| HUB CITY ROOTS | Spartanburg | K40 Food, Agriculture & Nutrition | $499k | 0 |
| COASTAL SCHOOL MINISTRIES INC | Myrtle Beach | B99 Education | $499k | 0 |
| HORRY COUNTY FIRE RESCUE FOUNDATION | Murrells Inlet | M99 Public Safety, Disaster Preparedness & Relief | $499k | 0 |
| CHARLESTON AREA JUSTICE MINISTRY | North Charleston | S21 Community Improvement & Capacity Building | $498k | 2 |
| LESPRI MINISTRIES | Fort Mill | Q33 International, Foreign Affairs & National Security | $498k | 1 |
| Neighborhood Outreach Connection | Hilton Head | P80 Human Services | $497k | 5 |
| CHARLESTON ELECTRICAL TRAINING ALLIANCE 776 LOCAL UNION | North Charleston | J22 Employment | $497k | 0 |
| DANIEL MADISON FLOYD FOUNDATION | Florence | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $497k | 2 |
| MARION COUNTY COUNCIL ON AGING | Marion | P81Z Human Services | $496k | 1 |
| Baptist Healthcare System of South Carolina | Columbia | E210 Health Care | $495k | 0 |
| KYOCERA AVX Components Foundation | Fountain Inn | T21Z Philanthropy, Voluntarism & Grantmaking Foundations | $495k | 0 |
| CONSCIOUSNESS AND HEALING | Greenville | P05 Human Services | $494k | 1 |
| THE BEE CAUSE PROJECT INC | Isle Of Palms | B90 Education | $494k | 3 |
| WILDLIFE ACTION INC | Mullins | D013 Animal-Related | $493k | 0 |
| WILLIAM ENSTON HOME CO PARK SMITH | Charleston | L22Z Housing & Shelter | $492k | 1 |
| HOUSE OF HOPE INTERNATIONAL | Fountain Inn | M20 Public Safety, Disaster Preparedness & Relief | $492k | 1 |
| THE CHANGE CENTER INC | North Myrtle Beach | S20 Community Improvement & Capacity Building | $492k | 1 |
| SAMARITAN HEALTH CLINIC OF PICKENS COUNTY | Easley | — | $491k | 3 |
| WOUNDED NATUREORG | Mount Pleasant | C50 Environment | $490k | 0 |
| Baskervill Outreach Inc | Pawleys Island | L21Z Housing & Shelter | $490k | 0 |
| FOOTHILLS CHRISTIAN SCHOOL | Westminster | — | $490k | 0 |
| LAKE BOWEN CHILD DEVELOPMENT CENTER | Inman | P33 Human Services | $490k | 1 |
| DORCHESTER ECONOMIC DEVELOPMENT CORPORAT | Summerville | S30 Community Improvement & Capacity Building | $489k | 0 |
| JOSEPH PAUL APARTMENTS INC | West Columbia | — | $489k | 0 |
| AFRICAN CHRISTIANS FELLOWSHIP INT'L | Lancaster | X21 Religion-Related | $489k | 2 |
| HAGOOD MILL FOUNDATION | Pickens | A20 Arts, Culture & Humanities | $489k | 1 |
| KELLYS KITCHEN | St Helena Island | K99 Food, Agriculture & Nutrition | $488k | 0 |
| ANIMAL HELPERS RETAIL RESALE STORE | Charleston | D12 Animal-Related | $488k | 1 |
| Rock Hill School District Foundation | Rock Hill | — | $488k | 0 |
| G R A S P | Great Falls | X90 Religion-Related | $487k | 1 |
| TRUSTEES UW OF ALIDA HARPER FOWLKES | Columbia | T90Z Philanthropy, Voluntarism & Grantmaking Foundations | $487k | 0 |
| BULL SWAMP RURAL WATER COMPANY INC | Orangeburg | — | $486k | 0 |
| CITY OF ANDERSON PUBLIC FACILITIES | Anderson | W22 Public & Societal Benefit | $485k | 3 |
| GREATER GREENVILLE HOCKEY | Greer | N68 Recreation & Sports | $483k | 0 |
| HELEN WADE GREENE CHARITABLE TRUST GREEN100 | Fort Mill | — | $483k | 1 |
| CAMP RISE ABOVE INC | Charleston | N20 Recreation & Sports | $482k | 1 |
| SOUTH CAROLINA FIRST STEPS TO | Greenwood | B012 Education | $482k | 0 |
| SOUTH CAROLINA FIRST STEPS TO | Greenwood | B012 Education | $482k | 1 |
| South Carolina State Univ National Alumni Associat | Orangeburg | B84 Education | $481k | 0 |
| THE COHEN FAMILY FOUNDATION | Mount Pleasant | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $481k | 1 |
| 3GEN MINISTRIES | Greer | X20 Religion-Related | $480k | 3 |
| IN HIS NAME - COLLETON | Walterboro | P20 Human Services | $480k | 1 |
| FOUNDATION FOR THE CHILD VICTIMS OF THE FAMILY COURT LLC | Greenville | O50 Youth Development | $480k | 1 |
| LAVIE PREGNANCY CARE CENTER | Lexington | E40 Health Care | $479k | 0 |
| ROAD RUNNERS CLUB OF AMERICA | Greenville | — | $479k | 0 |
| LAKE WYLIE ATHLETIC ASSOCIATION INC | Clover | N99 Recreation & Sports | $478k | 0 |
| LIMITLESS COMMUNITY DEVELOPMENT | Columbia | S20 Community Improvement & Capacity Building | $477k | 1 |
| PICKENS COUNTY ADVOCACY CENTER INC | Easley | F42Z Mental Health & Crisis Intervention | $477k | 1 |
| WANDO HIGH SCHOOL BAND BOOSTER | Mt Pleasant | B99Z Education | $476k | 0 |
| PIEDMONT INTERSTATE FAIR | Spartanburg | N520 Recreation & Sports | $476k | 1 |
