | Charleston | A65 Arts, Culture & Humanities | $222k | 0 |
| SC ASSOCIATION OF REGISTRATION AND ELECTION OFFICIALS INC | N Charleston | S41 Community Improvement & Capacity Building | $221k | 0 |
| WIDEMAN DAVIS DANCE OF NEW YORK INC | Columbia | A62 Arts, Culture & Humanities | $221k | 0 |
| O PERRY EARLE JR & LOUISE JORDAN EARLE F FOUNDATION C/O O PERRY EARLE III TRUSTE | Fountain Inn | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $221k | 0 |
| SUNSET CAY SOCIAL CLUB | Charleston | N50 Recreation & Sports | $221k | 3 |
| AIKEN AFRICA INTERNATIONAL MISSION | Aiken | X01 Religion-Related | $221k | 0 |
| LAURENS COUNTY HUMANE SOCIETY | Clinton | S80 Community Improvement & Capacity Building | $221k | 0 |
| RMS FAMILY FOUNDATION INC | Myrtle Beach | G12 Diseases, Disorders & Medical Disciplines | $220k | 0 |
| GREATER BLUFFTON CHAMBER & CONVENTION VISITORS BUREAU INC | Bluffton | — | $220k | 1 |
| GAMECOCK FOUNDATION | Columbia | P60 Human Services | $220k | 0 |
| THE FRIENDS OF HUNTING ISLAND STATE PARK INC | Beaufort | C30Z Environment | $220k | 0 |
| Legacy Affordable Housing Trust | Greenville | L20 Housing & Shelter | $220k | 1 |
| GREATER ANDERSON MUSICAL ARTS CONSORTIUM | Anderson | A68L Arts, Culture & Humanities | $220k | 0 |
| Horry-Conway County Farm Bureau | Conway | — | $220k | 0 |
| ZAHN FOUNDATION INC | Fair Play | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $219k | 0 |
