| Rotary International District 7750 | Anderson | — | $300k | 0 |
| FYREBIRD RECOVERY | Myrtle Beach | P20 Human Services | $300k | 0 |
| COMMUNITY WELLNESS OUTREACH | Columbia | F20 Mental Health & Crisis Intervention | $300k | 0 |
| Swamp Fox Trails | Florence | P20 Human Services | $300k | 0 |
| PALMETTO PREPARATORY ACADEMY INC | Columbia | — | $300k | 0 |
| I AM VOICES INC | Summerville | P20 Human Services | $300k | 1 |
| LOWCOUNTRY MARITIME SCHOOL | Mount Pleasant | B99 Education | $299k | 1 |
| SIXTY-TWO PLAZA CENTRAL INC | Easley | — | $299k | 0 |
| LOUIS D SIMMONS AMERICAN LEGION POST 215 | Columbia | — | $299k | 0 |
| THE JOANNA FOUNDATION | Sullivans Island | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $299k | 1 |
| Central Midlands Justice Ministry | Columbia | S99 Community Improvement & Capacity Building | $299k | 1 |
| LOUVENIA D BARKSDALE SICKLE CELL ANEMIA FOUNDATIO | Spartanburg | G22Z Diseases, Disorders & Medical Disciplines | $299k | 5 |
| Domestic Abuse Center | Columbia | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $299k | 2 |
| Center for Global Strategies LTD | Greenville | Q30 International, Foreign Affairs & National Security | $298k | 1 |
| Christian Families Against Destructive Decisions | Spartanburg | L990 Housing & Shelter | $298k | 0 |
| JOHN DE LA HOWE SCHOOL FOUNDATION | McCormick | B11 Education | $298k | 1 |
| CHARLESTON COMMUNITY SAILING INC | Charleston | N67 Recreation & Sports | $298k | 0 |
| HOPE MISSIONS OF THE UPSTATE | Anderson | X20 Religion-Related | $298k | 1 |
| COOLEY SPRINGS FINGERVILLE FIRE INC | Chesnee | — | $297k | 0 |
| Piedmont Regional Association of Realtors Inc | Rock Hill | — | $297k | 0 |
| Dream Preparatory Academy Inc | Greenville | B90 Education | $297k | 0 |
| All Things Possible Medical Fundraising | Fort Mill | P50 Human Services | $297k | 1 |
| MT PLEASANT CHAMBER OF COMMERCE | Mt Pleasant | — | $297k | 0 |
| AMERICAN FEDERATION OF GOVERNMENT EMPLOYEES | Anderson | — | $297k | 4 |
| CBL STATE SAVINGS BANK FOUNDATION | Greer | T21 Philanthropy, Voluntarism & Grantmaking Foundations | $296k | 0 |
| PALMETTO STATE ARTS EDUCATION | Rock Hill | — | $296k | 1 |
| CITIZENS FOR NUCLEAR TECHNOLOGY AWARENESS | Aiken | C99 Environment | $296k | 1 |
| PRESERVING OUR SOUTHERN APPALACHIAN MUSIC INC | Easley | A68 Arts, Culture & Humanities | $296k | 0 |
| Still Worthy Inc | Johns Island | F20 Mental Health & Crisis Intervention | $296k | 1 |
| BALLET OF YORK COUNTY | Rock Hill | A20 Arts, Culture & Humanities | $295k | 1 |
| COLUMBUS HOPE FOUNDATION INC | Pawleys Island | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $295k | 0 |
| NATIONAL RETIRED MILITARY GOLF CLASSIC INC | Columbia | N6A Recreation & Sports | $295k | 0 |
| May River High School Booster Club | Bluffton | T50 Philanthropy, Voluntarism & Grantmaking Foundations | $295k | 0 |
| PRESTWOOD COUNTRY CLUB | Hartsville | N51Z Recreation & Sports | $295k | 0 |
| J M SMITH FOUNDATION | Spartanburg | T21Z Philanthropy, Voluntarism & Grantmaking Foundations | $295k | 0 |
| THE GRANT FAMILY FOUNDATION | Greenville | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $295k | 0 |
| New Way Global | Greenville | P20 Human Services | $294k | 1 |
| CREEKSIDE HOUSING CORPORATION | Greenville | P70 Human Services | $294k | 0 |
| THE MUSEUM - GREENWOOD SOUTH CAROLINA | Greenwood | A540 Arts, Culture & Humanities | $294k | 1 |
| LIFE OVER COFFEE | Greer | F60 Mental Health & Crisis Intervention | $293k | 2 |
| MAGNOLIA MEMORY CARE INC | Fort Mill | — | $293k | 1 |
| SENIOR MENS GOLF ASSOCIATION OF HILTON HEAD ISLAND INCORPORATED | Hilton Head Island | — | $293k | 7 |
| ANGEL'S CHARGE MINISTRY | Spartanburg | I31 Crime & Legal-Related | $293k | 1 |
| CONWAY SOLID GOLD INC | Conway | N11 Recreation & Sports | $293k | 0 |
| JC CARES | Easley | X20 Religion-Related | $293k | 0 |
| CATAWBA RIDGE HIGH SCHOOL ATHLETIC BOOSTER CLUB | Fort Mill | N99 Recreation & Sports | $293k | 0 |
| CALHOUN COUNTY FIRST STEPS TO SCHOOL READINESS PARTNERSHIP | Greenwood | B012 Education | $292k | 1 |
| MOUNTAIN VIEW PREPARATORY | Elgin | B29 Education | $292k | 0 |
| SC-QRF | Greenville | W30 Public & Societal Benefit | $292k | 0 |
| SC PROGRESSIVE NETWORK EDUCATION FUND | Columbia | B90 Education | $292k | 2 |
