| LIFELINE INTERNATIONAL INC | Hilton Head Island | X20Z Religion-Related | $212k | 1 |
| SOUTH CAROLINA FIRST STEPS TO | Greenwood | B012 Education | $212k | 1 |
| BEAUFORT ART ASSOCIATION | Beaufort | A510 Arts, Culture & Humanities | $211k | 0 |
| COMMUNITY CARE & COUNSELING OF AIKEN | Aiken | F60 Mental Health & Crisis Intervention | $211k | 0 |
| Zion Evangelistic & Care Ministries Inc | Sheldon | Q33 International, Foreign Affairs & National Security | $211k | 0 |
| RICHLAND COUNTY SHERIFF'S | Columbia | Z99 Unknown | $211k | 0 |
| RICHLAND EAST INC | West Columbia | Z99Z Unknown | $211k | 0 |
| Carolina Master Chorale Inc | Myrtle Beach | A6B Arts, Culture & Humanities | $211k | 1 |
| THE DARRELL AND ALICIA JACKSON FOUN | Simpsonville | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $210k | 0 |
| WREN YOUTH ASSOCIATION | Piedmont | N60 Recreation & Sports | $210k | 0 |
| SOUTH CAROLINA WILDLIFE PARTNERSHIP | Orangeburg | D30 Animal-Related | $210k | 1 |
| LITTLE RIVER BPO ELKS LODGE #2840 | Little River | — | $210k | 0 |
| MURRELLS INLET 2020 INC | Murrells Inlet | C500 Environment | $210k | 0 |
| CAROLINA HOUSING AND COMMUNITY DEVELOPMENT CORPORATION | Rock Hill | L20 Housing & Shelter | $210k | 0 |
| BARRIER ISLANDS LITTLE LEAGUE INC | Johns Island | N63 Recreation & Sports | $210k | 0 |
| FERMATA CLUB | Aiken | — | $209k | 0 |
| DENTAL COMMUNITY FELLOWSHIP | Charleston | X11 Religion-Related | $209k | 1 |
| REFUGE INTERNATIONAL INC | Gilbert | Q71 International, Foreign Affairs & National Security | $209k | 0 |
| COACHES 4 CHARACTER INC | Mt Pleasant | O50 Youth Development | $209k | 0 |
| NURMAY MISSIONS INC | Fort Mill | X20 Religion-Related | $209k | 2 |
| THE SOUTH CAROLINA JUNETEENTH FREEDOM FEST | Columbia | P20 Human Services | $209k | 3 |
| Live Oak Counseling Center | Columbia | F30Z Mental Health & Crisis Intervention | $209k | 1 |
| CHRISTIAN REVIVAL CHURCH | Greenville | X20 Religion-Related | $209k | 0 |
| LOWCOUNTRY EQUINE-ASSISTED PSYCHOTHERAPY | Wadmalaw | E60 Health Care | $209k | 1 |
| SOUTH CAROLINA SOCIETY OF OPHTHALMOLOGY INC | Lancaster | — | $208k | 1 |
| Cancer of Many Colors | Lexington | G30 Diseases, Disorders & Medical Disciplines | $208k | 0 |
| KNIGHTS OF COLUMBUS | Charleston | — | $208k | 0 |
| PAWS IN THE PANHANDLE RESCUE AND ADOPTION | Lancaster | D20 Animal-Related | $208k | 0 |
| KINDER FAMILY FOUNDATION INC | Simpsonville | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $208k | 0 |
| BEACH COWBOY FITNESS FOUNDATION | Mt Pleasant | N30 Recreation & Sports | $208k | 0 |
| BARNWELL IV INC | Barnwell | P700 Human Services | $208k | 0 |
| HOPE UNIVERSAL INC | Seneca | X20 Religion-Related | $208k | 0 |
| FRAZOR EVANGELISTIC ASSOCIATION | Greenville | X200 Religion-Related | $207k | 1 |
| Life In Abundance | Simpsonville | P20 Human Services | $207k | 1 |
| GEORGETOWN BULLDOG BOOSTER CLUB | Georgetown | — | $207k | 0 |
| SISK FOUNDATION | Greenville | — | $207k | 0 |
| UPPER SAVANNAH LAND TRUST | Greenwood | C34 Environment | $207k | 1 |
| CHRISTIANS FOR MESSIAH MINISTRIES | Rock Hill | X21 Religion-Related | $207k | 3 |
| THE GARDEN CLUB OF SOUTH CAROLINA INC | Columbia | C420 Environment | $207k | 0 |
| South Carolina Urban Entomology | Columbia | B11 Education | $207k | 0 |
| EDISTO HISTORICAL PRESERVATION | Edisto Island | A82Z Arts, Culture & Humanities | $207k | 1 |
| THE HELPING HANDS AND LOVING PAWS FOUNDATION | Rock Hill | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $206k | 0 |
| Bold Leadership Network | Greenville | W70 Public & Societal Benefit | $206k | 3 |
| Tulips Thrift Store | Bluffton | — | $206k | 0 |
| Simply Worship Inc | Simpsonville | X20 Religion-Related | $206k | 2 |
| NORTH CHARLESTON SC YOUTH RESISTANCE INC | North Charlestonn | O22 Youth Development | $206k | 0 |
| Independent Textile Rental Association Inc | Columbia | S41 Community Improvement & Capacity Building | $206k | 0 |
| HARVEST EDGE CORPORATION | Greenville | P32 Human Services | $206k | 0 |
| DRAGON BOAT CHARLESTON | Charleston | G30 Diseases, Disorders & Medical Disciplines | $206k | 1 |
| Veterans of Foreign Wars Post 445 | Charleston | — | $205k | 0 |
