| OCHSNER CLINIC FOUNDATION | New Orleans | E220 Health Care | $6B | 46 |
| OUR LADY OF THE LAKE HOSPITAL INC | Baton Rouge | E220 Health Care | $1.9B | 17 |
| THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND | New Orleans | B430 Education | $1.8B | 19 |
| LOUISIANA CHILDREN'S MEDICAL CENTER | New Orleans | E20 Health Care | $1.6B | 16 |
| WILLIS-KNIGHTON MEDICAL CENTER | Shreveport | E220 Health Care | $1.5B | 14 |
| OCHSNER LSU HEALTH SYSTEM OF NORTH LOUISIANA | Shreveport | E22 Health Care | $1B | 5 |
| WOMAN'S HOSPITAL FOUNDATION D/B/A WOMAN'S HOSPITAL | Baton Rouge | E240 Health Care | $897.5M | 18 |
| UNIVERSITY MEDICAL CENTER MANAGEMENT CORPORATION | New Orleans | G12 Diseases, Disorders & Medical Disciplines | $760M | 18 |
| CHILDREN'S HOSPITAL INC | New Orleans | E240 Health Care | $737.3M | 11 |
| LAFAYETTE GENERAL MEDICAL CENTER INC | Lafayette | E220 Health Care | $734.9M | 22 |
| BATON ROUGE GENERAL MEDICAL CENTER | Baton Rouge | E220 Health Care | $688.7M | 20 |
| OUR LADY OF LOURDES REGIONAL MEDICAL CENTER INC | Baton Rouge | E220 Health Care | $628.4M | 18 |
| SOUTHWEST LOUISIANA HOSPITAL ASSOCIATION D/B/A LAKE CHARLES MEMORIAL HOSPITAL | Lake Charles | E220 Health Care | $502.3M | 21 |
| ST FRANCIS MEDICAL CENTER | Baton Rouge | E220 Health Care | $433.2M | 15 |
| Christus Health Central Louisiana | Alexandria | E220 Health Care | $426.7M | 24 |
| FRANCISCAN MISSIONARIES OF OUR LADY HEALTH SYSTEM INC | Baton Rouge | E21Z Health Care | $369M | 19 |
| TOURO INFIRMARY | New Orleans | E220 Health Care | $367.3M | 22 |
| LCMC HEALTH HOLDINGS INC | Metairie | — | $353.3M | 15 |
| THIBODAUX REGIONAL HEALTH SYSTEM INC | Thibodaux | E20 Health Care | $348.2M | 9 |
| Christus Health Northern Louisiana | Shreveport | E200 Health Care | $333.6M | 14 |
| Provident Resources Group Inc | Baton Rouge | E91 Health Care | $321.6M | 15 |
| Christus Health Southwestern Louisiana | Lake Charles | E220 Health Care | $306.2M | 17 |
| SOUTHWEST LOUISIANA ELECTRIC MEMBERSHIP CORPORATION | Lafayette | — | $303.8M | 19 |
| DIXIE ELECTRIC MEMBERSHIP CORPORATION | Baton Rouge | — | $274.5M | 24 |
| LAFAYETTE GENERAL HEALTH SYSTEM INC | Lafayette | E21 Health Care | $258.3M | 17 |
| MARY BIRD PERKINS CANCER CENTER | Baton Rouge | G30Z Diseases, Disorders & Medical Disciplines | $229.6M | 8 |
| UNIVERSITY HOSPITAL & CLINICS INC | Lafayette | E20 Health Care | $222.7M | 8 |
| COMMCARE CORPORATION | Mandeville | E910 Health Care | $220.3M | 11 |
| LOYOLA UNIVERSITY | New Orleans | B430 Education | $216.8M | 16 |
| LOUISIANA INSURANCE GUARANTY ASSOCIATION | Baton Rouge | — | $213.4M | 5 |
| LSU HEALTH SCIENCES CENTER - SHREVEPORT FACULTY GROUP PRACTICE | Shreveport | F30 Mental Health & Crisis Intervention | $204.8M | 3 |
| Beauregard Electric Cooperative | DeRidder | — | $163M | 23 |
| LOUISIANA STATE UNIVERSITY SCHOOL OF MED IN NEW ORLEANS FACULTY GROUP PRACTICE | New Orleans | E31Z Health Care | $161.3M | 13 |
| XAVIER UNIVERSITY OF LOUISIANA | New Orleans | B430 Education | $158.7M | 15 |
| THE ALTA AND JOHN FRANKS FOUNDATION | Shreveport | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $150.1M | 3 |
| GENERAL HEALTH SYSTEM | Baton Rouge | E210 Health Care | $138.2M | 21 |
| WASHINGTON-ST TAMMANY ELECTRIC COOPERATIVE INC 1570 | Franklinton | — | $124.8M | 16 |
| KIPP OF NEW ORLEANS INC | New Orleans | B29 Education | $117.9M | 8 |
| SECOND HARVEST FOOD BANK GREATER NEW ORLEANS AND ACADIANA | New Orleans | K190 Food, Agriculture & Nutrition | $101M | 10 |
| LOUISIANA SHERIFFS ASSOCIATION GROUP BENEFITS TRUST | Baton Rouge | Y43 Mutual & Membership Benefit | $100.3M | 0 |
| THE NATIONAL WORLD WAR II MUSEUM INC | New Orleans | A540 Arts, Culture & Humanities | $100.2M | 18 |
| INSPIRENOLA CHARTER SCHOOLS | New Orleans | B20 Education | $93.9M | 10 |
| PELICAN STATE CREDIT UNION | Baton Rouge | — | $88.5M | 20 |
| TIGER ATHLETIC FOUNDATION | Baton Rouge | B110 Education | $86.8M | 11 |
| LSU FOUNDATION | Baton Rouge | B110 Education | $81.9M | 10 |
| NEW ORLEANS JAZZ & HERITAGE FESTIVAL AND FOUNDATION INC | New Orleans | A6C0 Arts, Culture & Humanities | $73.7M | 32 |
| NOAIDS TASK FORCE | New Orleans | — | $73.5M | 8 |
| Claiborne Electric Cooperative Inc | Homer | — | $73.5M | 16 |
| GOLDRING FAMILY FOUNDATION | Metairie | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $73.5M | 0 |
| CHILDRENS HOSPITAL ANESTHESIA CORPORATION | New Orleans | E60 Health Care | $73.4M | 8 |
