| BEAUTIFUL GATE CENTER | North Charleston | G84 Diseases, Disorders & Medical Disciplines | $989k | 0 |
| YWCA OF GREATER CHARLESTON | Charleston | P27Z Human Services | $988k | 1 |
| LAMBDA THETA HOUSE CORPORATION OF | Columbia | S47 Community Improvement & Capacity Building | $987k | 0 |
| CREEKSIDE TENNIS AND SWIM CLUB | Mount Pleasant | — | $987k | 0 |
| ARTS CENTER OF KERSHAW COUNTY INC | Camden | A61Z Arts, Culture & Humanities | $986k | 1 |
| PROVIDENT BUSINESS FINANCIAL | West Columbia | S43 Community Improvement & Capacity Building | $984k | 3 |
| SOUTH CAROLINA FFA ASSOCIATION | Columbia | O52Z Youth Development | $983k | 1 |
| PERU MISSION USA INC | Greenville | B90 Education | $983k | 1 |
| SOUTH CAROLINA FIRST STEPS TO | Greenwood | B012 Education | $980k | 1 |
| Clemson Child Development Center | Clemson | — | $980k | 0 |
| GIVE HOPE INC | Fort Mill | T11 Philanthropy, Voluntarism & Grantmaking Foundations | $978k | 0 |
| SOUTH CAROLINA JUNIOR GOLF ASSOCIATION | Irmo | — | $977k | 1 |
| BERKELEY SENIORS INC | Moncks Corner | P81 Human Services | $977k | 0 |
| NEW ALPHA COMMUNITY DEVELOPMENT CORPORATION | Florence | S31 Community Improvement & Capacity Building | $977k | 0 |
| THE WAREHOUSE THEATRE | Greenville | A650 Arts, Culture & Humanities | $974k | 2 |
| LAST CHANCE ANIMAL RESCUE FUND INC | Carlisle | D20 Animal-Related | $973k | 2 |
| SPARTANBURG LITTLE THEATRE | Spartanburg | A650 Arts, Culture & Humanities | $972k | 1 |
| MH NEWTON FAMILY LIFE | Sumter | N31 Recreation & Sports | $972k | 0 |
| FRIENDS OF THE ANIMAL SHELTER INC | Aiken | D20 Animal-Related | $972k | 0 |
| ILA CLERKS AND CHECKERS LOCAL 1771 | Charleston | — | $972k | 6 |
| THE ORIGINAL SIX FOUNDATION | Columbia | S20 Community Improvement & Capacity Building | $971k | 2 |
| INTERNATIONAL BALLET | Greer | A63 Arts, Culture & Humanities | $971k | 0 |
| All About Change Inc | Greenville | P46 Human Services | $971k | 0 |
| DELANCEY STREET SOUTH CAROLINA | North Charleston | J30 Employment | $971k | 3 |
| WAKE UP CAROLINA | Mount Pleasant | F20 Mental Health & Crisis Intervention | $970k | 3 |
| Furman Youth Association Inc | Greenville | N630 Recreation & Sports | $969k | 1 |
| CAPITA SOCIAL INC | Greenville | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $969k | 1 |
| THE FIDUCIARY AND INVESTMENT RISK | Lancaster | S41 Community Improvement & Capacity Building | $969k | 1 |
| THE BRIDGE CENTER RECOVERY | Anderson | P80 Human Services | $968k | 1 |
| SIGAL MUSIC MUSEUM | Greenville | A68 Arts, Culture & Humanities | $968k | 0 |
| GOUCHER WATER COMPANY INC | Pacolet | — | $966k | 0 |
| MID COUNTY WATER COMPANY INC | Winnsboro | — | $965k | 0 |
| STEEL DECK INSTITUTE | Florence | — | $964k | 1 |
| HIGHWAY EIGHTY-EIGHT WATER CO INC | Sandy Springs | W99 Public & Societal Benefit | $962k | 0 |
| Help Up Works Inc | Spartanburg | B99 Education | $961k | 0 |
| Carlos Dunlap Foundation Inc | Summerville | I21 Crime & Legal-Related | $961k | 0 |
| MISS SOUTH CAROLINA SCHOLARSHIP | Hartsville | B82 Education | $958k | 0 |
| FAIRFIELD COUNTY COUNCIL ON AGING | Winnsboro | P81 Human Services | $952k | 1 |
| THE COURAGE CENTER | Lexington | F20 Mental Health & Crisis Intervention | $951k | 2 |
| MONCKS CORNER RURAL FIRE DEPARTMENT | Moncks Corner | — | $950k | 3 |
| THE CHESTER FOUNDATION | Chester | — | $949k | 6 |
| ACCESSHEALTH HORRY INC | Conway | E80 Health Care | $949k | 0 |
| APRIL 30TH FOUNDATION | Hilton Head Island | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $949k | 0 |
| Auntie Karen Foundation | Columbia | O50 Youth Development | $948k | 1 |
| B T U REST HOME | Bennettsville | — | $945k | 1 |
| OPERATION GO INTERNATIONAL INC | Lexington | X21Z Religion-Related | $944k | 1 |
| CAROLINA ONE VOLLEYBALL | Simpsonville | N60 Recreation & Sports | $943k | 5 |
| PS I LOVE YOU MINISTRIES | Spartanburg | P30 Human Services | $940k | 1 |
| HELP 4 KIDS | Myrtle Beach | P20 Human Services | $938k | 0 |
| BROWN-LAWSON HOUSING DEVELOPMENT | Sumter | L21Z Housing & Shelter | $937k | 0 |
