| UNCOMMON CHARITABLE IMPACT INC | Charleston | T99 Philanthropy, Voluntarism & Grantmaking Foundations | $2.2M | 1 |
| MIDLAND VALLEY CHRISTIAN ACADEMY | Clearwater | B20 Education | $2.2M | 0 |
| DOWNTOWN PARTNERSHIP COMMITTEE NONPROFIT CORPORATION | Spartanburg | W20 Public & Societal Benefit | $2.2M | 6 |
| GREENVILLE COUNTY FIRST STEPS TO SCHOOL READINESS PARTNERSHIP | Greenwood | B012 Education | $2.2M | 1 |
| OPERATION PATRIOTS FOB INC | Okatie | T11 Philanthropy, Voluntarism & Grantmaking Foundations | $2.2M | 2 |
| PIEDMONT AGENCY ON AGING INC | Greenwood | P81Z Human Services | $2.2M | 1 |
| THE MONTESSORI SCHOOL OF CAMDEN | Camden | B29 Education | $2.1M | 1 |
| EDUCATIONAL FACILITIES CORPORATION FOR LEXINGTON SCHOOL DISTRICT NO 2 | West Columbia | T990 Philanthropy, Voluntarism & Grantmaking Foundations | $2.1M | 2 |
| ARRHYTHMIA TECHNOLOGIES INSTITUTE INC | Greenville | — | $2.1M | 2 |
| NORTHSIDE DEVELOPMENT CORPORATION | Spartanburg | S30 Community Improvement & Capacity Building | $2.1M | 1 |
| MEALS ON WHEELS INC | Anderson | — | $2.1M | 1 |
| FAIR PLAY CAMP SCHOOL INC | Westminster | F33Z Mental Health & Crisis Intervention | $2.1M | 1 |
| HABITAT FOR HUMANITY OF ANDERSON INC | Anderson | — | $2.1M | 1 |
| SOUTH CAROLINA HEALTH CARE ASSOCIATION | Columbia | — | $2.1M | 1 |
| A Father's Place | Conway | B99 Education | $2.1M | 1 |
| MASC GROUP INS TR | North Charleston | — | $2.1M | 0 |
| GREENWOOD GENETIC CENTER FOUNDATION | Greenwood | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $2.1M | 4 |
| SOUTH CAROLINA ASSOCIATION FOR JUSTICE | Columbia | — | $2.1M | 2 |
| SERVE AND CONNECT | Columbia | P20 Human Services | $2.1M | 1 |
| CAROLINA SCHOOL FOR INQUIRY | Columbia | B29 Education | $2.1M | 1 |
| UNIVERSITY OF SOUTH CAROLINA UPSTATE FOUNDATION | Spartanburg | — | $2.1M | 1 |
| SMITH MEDICAL CLINIC INC | Pawleys Island | — | $2.1M | 1 |
| MCCORMICK ARTS COUNCIL AT THE KETURAH INC | Mc Cormick | — | $2.1M | 0 |
| FRANCES P BUNNELLE FOUNDATION COASTAL COMMUNITY FOUNDATION OF SC | Pawleys Island | T12 Philanthropy, Voluntarism & Grantmaking Foundations | $2.1M | 2 |
| THE CAROLINA ACADEMY | Lake City | B24Z Education | $2.1M | 0 |
| CENTRAL CAROLINA ECONOMIC DEVELOPMENT ALLIANCE | Columbia | S30Z Community Improvement & Capacity Building | $2.1M | 2 |
| SENECA IMPROVEMENTS CORPORATION | Seneca | S30 Community Improvement & Capacity Building | $2.1M | 0 |
| SOUTHEASTERN ASSOC OF FISH AND WILDLIFE AGENCIES INC | Aiken | — | $2.1M | 2 |
| MEANSVILLE-RILEY ROAD WATER COMPANY INC | Union | Y22 Mutual & Membership Benefit | $2.1M | 10 |
| HOWARD B SHERMAN FOUNDATION TRUST UTA DATED 04102024 | Charleston | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $2.1M | 0 |
| THOMAS HEYWARD ACADEMY INC | Ridgeland | B24Z Education | $2.1M | 1 |
| DANIEL ISLAND COMMUNITY FUND INC | Charleston | S20 Community Improvement & Capacity Building | $2.1M | 0 |
| EPISCOPAL DIOCESAN HOUSING INC | Charleston | L20Z Housing & Shelter | $2.1M | 0 |
| SOUTH CAROLINA UNITED METHODIST FOUNDATION INC | Columbia | — | $2.1M | 1 |
| SOUTH CAROLINA GOVERNOR'S SCHOOL FOR THE ARTS AND HUMANITIES FDTN | Greenville | — | $2.1M | 1 |
| HOBCAW YACHT CLUB | Mt Pleasant | — | $2.1M | 0 |
| PROVIDENCE CLASSICAL SCHOOL | Rock Hill | B24 Education | $2.1M | 0 |
| SOUTHERN EVANGELICAL SEMINARY | Rock Hill | — | $2.1M | 1 |
| LAMB INSTITUTE | Mount Pleasant | X20 Religion-Related | $2.1M | 1 |
| JOHN CALVIN BIBLE FOUNDATION INC | Lancaster | T90 Philanthropy, Voluntarism & Grantmaking Foundations | $2.1M | 0 |
| SCBIO | Greenville | — | $2.1M | 2 |
| RICHARD WINN ACADEMY | Winnsboro | — | $2.1M | 1 |
| Educational Foundation of USCL Inc | Lancaster | B82Z Education | $2.1M | 0 |
| BARNWELL COUNTY COMMISSION ON ALCOHOL AND DRUG ABUSE | Barnwell | F20 Mental Health & Crisis Intervention | $2M | 1 |
| THE TOBY CASSELS FOUNDATION | Lexington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $2M | 0 |
| JAMAICA RELIEF MINISTRIES INC | Fair Play | P60 Human Services | $2M | 2 |
| YORK TECHNICAL COLLEGE FOUNDATION INC | Rock Hill | B42I Education | $2M | 2 |
| HOLLY HILL ACADEMY INC | Holly Hill | B20 Education | $2M | 1 |
| SOUTH CAROLINA VICTIM ASSISTANCE NETWORK | Columbia | — | $2M | 1 |
| CLEMSON UNIVERSITY RESEARCH FOUNDATION | Clemson | B110 Education | $2M | 7 |
