| DISCOVERY SCHOOL OF LANCASTER | Lancaster | B29 Education | $2.1M | 1 |
| A Father's Place | Conway | B99 Education | $2.1M | 1 |
| MASC GROUP INS TR | North Charleston | — | $2.1M | 0 |
| GREENWOOD GENETIC CENTER FOUNDATION | Greenwood | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $2.1M | 4 |
| STEVEN M AND JOYCE E TADLER | Kiawah Island | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $2.1M | 0 |
| FIVE POINTS ASSOCIATION INC | Columbia | E50 Health Care | $2.1M | 1 |
| SOUTH CAROLINA ASSOCIATION FOR JUSTICE | Columbia | — | $2.1M | 2 |
| GREENVILLE CHAMBER FOUNDATION INC | Greenville | — | $2.1M | 0 |
| SMITH MEDICAL CLINIC INC | Pawleys Island | — | $2.1M | 1 |
| MCCORMICK ARTS COUNCIL AT THE KETURAH INC | Mc Cormick | — | $2.1M | 0 |
| UNITED WAY OF AIKEN COUNTY INC | Aiken | — | $2.1M | 1 |
| THE CAROLINA ACADEMY | Lake City | B24Z Education | $2.1M | 0 |
| CENTRAL CAROLINA ECONOMIC DEVELOPMENT | Columbia | S30Z Community Improvement & Capacity Building | $2.1M | 2 |
| SENECA IMPROVEMENTS CORPORATION | Seneca | S30 Community Improvement & Capacity Building | $2.1M | 0 |
| SOUTHEASTERN ASSOC OF FISH AND WILDLIFE | Aiken | — | $2.1M | 2 |
| LOW COUNTRY EDUCATION CONSORTIUM | Aynor | B90 Education | $2.1M | 1 |
| MEANSVILLE-RILEY ROAD WATER COMPANY | Union | Y22 Mutual & Membership Benefit | $2.1M | 10 |
| FRAZZA FAMILY FOUNDATION INC | Fort Mill | — | $2.1M | 0 |
| South Carolina Universities Research & | Aiken | — | $2.1M | 1 |
| UPSTATE FAMILY RESOURCE CENTER | Boiling Springs | P40 Human Services | $2.1M | 1 |
| HOWARD B SHERMAN FOUNDATION TRUST | Charleston | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $2.1M | 0 |
| SOUTH CAROLINA VICTIM ASSISTANCE | Columbia | — | $2.1M | 1 |
| THOMAS HEYWARD ACADEMY INC | Ridgeland | B24Z Education | $2.1M | 1 |
| BIG RED BARN RETREAT | Blythewood | P80 Human Services | $2.1M | 0 |
| Tender Hearts Girls Home Inc | York | P73 Human Services | $2.1M | 1 |
| DANIEL ISLAND COMMUNITY FUND INC | Charleston | S20 Community Improvement & Capacity Building | $2.1M | 0 |
| SOUTH CAROLINA UNITED METHODIST | Columbia | — | $2.1M | 1 |
| HOBCAW YACHT CLUB | Mt Pleasant | — | $2.1M | 0 |
| LAMB INSTITUTE | Mount Pleasant | X20 Religion-Related | $2.1M | 1 |
| ASIA WILD | Charleston | D30 Animal-Related | $2.1M | 2 |
| JOHN CALVIN BIBLE FOUNDATION INC | Lancaster | T90 Philanthropy, Voluntarism & Grantmaking Foundations | $2.1M | 0 |
| RICHARD WINN ACADEMY | Winnsboro | — | $2.1M | 1 |
| THE BIRK FAMILY FOUNDATION INC | Mt Pleasant | T20J Philanthropy, Voluntarism & Grantmaking Foundations | $2M | 0 |
| BARNWELL COUNTY COMMISSION ON ALCOHOL | Barnwell | F20 Mental Health & Crisis Intervention | $2M | 1 |
| SOUTH CAROLINA FIRST STEPS TO | Greenwood | B012 Education | $2M | 0 |
| SEA HAVEN INC | North Myrtle Beach | I440 Crime & Legal-Related | $2M | 1 |
| JAMAICA RELIEF MINISTRIES INC | Fair Play | P60 Human Services | $2M | 2 |
| PALMETTOPRIDE THE GOVERNOR'S | Columbia | C015 Environment | $2M | 1 |
| GRAND STRAND HUMANE SOCIETY INC | Myrtle Beach | D200 Animal-Related | $2M | 1 |
| YORK TECHNICAL COLLEGE | Rock Hill | B42I Education | $2M | 2 |
| MAINSAIL HEALTH PARTNERS | Charleston | E11 Health Care | $2M | 1 |
| HOLLY HILL ACADEMY INC | Holly Hill | B20 Education | $2M | 1 |
| CLEMSON UNIVERSITY RESEARCH FOUNDATION | Clemson | B110 Education | $2M | 7 |
| South Carolina United Methodist | Greenville | — | $2M | 1 |
| GREATER COLUMBIA CHAMBER OF COMMERCE | Columbia | — | $2M | 1 |
| GOUCHER CHARTER SCHOOL | Gaffney | B29 Education | $2M | 1 |
| SEED PLANTERS FOUNDATION INC | Awendaw | T99 Philanthropy, Voluntarism & Grantmaking Foundations | $2M | 0 |
| CHARLESTON JEWISH FEDERATION INC | Charleston | T70Z Philanthropy, Voluntarism & Grantmaking Foundations | $2M | 1 |
| CHARLESTON AREA SENIOR CITIZENS INC | Charleston | — | $2M | 0 |
| FIRST PRESBYTERIAN CHURCH | Columbia | F60 Mental Health & Crisis Intervention | $2M | 2 |
