| COMITE DESARROLLO SOCIAL Y CULTURAL DAGUAO INC | Naguabo | S20 Community Improvement & Capacity Building | $81k | 0 |
| CASA TALLABOENA DE FORMACION COMUNITARIA Y RESILIENCIA INC | Penuelas | S20 Community Improvement & Capacity Building | $79k | 0 |
| FEDERACION PROTECTORA DE ANIMALES DE PR INC | Guaynabo | D20 Animal-Related | $78k | 0 |
| CASA DE TRANSFORMACION Y RESTAURACION FAMILIAR INC | Dorado | F32 Mental Health & Crisis Intervention | $78k | 0 |
| ACADEMIA DE PATOLOGIA Y MEDICINA DE LABORATORIO | San Juan | B03 Education | $77k | 0 |
| FUNDACION EDUCAMOS CON AMOR INC | Corozal | P20 Human Services | $77k | 1 |
| La Casa de la Plena Tito Matos Inc | San Juan | A20 Arts, Culture & Humanities | $77k | 0 |
| THE POLARIS ART FOUNDATION | San Juan | A80 Arts, Culture & Humanities | $76k | 0 |
| DANZACTIVA INC | San Juan | A62 Arts, Culture & Humanities | $76k | 1 |
| FUNDACION ASISTENCIA CENTRO DE TRAUMA INC | San Juan | E32 Health Care | $75k | 0 |
| FUNDACION PUERTORRIQUENA DE | San Juan | E70 Health Care | $75k | 1 |
| COALICION DE CANCER COLORRECTAL DE PUERTO RICO INC | San Juan | G30 Diseases, Disorders & Medical Disciplines | $73k | 0 |
| MOCHILEANDO 100X35 | San Juan | M20 Public Safety, Disaster Preparedness & Relief | $73k | 0 |
| UNITED STEEL WORKERS LOCAL 04-6135 | Bayamon | — | $73k | 6 |
| ROME FESTIVAL ORCHESTRA LTD | Luquillo | A68Z Arts, Culture & Humanities | $73k | 0 |
| ASOCIACION DE ALZHEIMER Y DESORDENES RELACIONADOS DE PR | San Juan | G83 Diseases, Disorders & Medical Disciplines | $71k | 0 |
| ECOS DE VIDA | Guaynabo | B90 Education | $70k | 0 |
| CENTRO DE INVESTIGACIONES FOLKLORICAS DE PUERTO RICO INC | Ponce | — | $70k | 0 |
| FUNDACION EDUCATIVA ASORE INC | Guaynabo | K12 Food, Agriculture & Nutrition | $70k | 1 |
| SERVICIOS EDUCATIVOS EBENEZER INC | Toa Alta | B90 Education | $68k | 1 |
| COMUNIDAD LASC CRUCES INC | Naranjito | W80 Public & Societal Benefit | $68k | 0 |
| A NEW LIFE MENS CENTER INC | Coamo | F20 Mental Health & Crisis Intervention | $68k | 0 |
| SOCIEDAD DE MEDICINA NUCLEAR E | San Juan | S41 Community Improvement & Capacity Building | $68k | 0 |
| FUNDACION SANTOS YAEL ALONSO INC | Anasco | N6A Recreation & Sports | $67k | 0 |
| Kids 4 Green Culebra Inc | Culebra | P20 Human Services | $67k | 0 |
| CONNECTING PATHS PR INC | San Juan | P20 Human Services | $67k | 1 |
| PUERTO RICO ORGANIZACIONES VOLUNTARIAS ACTIVAS EN DESASTRES | San Juan | M11 Public Safety, Disaster Preparedness & Relief | $65k | 0 |
| VIEQUES ROTARY CLUB INC | Vieques | S80 Community Improvement & Capacity Building | $64k | 0 |
| K & Z Servicios De Consejeria Multiple | Luquillo Co | P20 Human Services | $64k | 13 |
| INTERNATIONAL UNION UNITED AUTO AEROSPACE & AGRICULTURAL WORKERS | Carolina | — | $62k | 1 |
| FUNDACION COAMENOS POR LA NINEZ INC | Coamo | P30 Human Services | $61k | 0 |
| MUSEO DE LA HISTORIA DE SAN GERMAN | San German | A54 Arts, Culture & Humanities | $61k | 0 |
| FRIENDS OF CULEBRA ANIMALS INC | Culebra | D20 Animal-Related | $61k | 0 |
| LICEO DE ARTE DEL SUR INC | Ponce | A25 Arts, Culture & Humanities | $60k | 0 |
| RICO INC | San Juan | K99 Food, Agriculture & Nutrition | $58k | 1 |
| INTERNATIONAL UNION UNITED AUTO AEROSPACE & AGRICULTURAL WORKERS | Carolina | — | $57k | 0 |
| ACUEDUCTO RURAL PALMARITO CINTRON INC | Corozal | W80 Public & Societal Benefit | $56k | 0 |
| CHRISTIAN SCHOOL AND CHAPEL FOR THE DEAF | Luquillo | B28 Education | $56k | 0 |
| SANTUARIO DE ANIMALES DE BARRANQUITAS INC | Barranquitas | D20 Animal-Related | $56k | 0 |
| SCARAMELLA FAITH FOUNDATION INC | Rio Grande | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $56k | 0 |
| INTERNATIONAL UNION UNITED AUTO AEROSPACE & AGRICULTURAL WORKERS | Carolina | — | $55k | 2 |
| COOPERATIVA DE ENERGIA LA MARGARITA - ABEYNO COOP | Salinas | C35 Environment | $54k | 0 |
| FUNDACION ONCOLOGICA HIMA-SAN PABLO INC | Caguas | — | $54k | 0 |
| OYE Corporation | San Juan | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $53k | 0 |
| CONCERNED RESIDENTS FOR IMPROVEMENT | Vieques | B90 Education | $53k | 0 |
| EDUCATIONAL CENTER FOR THE BLIND AND THE HANDICAPPED OF PUERTO RICO | San Juan | A33Z Arts, Culture & Humanities | $53k | 1 |
| ASOCIACION DE RESIDENTES CAMIN | Adjuntas | S20 Community Improvement & Capacity Building | $52k | 0 |
| HOOVES ON THE GROUND INC | Vieques | D20 Animal-Related | $50k | 0 |
| CANTUTA MONTESSORI CORP | Ponce | B28 Education | $50k | 0 |
| Acueducto Rural El Manantial | Caguas | W80 Public & Societal Benefit | $50k | 0 |
