| IGNITE ACHIEVEMENT ACADEMY INC | Indianapolis | B29 Education | $2.3M | 1 |
| NORTH AMERICAN INTERFRATERNITY CONFERENCE | Fishers | — | $2.3M | 4 |
| LIFE TREATMENT CENTERS INC | South Bend | F22Z Mental Health & Crisis Intervention | $2.3M | 1 |
| TIMMY GLOBAL HEALTH INC | Greenwood | E99 Health Care | $2.3M | 1 |
| CORAM DEO ACADEMY INC | Carmel | B20 Education | $2.3M | 0 |
| ST MARTINS HEALTHCARE INC | Garrett | E32 Health Care | $2.3M | 0 |
| INDIANAPOLIS LEGAL AID SOCIETY INC | Indianapolis | — | $2.3M | 0 |
| UNION HOSPITAL FOUNDATION INC | Terre Haute | E20J Health Care | $2.3M | 4 |
| GENNESARET FREE CLINIC INC | Indianapolis | E32Z Health Care | $2.2M | 1 |
| SOUTH LAWRENCE UTILITIES INC | Mitchell | — | $2.2M | 0 |
| Indiana Philanthropy Alliance Foundation Inc | Indianapolis | — | $2.2M | 1 |
| CENTER OF IMAGINATION CHILDCARE MINISTRIES INC | Indianapolis | B21 Education | $2.2M | 0 |
| WILLIAM E SCHMIDT FOUNDATION INC | Evansville | B28 Education | $2.2M | 6 |
| Life Centers Inc | Indianapolis | E400 Health Care | $2.2M | 1 |
| HORIZON INTERNATIONAL INC | Anderson | Q33 International, Foreign Affairs & National Security | $2.2M | 4 |
| WELLFIELD BOTANIC GARDENS INC | Elkhart | C41 Environment | $2.2M | 1 |
| Barbara B Jordan YMCA Inc | Martinsville | P27Z Human Services | $2.2M | 1 |
| COMMUNITY COORDINATED CHILD CARE OF ST JOSEPH COUNTY INCORPORATED | South Bend | P33Z Human Services | $2.2M | 1 |
| KIDS & CLAYS FOUNDATION | Michigan City | E12 Health Care | $2.2M | 1 |
| INDIANA BANKERS ASSOCIATION INC | Indianapolis | — | $2.2M | 5 |
| 2021 ALL-STAR INC | Indianapolis | S20 Community Improvement & Capacity Building | $2.2M | 0 |
| FUN TIMES CHILDCARE MINISTRY INC | Indianapolis | P33 Human Services | $2.2M | 2 |
| FRANKLIN COUNTY WATER ASSOC INC | Brookville In | — | $2.2M | 0 |
| LAPORTE MULTI-SCHOOL BUILDING CORP | LaPorte | — | $2.2M | 0 |
| BETTER BUSINESS BUREAU OF NORTHERN INDIANA INC | Fort Wayne | — | $2.2M | 1 |
| BAC LOCAL 4 OF INDIANA & KENTUCKY APPRENTICE AND TRAINING PROGRAM | Valparaiso | — | $2.2M | 0 |
| DISTRICT OF EVANSVILLE OF THE SOCIETY OF | Evansville | P29 Human Services | $2.2M | 0 |
| PET REFUGE INC | South Bend | D200 Animal-Related | $2.2M | 1 |
| ASSOCIATION FOR PROTESTANT REFORMED EDUCATION | Dyer | — | $2.2M | 0 |
| GEO ACADEMIES LOUISIANA HOLDINGS INC | Indianapolis | T02 Philanthropy, Voluntarism & Grantmaking Foundations | $2.2M | 0 |
| MCC RESOURCE CENTER INC | Goshen | — | $2.2M | 1 |
| NISOURCE UNION POST-65 RETIREE MEDICAL BENEFITS VEBA TRUST | Merrillville | Y43 Mutual & Membership Benefit | $2.2M | 0 |
| EATON EMERGENCY MEDICAL TECHNICIANS | Eaton | E62 Health Care | $2.2M | 0 |
| COVENANT CHRISTIAN SCHOOL | Mishawaka | — | $2.2M | 0 |
| UNITED WAY OF ALLEN COUNTY INC | Fort Wayne | T70Z Philanthropy, Voluntarism & Grantmaking Foundations | $2.2M | 3 |
| Midwest Academy Inc | Carmel | Z99Z Unknown | $2.2M | 3 |
| MARION-KOKOMO ELECTRICIAN JATC JOINT APPRENTICESHIP AND TRAINING | Kokomo | — | $2.2M | 3 |
| PURDUE CHRISTIAN CAMPUS HOUSE INC | West Lafayette | — | $2.2M | 1 |
| PARTNERS IN HOUSING DEVELOPMENT CORPORATION | Indianapolis | L20Z Housing & Shelter | $2.2M | 1 |
| EARLHAM CEMETERY INC | Richmond | — | $2.2M | 8 |
| YOUNG MENS CHRISTIAN ASSN OF MADISON COUNTY INC | Pendleton | P270 Human Services | $2.2M | 1 |
| YWCA OF EVANSVILLE INDIANA INC | Evansville | P27Z Human Services | $2.2M | 2 |
| INDIANA ASSOCIATION OF SCHOOL PRINCIPALS INC | Indianapolis | B25I Education | $2.2M | 1 |
| ASSOCIATION OF REAL ESTATE LICENSE LAW OFFICIALS | Fishers | — | $2.2M | 3 |
| THE NEUROSURGERY FOUNDATION AT GOODMAN CAMPBELL INC | Carmel | H96 Medical Research | $2.2M | 0 |
| YOUNG WOMENS CHRISTIAN ASSOCIATION OF GREATER LAFAYETTE | Lafayette | P27Z Human Services | $2.2M | 3 |
| CEDAR LAKE MINISTRIES | Cedar Lake | — | $2.2M | 0 |
| IRON WORKERS UNION LOCAL #22 APPRENTICE | Indianapolis | J22Z Employment | $2.2M | 4 |
| Dimension Mill INC | Bloomington | S20 Community Improvement & Capacity Building | $2.2M | 4 |
| NORTHEAST INDIANA FOUNDATION INC | Fort Wayne | S30 Community Improvement & Capacity Building | $2.2M | 6 |
