| Camp Canaan | Rock Hill | O43 Youth Development | $1.7M | 0 |
| CONSERVATION VOTERS OF SC | Columbia | — | $1.7M | 1 |
| Boys Farm Inc | Newberry | — | $1.7M | 2 |
| GENERATIONS ALTERNATIVE | Simpsonville | I730 Crime & Legal-Related | $1.7M | 0 |
| LOWCOUNTRY PREGNANCY CENTER | North Charleston | E400 Health Care | $1.7M | 1 |
| The Columbia Urban League Inc | Columbia | P22Z Human Services | $1.7M | 1 |
| Charles Towne Montessori School | Charleston | — | $1.7M | 1 |
| ZION WORLD WIDE MISSIONS | Greenville | X200 Religion-Related | $1.7M | 1 |
| THE ZVEJNIEKS FOUNDATION OF SOUTH | Elgin | T11 Philanthropy, Voluntarism & Grantmaking Foundations | $1.7M | 0 |
| NAMI SOUTH CAROLINA | Columbia | — | $1.7M | 0 |
| DOWNTOWN PARTNERSHIP COMMITTEE | Spartanburg | W20 Public & Societal Benefit | $1.7M | 3 |
| EDUCATIONAL FOUNDATION OF USCL INC | Lancaster | B82Z Education | $1.7M | 0 |
| DORCHESTER HERITAGE CENTER INC | Saint George | A54 Arts, Culture & Humanities | $1.7M | 0 |
| GATES SCHOOL | Columbia | B29 Education | $1.7M | 0 |
| COLLINS HOME FAMILY MINISTRIES | Seneca | — | $1.7M | 1 |
| FPCRC Inc | Columbia | P750 Human Services | $1.7M | 0 |
| FLORENCE CRITTENTON PROGRAMS OF SC | Charleston | P450 Human Services | $1.7M | 1 |
| PALMETTO STATE TEACHERS ASSOCIATION | West Columbia | — | $1.7M | 4 |
| URBAN LEAGUE OF THE UPSTATE | Greenville | P22Z Human Services | $1.7M | 1 |
| MIDLANDS MIDDLE COLLEGE INC | West Columbia | B250 Education | $1.7M | 1 |
| CHILD EVANGELISM FELLOWSHIP OF SC | Columbia | O55Z Youth Development | $1.7M | 1 |
| AIKEN STEEPLECHASE | Aiken | T70 Philanthropy, Voluntarism & Grantmaking Foundations | $1.7M | 0 |
| CLIFFS VALLEY COMMUNITY | Greenville | L50 Housing & Shelter | $1.7M | 0 |
| WHOLESPIRE INC | Columbia | B99 Education | $1.7M | 1 |
| RURAL COMMUNITY WATER DISTRICT | Georgetown | — | $1.7M | 6 |
| Oasis of Hope Inc | Belton | P32 Human Services | $1.7M | 3 |
| DISABILITY RESOURCE CENTER | North Charleston | P82 Human Services | $1.7M | 1 |
| GOLDEN CORNER FOOD PANTRY | Seneca | P20 Human Services | $1.7M | 1 |
| SC Educational Communications Inc | Spartanburg | A320 Arts, Culture & Humanities | $1.7M | 2 |
| FRIENDS OF THE GREENVILLE ZOO INC | Greenville | D115 Animal-Related | $1.7M | 1 |
| Allendale County Rescue Squad Inc | Allendale | E620 Health Care | $1.7M | 4 |
| QUIXOTE FOUNDATION | Sumter | B11 Education | $1.6M | 0 |
| MCCORMICK COUNTY SENIOR CENTER | McCormick | P81Z Human Services | $1.6M | 0 |
| HOPE in Lancaster Inc | Lancaster | P60Z Human Services | $1.6M | 1 |
| ACADEMY OF HOPE INC | Conway | B29 Education | $1.6M | 1 |
| LODGE NO 2351 LOYAL ORDER OF MOOSE | Surfside Beach | — | $1.6M | 1 |
| CANCER SURVIVORS PARK ALLIANCE | Greenville | E01 Health Care | $1.6M | 1 |
| DAVIS FAMILY FOUNDATION INC | Greenwood | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $1.6M | 0 |
| THE CHANDLER SCHOOL | Greenville | B20 Education | $1.6M | 1 |
| OPERATION HOME INC | North Charleston | P81 Human Services | $1.6M | 1 |
| CHANGED LIVES MINISTRY INC | Moncks Corner | P20 Human Services | $1.6M | 0 |
| SALVATION OAKS RECOVERY COMMUNITY | Greenwood | F22 Mental Health & Crisis Intervention | $1.6M | 1 |
| HELPING AND LENDING OUTREACH | North Charleston | Y20 Mutual & Membership Benefit | $1.6M | 2 |
| THE TOBY CASSELS FOUNDATION | Lexington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $1.6M | 0 |
| SOUTH CAROLINA SHERIFFS' | Columbia | — | $1.6M | 1 |
| GREG MATHIS CHARTER HIGH SCHOOL | North Charleston | B29 Education | $1.6M | 1 |
| SUMTER UNITED MINISTRIES | Sumter | — | $1.6M | 1 |
| Spartanburg Humane Society Inc | Spartanburg | — | $1.6M | 2 |
| East Cooper Home Store Inc | Mt Pleasant | P29 Human Services | $1.6M | 0 |
| SERVE AND CONNECT | Columbia | P20 Human Services | $1.6M | 1 |
