| Creative Testing Solutions | Tempe | AZ | $493.5M | 17 |
| NETWORK FOR GOOD | Washington | DC | $342.2M | 4 |
| NSF INTERNATIONAL | Ann Arbor | MI | $203.1M | 26 |
| GLOBAL EMPOWERMENT MISSION INC | Doral | FL | $162.9M | 1 |
| United Mission For Relief & Development | Washington | DC | $149.9M | 3 |
| THE BREAST CANCER RESEARCH | New York | NY | $117.4M | 12 |
| NATIONAL FIRE PROTECTION ASSOCIATION | Quincy | MA | $115.2M | 10 |
| CIVIL AIR PATROL INC | Maxwell Afb | AL | $108.6M | 9 |
| UNITED WAY FOR SOUTHEASTERN MICHIGAN | Detroit | MI | $93.1M | 9 |
| UNIVERSITY EMERGENCY MEDICAL | Buffalo | NY | $77.8M | 15 |
| HopeWest | Grand Junction | CO | $59.1M | 12 |
| E4E RELIEF LLC | Charlotte | NC | $50.7M | 17 |
| RETIREE RESOURCES CORPORATION | Knoxville | TN | $49.3M | 7 |
| OHIO MEDICAL TRANSPORTATION INC | Columbus | OH | $49M | 8 |
| ICNA RELIEF USA PROGRAMS INC | New Hyde Park | NY | $46.4M | 2 |
| NATIONAL SAFETY COUNCIL | Itasca | IL | $46.2M | 19 |
| CENTER FOR DISASTER PHILANTHROPY INC | Washington | DC | $42.9M | 7 |
| TEAM RUBICON INC | Los Angeles | CA | $40.4M | 7 |
| INSURANCE INSTITUTE FOR HIGHWAY SAFETY | Arlington | VA | $36.3M | 11 |
| THE ST BERNARD PROJECT INC | New Orleans | LA | $35.3M | 7 |
| CORE COMMUNITY ORGANIZED RELIEF EFFORT | Los Angeles | CA | $31.7M | 9 |
| EARTHSCOPE CONSORTIUM | Washington | DC | $30.4M | 12 |
| SOLDIERS' ANGELS | San Antonio | TX | $30.1M | 5 |
| National Security Technology Accelerator | Crane | IN | $28.7M | 3 |
| LifeFlight of Maine LLC | Bangor | ME | $28.3M | 2 |
| THE NATIONAL REGISTRY OF EMERGENCY | Columbus | OH | $27.9M | 11 |
| KPMG US FOUNDATION INC | Montvale | NJ | $26.5M | 0 |
| MUSLIM AID AMERICA | McLean | VA | $26.2M | 1 |
| HARRIS COUNTY EMERGENCY CORPS | Houston | TX | $25.8M | 14 |
| SECURE COMMUNITY NETWORK INC | Chicago | IL | $25.3M | 11 |
| REFINERY TERMINAL FIRE COMPANY | Corpus Christi | TX | $24.6M | 6 |
| Insurance Institute for Business & Home | Richburg | SC | $24.2M | 10 |
| AAA AMBULANCE SERVICE INC | Hattiesburg | MS | $23.9M | 1 |
| NATIONAL INSTITUTE OF BUILDING SCIENCES | Washington | DC | $23.4M | 8 |
| ALLIANCE SAFETY COUNCIL | Baton Rouge | LA | $23.3M | 13 |
| OREGON WORKER RELIEF | Portland | OR | $23.1M | 0 |
| PENDER EMS AND FIRE INC | Burgaw | NC | $21.4M | 11 |
| SIMON W WARDWELL FOUNDATION | Cranston | RI | $19.3M | 6 |
| INDUSTRIAL SAFETY TRAINING COUNCIL | Beaumont | TX | $19M | 5 |
| CALIFORNIA FIRE SAFE COUNCIL INC | Sacramento | CA | $18.7M | 5 |
| AIRBNBORG INC | San Francisco | CA | $18.6M | 0 |
| THE AMERICAN INDIA FOUNDATION | New York | NY | $18M | 6 |
| ALL HANDS AND HEARTS | Mattapoisett | MA | $16.4M | 6 |
| ASSOCIATION OF PUBLIC-SAFETY | Daytona Beach | FL | $16.1M | 7 |
| INTERNATIONAL ASSOCIATION OF FIRE CHIEFS | McLean | VA | $16.1M | 6 |
| Automotive Coalition for Traffic Safety | Leesburg | VA | $15.9M | 2 |
| GODS PIT CREW INC | Danville | VA | $15.3M | 1 |
| WORLD BICYCLE RELIEF NFP | Chicago | IL | $14.3M | 7 |
| SOUTHWEST IOWA REC | Corning | IA | $14.2M | 13 |
| BRIDGE TO TURKIYE | Chapel Hill | NC | $14.2M | 0 |
