| GATES FOUNDATION TRUST | Kirkland | WA | $10.2B | 0 |
| NATIONAL PHILANTHROPIC TRUST | Jenkintown | PA | $10B | 18 |
| DONOR ADVISED CHARITABLE GIVING INC | San Francisco | CA | $9.7B | 11 |
| BILL & MELINDA GATES FOUNDATION | Seattle | WA | $7.8B | 17 |
| GS DONOR ADVISED PHILANTHROPY FUND | New York | NY | $6.6B | 0 |
| VANGUARD CHARITABLE ENDOWMENT PROGRAM | Southeastern | PA | $4.6B | 9 |
| Michael & Susan Dell Foundation | Austin | TX | $4.3B | 1 |
| MORGAN STANLEY GLOBAL IMPACT FUNDING TRUST INC | Indianapolis | IN | $3.1B | 0 |
| A D F COMMUNITY OUTREACH FOUNDATION INC | Mechanicsville | MD | $2.7B | 0 |
| GORDON E AND BETTY I MOORE FOUNDATION | Palo Alto | CA | $2.7B | 3 |
| The Chicago Community Trust | Chicago | IL | $2.5B | 11 |
| NATL CHRISTIAN CHARITABLE FDN INC | Alpharetta | GA | $2.4B | 24 |
| GOOD VENTURES FOUNDATION | Palo Alto | CA | $2.2B | 0 |
| AMERICAN ONLINE GIVING FOUNDATION INC | Newark | DE | $2.1B | 0 |
| MERCK PATIENT ASSISTANCE PROGRAM INC | Rahway | NJ | $1.9B | 0 |
| KNIGHT FOUNDATION | Beaverton | OR | $1.7B | 0 |
| THE SUSAN THOMPSON BUFFETT FOUNDATION | Omaha | NE | $1.7B | 2 |
| BANK OF AMERICA CHARITABLE GIFT FD | Boston | MA | $1.7B | 1 |
| THE BLOOMBERG FAMILY FOUNDATION INC | New York | NY | $1.6B | 22 |
| Silicon Valley Community Foundation | Mountain View | CA | $1.6B | 11 |
| CHAN ZUCKERBERG INITIATIVE FOUNDATION | Palo Alto | CA | $1.5B | 0 |
| Renaissance Charitable Foundation Inc | Indianapolis | IN | $1.5B | 0 |
| AMERICAN ENDOWMENT FOUNDATION | Hudson | OH | $1.3B | 25 |
| VOLKSWAGENSTIFTUNG | Salt Lake City | UT | $1.2B | 1 |
| JEWISH COMMUNAL FUND | New York | NY | $1.1B | 11 |
| GlaxoSmithKline Patient Access | Philadelphia | PA | $1.1B | 0 |
| PIVOTAL PHILANTHROPIES PATHWAYS | Redmond | WA | $955.6M | 0 |
| CHARITIES AID FOUNDATION AMERICA | Alexandria | VA | $951.9M | 9 |
| JACK JOSEPH & MORTON MANDEL FOUNDATION | Cleveland | OH | $929.7M | 2 |
| JOHN D AND CATHERINE T MACARTHUR | Chicago | IL | $890.9M | 20 |
| Greater Horizons | Kansas City | MO | $890.4M | 2 |
| Walton Family Foundation Inc | Bentonville | AR | $872.2M | 3 |
| IMPACTASSETSINC | Bethesda | MD | $866.5M | 7 |
| THE ROBERT WOOD JOHNSON FOUNDATION | Princeton | NJ | $855.3M | 0 |
| FOUNDATION TO PROMOTE OPEN SOCIETY | New York | NY | $842.8M | 0 |
| DECHOMAI ASSET TRUST | Jacksonville | FL | $837M | 0 |
| Adam R Scripps Foundation | Ft Mitchell | KY | $767.2M | 1 |
| WALTER SCOTT FAMILY FOUNDATION | Omaha | NE | $762.5M | 3 |
| George Kaiser Family Foundation | Tulsa | OK | $736.2M | 8 |
| DALIO FOUNDATION INC | Westport | CT | $687.6M | 0 |
| LAURA AND JOHN ARNOLD FOUNDATION | Houston | TX | $687.3M | 0 |
| ROCKEFELLER PHILANTHROPY ADVISORS INC | New York | NY | $644.9M | 13 |
| DONORS FUND INC | Lakewood | NJ | $629M | 3 |
| THE WILLIAM & FLORA HEWLETT FOUNDATION | Menlo Park | CA | $602.1M | 3 |
| RAYMOND JAMES CHARITABLE ENDOWMENT FUND | St Petersburg | FL | $580.4M | 5 |
| THE BLACKBAUD GIVING FUND | Charleston Sc | SC | $561.4M | 2 |
| THE GEORGE AND BEVERLY RAWLINGS | LaGrange | KY | $543.7M | 0 |
| Lettie Pate Evans Foundation Inc | Atlanta | GA | $540.6M | 13 |
| WK Kellogg Foundation Trust - No 5315 | Battle Creek | MI | $540.1M | 5 |
| FOUNDATION FOR THE CAROLINAS | Charlotte | NC | $538M | 14 |
