| NASHVILLE HUMANE ASSOCIATION | Nashville | D200 Animal-Related | $4.3M | 2 |
| KNOXVILLE AREA URBAN LEAGUE INC | Knoxville | P22Z Human Services | $4.3M | 3 |
| GIVING FORWARD INC | Hendersonville | T11 Philanthropy, Voluntarism & Grantmaking Foundations | $4.3M | 0 |
| MARYVILLE CHRISTAN SCHOOL | Maryville | — | $4.3M | 0 |
| COMPETENCY-BASED EDUCATION NETWORK | Franklin | B01 Education | $4.3M | 4 |
| ASPIRE CLARKSVILLE | Clarksville | S30 Community Improvement & Capacity Building | $4.3M | 0 |
| DEER RUN RETREAT CENTER | Thompsons Station | X20 Religion-Related | $4.3M | 3 |
| JESUS FOR ASIA INC | Collegedale | X20 Religion-Related | $4.3M | 1 |
| THE STORE INC | Nashville | P20 Human Services | $4.3M | 2 |
| THE NURSING CENTER AT LITTLE CREEK | Knoxville | F31Z Mental Health & Crisis Intervention | $4.3M | 4 |
| KNOWLEDGE QUEST INC | Memphis | O50 Youth Development | $4.3M | 1 |
| VOLUNTEER FIREFIGHTER ALLIANCE INC | White Pine | M99 Public Safety, Disaster Preparedness & Relief | $4.3M | 4 |
| THE BOYD FOUNDATION | Knoxville | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $4.3M | 1 |
| INTERNATIONAL BOARD OF JEWISH MISSIONS | Hixson | X90Z Religion-Related | $4.3M | 1 |
| AMERICAN GI FORUM CASA DE ESPERANZA INC | Memphis | — | $4.3M | 0 |
| LEGACYTREE FOUNDATION | Spring Hill | X20 Religion-Related | $4.2M | 2 |
| TENNESSEE HEALTH CARE ASSOCIATION | Brentwood | — | $4.2M | 7 |
| INTERNATIONAL BROTHERHOOD OF ELECTR | Memphis | — | $4.2M | 11 |
| THE CLAYTON FOUNDATION | Knoxville | T11 Philanthropy, Voluntarism & Grantmaking Foundations | $4.2M | 0 |
| Nashville Wine Auction | Nashville | H123 Medical Research | $4.2M | 1 |
| GREATER NASHVILLE ASSOCIATION OF REALTORS INC | Nashville | — | $4.2M | 3 |
| CLARKSVILLE-MONTGOMERY COUNTY ECONOMIC | Clarksville | — | $4.2M | 2 |
| MISSION OF HOPE | Knoxville | P600 Human Services | $4.2M | 1 |
| RUTHERFORD COUNTY CHAMBER OF COMMERCE | Murfreesboro | — | $4.2M | 4 |
| THE FLORENCE CRITTENTON AGENCY INC | Knoxville | — | $4.2M | 3 |
| UPPER CUMBERLAND LOCAL WORKFORCE | Cookeville | J20 Employment | $4.2M | 2 |
| INTERNATIONAL ASSOCIATION OF MACHINISTS & AEROSPACE WORKERS | Clarksville | — | $4.2M | 6 |
| REGAL FOUNDATION | Knoxville | T21 Philanthropy, Voluntarism & Grantmaking Foundations | $4.2M | 0 |
| AUSTIN HATCHER FOUNDATION FOR PEDIATRIC | Chattanooga | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $4.2M | 2 |
| NATIONAL HARDWOOD LUMBER ASSOCIATION | Memphis | — | $4.2M | 5 |
| COMMUNITY FOUNDATION OF CLEVELAND | Cleveland | S11 Community Improvement & Capacity Building | $4.2M | 1 |
| Intercollegiate Center For Classical Studies | Brentwood | B42 Education | $4.2M | 2 |
| GIRL SCOUTS HEART OF THE SOUTH | Memphis | O42 Youth Development | $4.2M | 1 |
| VISIBLE MUSIC COLLEGE | Memphis | B28 Education | $4.2M | 0 |
| OPERATING ENGINEERS 474 | Goodlettsville | — | $4.1M | 0 |
| LOUISIANA LABORERS HEALTH & WELFARE FUND | Goodlettsville | — | $4.1M | 0 |
| River's Edge Christian Academy | Knoxville | B20 Education | $4.1M | 1 |
| NORTHSIDE NEIGHBORHOOD HOUSE | Chattanooga | P200 Human Services | $4.1M | 1 |
| Urban Renaissance Partners Inc | Memphis | L20 Housing & Shelter | $4.1M | 0 |
| YOUTH PROGRAMS INC | Memphis | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $4.1M | 0 |
| TENNESSEE VALLEY PAINTERS HEALTH | Goodlettsville | — | $4.1M | 0 |
| BIRTHPLACE OF COUNTRY MUSIC INC | Bristol | A68 Arts, Culture & Humanities | $4.1M | 2 |
| R BRAD MARTIN FAMILY FOUNDATION | Chattanooga | T22Z Philanthropy, Voluntarism & Grantmaking Foundations | $4.1M | 0 |
| UNITED HOUSING INC | Memphis | L20 Housing & Shelter | $4.1M | 1 |
| GREAT SMOKY MOUNTAIN COUNCIL 557 | Knoxville | O410 Youth Development | $4.1M | 1 |
| UNITED FOOD & COMMERCIAL WORKERS | Hermitage | — | $4.1M | 15 |
| KNOX HOUSING PARTNERSHIP INC | Knoxville | L20Z Housing & Shelter | $4.1M | 1 |
| Both Hands Foundation | Brentwood | P99 Human Services | $4.1M | 2 |
| SOULSVILLE FOUNDATION | Memphis | A540 Arts, Culture & Humanities | $4M | 4 |
| MEMPHIS MUSEUMS OF SCIENCE & HISTORY | Memphis | A120 Arts, Culture & Humanities | $4M | 1 |
