| YOUTH RIGHTS & JUSTICE | Portland | R99 Civil Rights, Social Action & Advocacy | $5.2M | 6 |
| NON-PROFIT TECHNOLOGY ENTERPRISE NETWORK | Portland | B99 Education | $5.2M | 1 |
| Wallowa Resources Inc | Enterprise | A99 Arts, Culture & Humanities | $5.2M | 1 |
| Community Helping Addicts Negotiate | Albany | F20 Mental Health & Crisis Intervention | $5.2M | 1 |
| EASTERN OREGON CENTER FOR | Ontario | P80 Human Services | $5.2M | 1 |
| Quadriplegics United Against Dependency | Portland | E50Z Health Care | $5.2M | 1 |
| USB IMPLEMENTERS FORUM INC | Beaverton | S41 Community Improvement & Capacity Building | $5.2M | 1 |
| BEND VISITOR & CONVENTION BUREAU | Bend | — | $5.2M | 1 |
| HOPE VILLAGE INC | Canby | P75Z Human Services | $5.2M | 1 |
| COASTAL HOME HEALTH & HOSPICE INC | Brookings | E92 Health Care | $5.1M | 5 |
| Family Solutions Inc | Ashland | — | $5.1M | 1 |
| ROGUE WORKFORCE PARTNERSHIP | Medford | J20 Employment | $5.1M | 2 |
| OREGON ECONOMIC DEVELOPMENT DISTRICTS | Enterprise | S30 Community Improvement & Capacity Building | $5.1M | 0 |
| TEACH-NW | Springfield | B29 Education | $5.1M | 2 |
| WALDORF ASSOCIATION OF PORTLAND INC | Milwaukie | B21Z Education | $5.1M | 7 |
| WORKFORCE INVESTMENT COUNCIL OF | Oregon City | J20 Employment | $5.1M | 2 |
| Washington County Visitors Association | Beaverton | — | $5.1M | 1 |
| YOUTH RESOURCES INC | Portland | P300 Human Services | $5M | 2 |
| ASANTE FOUNDATION | Medford | E22 Health Care | $5M | 5 |
| UNITED WAY OF LANE COUNTY | Springfield | T70Z Philanthropy, Voluntarism & Grantmaking Foundations | $5M | 2 |
| JPR FOUNDATION INC | Ashland | B40Z Education | $5M | 1 |
| WESTERN LANE COMMUNITY FOUNDATION | Florence | — | $5M | 0 |
| OREGON CENTER FOR CREATIVE LEARNING | Medford | A52 Arts, Culture & Humanities | $5M | 1 |
| MAKE-A-WISH FOUNDATION | Portland | E86Z Health Care | $5M | 2 |
| COOS WATERSHED ASSOCIATION | Coos Bay | C320 Environment | $5M | 1 |
| Bob & Evelyn Dieringer Family Foundation | Milwaukie | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $4.9M | 0 |
| SPONSORS INC | Eugene | — | $4.9M | 7 |
| INTERNATIONAL BROTHERHOOD OF ELECTRICAL | Tangent | — | $4.9M | 13 |
| KLAMATH WATERSHED PARTNERSHIP | Klamath Falls | C20 Environment | $4.9M | 1 |
| COALITION OF OREGON SCHOOL | Salem | — | $4.9M | 4 |
| Pure Desire Ministries International | Troutdale | F60 Mental Health & Crisis Intervention | $4.9M | 2 |
| ALBINA VISION TRUST INC | Portland | S31 Community Improvement & Capacity Building | $4.9M | 1 |
| CLEAR CREEK MUTUAL TELEPHONE COMPANY | Oregon City | — | $4.9M | 8 |
| PETER BRITT GARDENS MUSIC AND ARTS | Medford | — | $4.9M | 2 |
| First Story | Bend | L20 Housing & Shelter | $4.8M | 0 |
| Every Kid Sports | Bend | N12 Recreation & Sports | $4.8M | 4 |
| LEAGUE OF OREGON CITIES | Salem | W20 Public & Societal Benefit | $4.8M | 6 |
| DESCHUTES DEFENDERS INC | Bend | I80Z Crime & Legal-Related | $4.8M | 7 |
| DUTCH BROS FOUNDATION | Grants Pass | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $4.8M | 0 |
| CANNON BEACH CONFERENCE CENTER | Cannon Beach | — | $4.8M | 1 |
| CONNECTED LANE COUNTY | Eugene | B90 Education | $4.8M | 1 |
| CENTRAL OREGON COLLECTIVE | Bend | P73Z Human Services | $4.8M | 2 |
| FAMILY TREE RELIEF NURSERY | Albany | I72 Crime & Legal-Related | $4.8M | 1 |
| LUMINA HOSPICE AND PALLIATIVE CARE | Corvallis | P74Z Human Services | $4.8M | 5 |
| ARCHBISHOP FRANCIS N BLANCHET SCHOOL | Salem | B250 Education | $4.8M | 1 |
| OREGON JEWISH COMMUNITY FOUNDATION | Portland | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $4.8M | 3 |
| Portland Village School | Portland | B29 Education | $4.8M | 3 |
| SECONDMUSE FOUNDATION | Lake Oswego | S80 Community Improvement & Capacity Building | $4.8M | 0 |
| WARM SPRINGS COMMUNITY ACTION TEAM | Warm Springs | S20 Community Improvement & Capacity Building | $4.8M | 1 |
| FUND FOR PORTLAND PUBLIC SCHOOLS | Portland | B03 Education | $4.8M | 0 |
