| TECUMSEH AREA PARTNERSHIP INC | Lafayette | J200 Employment | $5.5M | 2 |
| GOODWILL LEADS INC | South Bend | B29 Education | $5.4M | 3 |
| CHILD ADVOCATES INC | Indianapolis | I82Z Crime & Legal-Related | $5.4M | 4 |
| NICHOLAS H NOYES JR MEMORIAL FOUNDATION | Carmel | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $5.4M | 2 |
| SHEET METAL WORKERS' LOCAL NO 20 APPRENTICESHIP AND TRAINING TRUST | Indianapolis | B30 Education | $5.4M | 3 |
| RICHMOND PROPERTY GROUP LTD | Indianapolis | — | $5.4M | 1 |
| SEVEN OAKS CLASSICAL SCHOOL INC | Ellettsville | B99 Education | $5.4M | 2 |
| COMMUNITY ACTION OF EAST CENTRAL INDIANA | Richmond | P20Z Human Services | $5.4M | 2 |
| SOUTH BEND HERITAGE FOUNDATION INC | South Bend | S200 Community Improvement & Capacity Building | $5.4M | 1 |
| HOOSIERS FOR GOOD INC | Bloomington | T99 Philanthropy, Voluntarism & Grantmaking Foundations | $5.4M | 0 |
| NOBLE COUNTY COMMUNITY FOUNDATION INC | Ligonier | T31Z Philanthropy, Voluntarism & Grantmaking Foundations | $5.4M | 1 |
| WESTFIELD YOUTH SOCCER ASSOCIATION | Westfield | N64Z Recreation & Sports | $5.3M | 4 |
| INDIANA CORN MARKETING COUNCIL | Indianapolis | K20 Food, Agriculture & Nutrition | $5.3M | 0 |
| INDIANAPOLIS URBAN LEAGUE INC | Indianapolis | P22Z Human Services | $5.3M | 1 |
| GATEWAY WOODS FAMILY SERVICES INC | Leo | O50 Youth Development | $5.3M | 1 |
| Humane Society for Hamilton County | Fishers | D200 Animal-Related | $5.3M | 1 |
| FOSTER SUCCESS | Indianapolis | P30 Human Services | $5.3M | 3 |
| Archdiocese of Indianapolis Cemeteries Inc | Indianapolis | X192 Religion-Related | $5.3M | 3 |
| GROW SOUTHWEST INDIANA WORKFORCE BOARD INC | Evansville | S30 Community Improvement & Capacity Building | $5.3M | 1 |
| JEAN AND BERNAS DOWNING CHARITABLE TRUST | Indianapolis | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $5.3M | 0 |
| BRICKLAYERS UNION LOCAL NO 6 OF INDIANA WELFARE FUND | Merrillville | — | $5.3M | 3 |
| THE HEALTH FOUNDATION OF GREATER INDIANAPOLIS INC | Indianapolis | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $5.2M | 1 |
| LOW COST SPAY-NEUTER CLINIC INC | Noblesville | D20 Animal-Related | $5.2M | 6 |
| GRACE SCHOOLS | Winona Lake | B58Z Education | $5.2M | 5 |
| NATIONAL POLICE ASSOCIATION INC | Indianapolis | B01 Education | $5.2M | 3 |
| St Margarets House | South Bend | N99 Recreation & Sports | $5.2M | 0 |
| INTERCHURCH FOOD PANTRY OF JOHNSON COUNTY | Whiteland | P20Z Human Services | $5.2M | 0 |
| ALPHA SIGMA PHI FRATERNITY INC | Carmel | — | $5.2M | 2 |
| LIBERTY GROVE SCHOOLS INC | Indianapolis | B20 Education | $5.2M | 2 |
| Lutheran Social Services Inc | Fort Wayne | P20Z Human Services | $5.2M | 2 |
| HYLES-ANDERSON COLLEGE INC | Crown Point | — | $5.2M | 0 |
| SOUTH CENTRAL LUTHERAN ASSOCIATION FOR SECONDARY EDUCATION INC | Seymour | B25 Education | $5.2M | 1 |
| WELBORN BAPTIST FOUNDATION INC | Evansville | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $5.2M | 1 |
| NATIONAL CONFERENCE OF INSURANCE GUARANTY FUNDS INC | Indianapolis | — | $5.2M | 5 |
| THE ARC OF INDIANA INC | Indianapolis | P82Z Human Services | $5.2M | 4 |
| SURACK FAMILY FOUNDATION INC | Fort Wayne | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $5.2M | 0 |
| YOUTH SERVICE BUREAU OF ST JOSEPH COUNTY INC | South Bend | P300 Human Services | $5.2M | 2 |
| OWEN COUNTY COMMUNITY FOUNDATION | Spencer | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $5.2M | 1 |
| DEACONESS VNA PLUS LLC | Evansville | E92 Health Care | $5.2M | 10 |
| MINNETRISTA CULTURAL FOUNDATIONINC | Muncie | — | $5.1M | 2 |
| M A ROONEY FOUNDATION INC | Indianapolis | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $5.1M | 3 |
| BOYS & GIRLS CLUBS OF NORTHEAST IND | Fort Wayne | O23Z Youth Development | $5.1M | 2 |
| NISOURCE NON-UNION LIFE & MEDICAL BENEFITS VEBA TRUST | Merrillville | Y43 Mutual & Membership Benefit | $5.1M | 0 |
| LAKE STATES DAIRY CENTER INC | Fair Oaks | A50 Arts, Culture & Humanities | $5.1M | 0 |
| GERALD AND ADELE KRAFT CHARITABLE FOUNDATION TR | Carmel | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $5.1M | 0 |
| Hillcrest Washington Youth Home Inc | Evansville | F30 Mental Health & Crisis Intervention | $5.1M | 3 |
| TIM AND LIBBY ASH FAMILY FOUNDATION INC | Fort Wayne | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $5.1M | 0 |
| WE BLOOM INC | Indianapolis | E70 Health Care | $5.1M | 1 |
| BEACON INC | Bloomington | B90 Education | $5.1M | 1 |
| BELIEVE CIRCLE CITY HIGH SCHOOL INC | Indianapolis | B29 Education | $5.1M | 2 |
