| CREARTE INC | San Juan | A25 Arts, Culture & Humanities | $1.8M | 0 |
| MCS FOUNDATION INC | San Juan | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $1.8M | 0 |
| VITRINA SOLIDARIA INC | San Juan | S30 Community Improvement & Capacity Building | $1.8M | 0 |
| FUNDACION MMM INC | San Juan | P81 Human Services | $1.8M | 0 |
| SOCIEDAD AMBIENTE MARINO | San Juan | B80 Education | $1.7M | 0 |
| UNIVERSIDAD TEOLOGICA DEL CARIBE IN | Trujillo Alto | B99 Education | $1.7M | 2 |
| HERMANITAS DE LOS ANCIANOS DESAMPARADOS INC | San Juan | P80 Human Services | $1.7M | 0 |
| Centro Criollo de Ciencias y Technologia Inc | Caguas | A50 Arts, Culture & Humanities | $1.7M | 1 |
| MOLECULAR SCIENCES RESEARCH CENTER INC | San Juan | U99 Science & Technology | $1.7M | 2 |
| DR LUIS BAEZ DIAZ BREAST CANCER FOUNDATION OF PUERTO RICO | San Juan | G32 Diseases, Disorders & Medical Disciplines | $1.7M | 0 |
| CORPORACION PARA EL FINANCIAMIENTO EMPRESARIAL DEL COMERCIO Y DE LAS COMUNIDADES | San Juan | S31 Community Improvement & Capacity Building | $1.7M | 4 |
| FAMILIES PLANNING ASSOCIATION OF PUERTO RICO | San Juan | — | $1.7M | 1 |
| COLEGIO SAN GABRIEL INC | San Juan | B24 Education | $1.7M | 0 |
| FUNDACION GOOD BUNNY INC | San Juan | T99 Philanthropy, Voluntarism & Grantmaking Foundations | $1.6M | 0 |
| KatherineJames Foundation | Dorado | T90 Philanthropy, Voluntarism & Grantmaking Foundations | $1.6M | 0 |
| MINISTERIO BUEN SAMARITANO MARC MARCOS A RIVERA CORDOVA INC | Manati | X21 Religion-Related | $1.6M | 1 |
| EL CORREDOR TECNO ECONOMICO DE PUERTO RICO Y EL CARIBE | Mayaguez | S30 Community Improvement & Capacity Building | $1.6M | 1 |
| CORPORACION DESARROLLO ECONOMICO DE SALUD Y VIVIENDA | Arecibo | L20 Housing & Shelter | $1.6M | 1 |
| LIGA DE CIUDADES DE PUERTO RICO | San Juan | S01 Community Improvement & Capacity Building | $1.6M | 0 |
| PUERTO RICO DOWN SINDROME FOUNDATION INC | San Juan | G25 Diseases, Disorders & Medical Disciplines | $1.6M | 0 |
| VICTUS PUERTO RICO INC | Ponce | S20 Community Improvement & Capacity Building | $1.6M | 0 |
| PUERTO RICO CONSORTIUM FOR CLINICAL INVESTIGATION INC | San Juan | H05 Medical Research | $1.6M | 8 |
| COLEGIO DE ABOGADOS DE P R | San Juan | S41 Community Improvement & Capacity Building | $1.5M | 1 |
| FUNDACION ROYAL ISABELA INC | San Juan | C99 Environment | $1.5M | 0 |
| MANATI ACADEMIA DISCIPULOS DE CRISTO INC | Manati | B24 Education | $1.5M | 0 |
| FORJANDO UN NUEVO COMIENZO CORP | Guaynabo | P20 Human Services | $1.5M | 1 |
| PRO VIVIENDAS III INC | San Juan | L40 Housing & Shelter | $1.5M | 1 |
| CARIB CHRISTIAN MINISTRIES INC | Aguadilla | X20 Religion-Related | $1.4M | 0 |
| LIGA ATLETICA INTERUNIVERSITARIA | San German | N40 Recreation & Sports | $1.4M | 0 |
| Casa de la Bondad Inc | Humacao | P430 Human Services | $1.4M | 1 |
| GAUDIUM ET SPES FOUNDATION INC | San Juan | T12 Philanthropy, Voluntarism & Grantmaking Foundations | $1.4M | 3 |
| HOGAR CUNA DE SAN CRISTOBAL INC | Caguas | I72 Crime & Legal-Related | $1.4M | 0 |
| Fundacion Luis G Fortuno Inc | San Juan | S01 Community Improvement & Capacity Building | $1.4M | 0 |
| WASHBURN SCHOOL INC | Ponce | B20 Education | $1.4M | 0 |
| Centro De Apoyo Para El Desarrollo De La Union Familiar Inc | San Juan | P40 Human Services | $1.3M | 0 |
| INSTITUTO PARA EL DESARROLLO SOCIO ECONOMICO Y DE VIVIENDA DE PR INC | Mayaguez | L20 Housing & Shelter | $1.3M | 1 |
| SOLO POR HOY | San Juan | I31 Crime & Legal-Related | $1.3M | 1 |
| AYUDA LEGAL PUERTO RICO INC | San Juan | M20 Public Safety, Disaster Preparedness & Relief | $1.3M | 1 |
| HTAS DE LOS ANCIANOS DESAMPARADOS HOGAR SAN JOSE | Hormigueros | E91 Health Care | $1.3M | 1 |
| CASA DE NINOS MANUEL FERNANDEZ JUNCOS INC | San Juan | — | $1.3M | 0 |
| Ryder Health Plan Inc | Humacao | E310 Health Care | $1.3M | 0 |
| HOGAR DE NINAS DE CUPEY INC | San Juan | P430 Human Services | $1.3M | 0 |
| LOLA RUN LIKE A LOLA INC | Carolina | N99 Recreation & Sports | $1.3M | 0 |
| PUNTA BORINQUEN GOLF AND COUNTRY CLUB INC | Aguadilla | N6A Recreation & Sports | $1.3M | 0 |
| APNI INC | San Juan | P20 Human Services | $1.3M | 3 |
| HOGAR ALBERGUE DE NINOS MALTRATADOS DE SAN GERMAN INC | San German | I73 Crime & Legal-Related | $1.2M | 1 |
| OBLATAS DEL SANTISIMO REDENTOR INC BO CERRO GORDO BAYAMON PR 00619 | Bayamon | I72Z Crime & Legal-Related | $1.2M | 1 |
| PRO BONO INC - VOLUNTEER SERVICES OF THE PR BAR ASSOCIATION | San Juan | — | $1.2M | 1 |
| CENTRO DE CUIDADO DIURNO HABAC | Anasco | P33 Human Services | $1.2M | 0 |
| ConprmetidosCorp | San Juan | S30 Community Improvement & Capacity Building | $1.2M | 1 |
