| HEALTH CARE CENTERS IN SCHOOLS | Baton Rouge | E30 Health Care | $5.8M | 5 |
| NORTH FRANKLIN WATER WORKS INC | Crowville | — | $5.8M | 0 |
| LOUISIANA ATTORNEY DISCIPLINARY BOARD | Metairie | I03 Crime & Legal-Related | $5.7M | 2 |
| CAPITAL AREA UNITED WAY | Baton Rouge | T700 Philanthropy, Voluntarism & Grantmaking Foundations | $5.7M | 1 |
| GREATER NEW ORLEANS EDUCATIONAL | New Orleans | A320 Arts, Culture & Humanities | $5.7M | 3 |
| TEAM GLEASON FOUNDATION | New Orleans | P20 Human Services | $5.6M | 2 |
| Louisiana Leadership Institute | Baton Rouge | B12 Education | $5.6M | 0 |
| GOODWORKS INC | New Orleans | P82 Human Services | $5.6M | 7 |
| The Joe W and Dorothy D Brown | Metairie | B12 Education | $5.6M | 4 |
| LOUISIANA ASSOCIATION OF UNITED WAYS INC | Baton Rouge | T70 Philanthropy, Voluntarism & Grantmaking Foundations | $5.6M | 1 |
| VILLA ST FRANCIS | Baton Rouge | — | $5.6M | 5 |
| ST NICHOLAS CENTER FOR CHILDREN | Lake Charles | P82 Human Services | $5.5M | 1 |
| THE ORCHARD FOUNDATION | Alexandria | B022 Education | $5.5M | 6 |
| Southwest Louisiana Independence Center Inc | Lake Charles | P80Z Human Services | $5.5M | 1 |
| ROSAMARY FOUNDATION | New Orleans | — | $5.5M | 0 |
| PRESBYTERIAN VILLAGE OF HOMER | Homer | E91Z Health Care | $5.5M | 0 |
| GREATER NEW ORLEANS DEVELOPMENT | New Orleans | S300 Community Improvement & Capacity Building | $5.5M | 5 |
| COUNCIL ON ALCOHOLISM & DRUG ABUSE OF NORTHWEST LOUISIANA | Shreveport | F22Z Mental Health & Crisis Intervention | $5.4M | 0 |
| VOLUNTEERS FOR YOUTH JUSTICE | Shreveport | — | $5.4M | 0 |
| GRAMBLING UNIVERSITY FOUNDATION INC | Grambling | B19 Education | $5.4M | 0 |
| DOMINO SUGAR CORPORATION AND LOCAL 1101 | Arabi | — | $5.4M | 0 |
| COMMUNITY FOUNDATION OF SOUTHWEST | Lake Charles | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $5.3M | 1 |
| CHRISTIAN OUTREACH CENTER | Baton Rouge | F20 Mental Health & Crisis Intervention | $5.3M | 1 |
| BRCC FACILITIES CORPORATION | Baton Rouge | B82 Education | $5.3M | 0 |
| SOUTH LOUISIANA ELECTRIC | Houma | — | $5.3M | 11 |
| Adrienne Helis Malvin Medical | New Orleans | G05 Diseases, Disorders & Medical Disciplines | $5.3M | 0 |
| JCFA | Harvey | B29 Education | $5.3M | 2 |
| LOUISIANA HEALTH CARE QUALITY FORUM | Baton Rouge | E05 Health Care | $5.3M | 5 |
| THE ARC OF SABINE INC | Many | — | $5.3M | 1 |
| L S U PROPERTY FOUNDATION | Baton Rouge | T50 Philanthropy, Voluntarism & Grantmaking Foundations | $5.2M | 3 |
| THE EDWARD L RISPONE FAMILY FOUNDATION | Baton Rouge | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $5.2M | 0 |
| Catalyst Education Inc | New Orleans | B02 Education | $5.2M | 7 |
| ALEXANDRIA COUNTRY DAY SCHOOL | Alexandria | B240 Education | $5.2M | 0 |
| ADVOCATES FOR INNOVATIVE SCHOOLSINC | New Orleans | B24 Education | $5.1M | 3 |
| THE HONOR SOCIETY OF PHI KAPPA PHI | Baton Rouge | B830 Education | $5.1M | 4 |
| CAJUN AREA AGENCY ON AGING | Lafayette | P81Z Human Services | $5.1M | 0 |
| THE PHILADELPHIA CENTER | Shreveport | — | $5.1M | 0 |
| AMERICA NEXT | Baton Rouge | E99 Health Care | $5.1M | 1 |
| United Way of Southwest Louisiana Inc | Lake Charles | — | $5.1M | 2 |
| CATHOLIC FOUNDATION OF SOUTH LOUISIANA | Schriever | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $5M | 1 |
| SILLIMAN INSTITUTE INC | Clinton | B20 Education | $5M | 0 |
| HORSEMEN'S WORKERS' COMPENSATION | New Orleans | Y25 Mutual & Membership Benefit | $5M | 1 |
| MER ROUGE COMMUNITY SERVICES INC | Mer Rouge | — | $5M | 0 |
| GOOD SHEPHERD NATIVITY MISSION SCHOOL | New Orleans | B24 Education | $5M | 1 |
| Slaughter Community Charter School | Slaughter | B29 Education | $5M | 1 |
| The ARC of St Charles Inc | Boutte | — | $4.9M | 1 |
| AMITE INDEPENDENT SCHOOL INC | Amite | B24Z Education | $4.9M | 0 |
| BATON ROUGE AREA CHAMBER | Baton Rouge | — | $4.9M | 9 |
| GENERAL HEALTH SYSTEM FOUNDATION | Baton Rouge | — | $4.9M | 3 |
| Provident Group HSC Properties Inc | Baton Rouge | B11 Education | $4.9M | 4 |
