| PARENT HEART WATCH | Wilmington | G43 Diseases, Disorders & Medical Disciplines | $346k | 2 |
| Lighten Family Foundation | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $345k | 0 |
| MAMIE A WARREN SENIOR CENTER INC | Smyrna | P81Z Human Services | $345k | 0 |
| WILMINGTON CHILDREN'S CHORUS | Wilmington | A6B Arts, Culture & Humanities | $345k | 1 |
| The Struthers Family Foundation | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $344k | 0 |
| The RW Upson Family Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $344k | 0 |
| DELAWARE VOLUNTEER FIREMENS & LADIES | Harbeson | — | $343k | 0 |
| The Burt's Bees Greater Good Foundation | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $343k | 0 |
| KENT COUNTY ASSOCIATION OF REALTORS | Dover | S41 Community Improvement & Capacity Building | $342k | 0 |
| Meliorism Works Fund | Wilmington | T12 Philanthropy, Voluntarism & Grantmaking Foundations | $341k | 0 |
| Dr Irwin E and Cherie R Thompson Family | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $341k | 0 |
| THE RAMSEY MCCLUSKEY FAMILY FOUNDATION | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $341k | 2 |
| Carlo & Micl Schejola Foundation | Wilmington | T12 Philanthropy, Voluntarism & Grantmaking Foundations | $341k | 0 |
| EON Charitable Foundation | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $341k | 0 |
| BACCHIERI FOUNDATION | Greenville | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $341k | 0 |
| The Zankel Scala Family Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $340k | 2 |
| HIZ Foundation | Dover | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $340k | 0 |
| The Long Road Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $340k | 0 |
| UNITED CEREBRAL PALSY OF DELAWARE | Wilmington | — | $340k | 1 |
| 18220 Fund | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $339k | 0 |
| THE TRAUMA SURVIVORS FOUNDATION | Wilmington | F60 Mental Health & Crisis Intervention | $339k | 0 |
| WILMINGTON BALLET ACADEMY OF THE | Wilmington | A62 Arts, Culture & Humanities | $339k | 1 |
| WILLIAM T SPOONER | Lewes | — | $338k | 0 |
| Saturn Foundation Global | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $338k | 0 |
| The Sundancer Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $338k | 0 |
| Tortimaki Foundation | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $337k | 0 |
| Amicus Amico Foundation | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $337k | 0 |
| The Henderson Family Kingdom Collection | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $337k | 0 |
| BPOE #1903 | Dover | — | $337k | 2 |
| RENEE'S RESCUES INCORPORATED | Hockessin | D01 Animal-Related | $336k | 0 |
| LEGADO DE ESPERANZA FOUNDATION | Wilmington | — | $336k | 0 |
| James T Lee Foundation Inc | Wilmington | — | $336k | 0 |
| Wm Brian & Judith A Little Charitable Trust | Hockessin | — | $335k | 1 |
| Rosenblum Family Foundation | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $335k | 0 |
| The Shade Tree Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $334k | 0 |
| TIFF Charitable Foundation | Wilmington | T99 Philanthropy, Voluntarism & Grantmaking Foundations | $334k | 0 |
| COLONIAL CHAPTER OF THE | Newark | — | $334k | 1 |
| SUSSEX SHORES BEACH ASSOCIATION | Bethany Beach | — | $334k | 0 |
| The Intricate Knot Foundation Inc | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $334k | 0 |
| Rickard Family Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $333k | 0 |
| HOYT CHARITABLE FOUNDATION F SHERMAN HOYT & | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $333k | 0 |
| Daniel J Daou Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $333k | 0 |
| Delaware Soccer Officials Association | Yorklyn | — | $332k | 4 |
| DELAWARE ASSOCIATION OF SCHOOL | Dover | — | $332k | 1 |
| The Paul D Schurgot Foundation Inc | Wilmington | — | $331k | 0 |
| CONGRESSIONAL COMMUNITIES INC | Camden | — | $331k | 0 |
| Gerald & Janet Carrus Foundation | Wilmington | T60Z Philanthropy, Voluntarism & Grantmaking Foundations | $331k | 1 |
| DELAWARE MULTICULTURAL AND CIVIC ORGANIZ | Dover | P46 Human Services | $331k | 3 |
| The Andrea-Mennen Family Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $331k | 0 |
| THE ROYSO FOUNDATION | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $331k | 0 |