| RENY CHARITABLE FOUNDATION | Newcastle | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $512k | 0 |
| HEART OF BIDDEFORD | Biddeford | S20 Community Improvement & Capacity Building | $511k | 1 |
| MAYO STREET ARTS | Portland | P20 Human Services | $509k | 1 |
| NORTHEAST HARBOR FLEET | Northeast Harbor | — | $509k | 0 |
| NORTH BERWICK FOOD PANTRY | North Berwick | K31 Food, Agriculture & Nutrition | $508k | 0 |
| ELEPHANT ROCK FUND | Wayne | T11 Philanthropy, Voluntarism & Grantmaking Foundations | $508k | 0 |
| WISCASSET PUBLIC LIBRARY | Wiscasset | B71Z Education | $507k | 1 |
| LAKE STEWARDS OF MAINE - MAINE VOLUNTEER LAKE MONITORING PROGRAM | Auburn | C320 Environment | $506k | 1 |
| SANFORD MAINE ELKS LODGE NO 1470 | Sanford | — | $506k | 2 |
| Safe Abortions For Everyone | Portland | — | $506k | 1 |
| HABITAT FOR HUMANITY 7 RIVERS MAINE 7 RIVERS MAINE | Topsham | — | $506k | 1 |
| GREATER PORTLAND FAMILY PROMISE | Portland | P85 Human Services | $505k | 1 |
| FRIENDS OF WILSON POND AREA INC | Greenville | — | $505k | 0 |
| Pleasant River Ambulance Service | Columbia | E62 Health Care | $504k | 0 |
| GREAT WORKS CREMATORY | North Berwick | — | $504k | 0 |
| PORTLAND LODGE NO 1310 LOYAL ORDER OF MOOSE | Scarborough | I60 Crime & Legal-Related | $503k | 1 |
| TRITON RESEARCH INSTITUTE | Friendship | U50 Science & Technology | $502k | 0 |
| AK HEALTH AND SOCIAL SERVICES | Lewiston | P20 Human Services | $501k | 1 |
| FRANKLIN COUNTY ANIMAL SHELTER | Farmington | D200 Animal-Related | $499k | 1 |
| SEEDMONEY | Scarborough | C40 Environment | $499k | 1 |
| HOSPICE VOLUNTEERS OF HANCOCK COUNTY | Ellsworth | — | $498k | 0 |
| LE CLUB FRANCAIS | Madawaska | B99 Education | $497k | 0 |
| CAMP CAPELLA INC | Holden | P82 Human Services | $497k | 1 |
| North Atlantic Arts Alliance | Hiram | A01 Arts, Culture & Humanities | $497k | 2 |
| MCARTHUR HOME FOR THE AGED PEOPLE | Biddeford | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $495k | 0 |
| NASSON CENTER REDEVELOPMENT INC | Springvale | N31 Recreation & Sports | $491k | 1 |
| BREAKING THE CYCLE | Millinocket | L99 Housing & Shelter | $490k | 2 |
| HIS HANDS SUPPORT MINISTRIES | Peru | X90 Religion-Related | $490k | 0 |
| AMERICAN ACADEMY OF PEDIATRICS MAINE CHAPTER INC | Manchester | G98 Diseases, Disorders & Medical Disciplines | $490k | 0 |
| NEW ENGLAND ARAB AMERICAN ORGANIZATION | Portland | P84 Human Services | $489k | 8 |
| THE ROBINSON FOUNDATION | Machiasport | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $488k | 0 |
| Harpswell News | Harpswell | A33 Arts, Culture & Humanities | $487k | 0 |
| Maine Climate Action Now | Augusta | C01 Environment | $486k | 3 |
| Maine Family Resource Center | Danforth | B90 Education | $485k | 0 |
| BOOTHBAY HARBOR MEMORIAL LIBRARY ASSOCIATION | Boothbay Harbor | B71Z Education | $485k | 1 |
| FRANCIS SMALL HERITAGE TRUST INC | Limerick | C340 Environment | $485k | 0 |
| VAUGHAN WOODS AND HISTORIC HOMESTEAD | Hallowell | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $485k | 1 |
| USM Student Senate | Portland | — | $485k | 7 |
| SCHOODIC ARTS FOR ALL | Winter Harbor | A200 Arts, Culture & Humanities | $485k | 0 |
| Youth Full Maine | Biddeford | K31 Food, Agriculture & Nutrition | $484k | 0 |
| THE WATERSHED COMMUNITY INSTITUTE | Lincolnville | — | $483k | 0 |
| Maine Woods Conservancy Inc | Sebec | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $483k | 0 |
| MAINE PRESERVATION | Yarmouth | A82Z Arts, Culture & Humanities | $482k | 1 |
| SHEEPSCOT VALLEY CHILDRENS HOUSE | Wiscasset | B21Z Education | $482k | 0 |
| Wild Seed Project | North Yarmouth | C40 Environment | $481k | 1 |
| Maine Philanthropy Center | Portland | B70 Education | $480k | 1 |
| WILLIAM & ADELINE PENFIELD JARVIS FOUNDATION | York Harbor | T20J Philanthropy, Voluntarism & Grantmaking Foundations | $479k | 0 |
| Southern Maine Community Recreation Center | Gorham | N31 Recreation & Sports | $479k | 1 |
| GARDINER LIBRARY ASSOCIATION | Gardiner | B70 Education | $479k | 0 |
| MAINE RESILIENCE BUILDING NETWORK | Manchester | B90 Education | $478k | 1 |
