| LOWCOUNTRY MARINE MAMMAL NETWORK | North Charleston | D30 Animal-Related | $244k | 1 |
| HEROES ON HORSEBACK | Bluffton | N20 Recreation & Sports | $244k | 1 |
| LAURENS COUNTY COMMUNITY FOUNDATION INC | Clinton | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $244k | 0 |
| The Trojan Club Inc | Rock Hill | — | $244k | 0 |
| DRAWING NEAR TO GOD INC | Mt Pleasant | X21 Religion-Related | $244k | 1 |
| SCAGO EDUCATIONAL FACILITIES CORPORATION FOR SPARTANBURG COUNTY SCHOOL DISTRICT 3 | Spartanburg | B112 Education | $243k | 0 |
| E CRAIG WALL SR FOUNDATION | Conway | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $243k | 0 |
| COMPREHENSIVE PSYCHIATRIC CARE SPECIALISTS | Charleston | E11 Health Care | $243k | 19 |
| REMBERT AREA COMMUNITY COALITION | Rembert | P20 Human Services | $243k | 1 |
| WEGOJA FOUNDATION | Columbia | B90 Education | $243k | 1 |
| SHRINERS INTERNATIONAL JAMIL SHRINERS GROUP RETURN | Columbia | — | $243k | 0 |
| Friends of Colleton County Animal Shelter | Walterboro | D112 Animal-Related | $243k | 0 |
| OPPORTUNITY HUB | Spartanburg | — | $242k | 0 |
| HORSE N AROUND TRC | Lancaster | P80 Human Services | $242k | 0 |
| SOUTH CAROLINA SPEECH-LANGUAGE- HEARING ASSOCIATION | Columbia | — | $242k | 0 |
| LORIS HISTORICAL SOCIETY ARCHIVES LIBRARIES & MUSEUM INC | Loris | A50 Arts, Culture & Humanities | $242k | 0 |
| Apartment Association of Greater Columbia | Columbia | — | $242k | 0 |
| GATEWAY TO THE ARMY ASSOCIATION | Columbia | A84 Arts, Culture & Humanities | $242k | 0 |
| BRIDGEWOOD APARTMENTS | Chesterfield | L99Z Housing & Shelter | $242k | 0 |
| FREEDOM READERS INC | Surfside Beach | B92 Education | $242k | 1 |
| SOUTH CAROLINA ACADEMY OF PHYSICIAN ASSISTANTS | Columbia | — | $242k | 0 |
| DOWNTOWN ORANGEBURG REVITALIZATION ASSOCIATION | Orangeburg | S30Z Community Improvement & Capacity Building | $242k | 0 |
| HYDROMISSIONS | Lexington | Q33 International, Foreign Affairs & National Security | $242k | 0 |
| GREER COMMUNITY OUTREACH CENTER INC | Greer | P20 Human Services | $242k | 0 |
| Historic Rock Hill | Rock Hill | A800 Arts, Culture & Humanities | $241k | 1 |
| ROCCO'S HEARTLAND RESCUE INC | Piedmont | D20 Animal-Related | $241k | 1 |
| HARVEST COMMUNITY SCHOOL | Summerton | B20 Education | $241k | 0 |
| BETHEL VOLUNTEER FIRE DEPT INC | Clover | — | $241k | 0 |
| ROTARY CLUB OF FIVE POINTS | Columbia | — | $241k | 0 |
| GREENWOOD TOROS SOCCER CLUB INC | Greenwood | N64 Recreation & Sports | $241k | 1 |
| SOUTH CAROLINA EARLY CHILDHOOD ASSOCIATION | Jackson | O99 Youth Development | $240k | 6 |
| SOUTH CAROLINA ATHLETIC ADMINISTRAT ASSOCIATION | Beaufort | B112 Education | $240k | 0 |
| THE LADIES' BENEVOLENT SOCIETY | Charleston | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $240k | 0 |
| South Carolina Daughters of the American Revolution | Camden | A800 Arts, Culture & Humanities | $240k | 0 |
| COMMUNITY RESOURCE CENTER | Summerville | P20 Human Services | $240k | 0 |
| JUMPSTART | Spartanburg | I40 Crime & Legal-Related | $240k | 1 |
| CHARLESTON COUNTY BAR ASSOCIATION | Charleston | — | $240k | 0 |
| DANIEL ISLAND CLUB EMPLOYEE FUND | Daniel Island | T21 Philanthropy, Voluntarism & Grantmaking Foundations | $240k | 0 |
| Fountain Inn All Sports Booster Club | Fountain Inn | B11 Education | $240k | 0 |
| CHRISTIAN COMMUNITY MINISTRIES OF KERSHAW COUNTY | Camden | X21Z Religion-Related | $240k | 1 |
| DELTA TAU DELTA FRATERNITY THETA ETA CHAPTER | Columbia | — | $239k | 0 |
| TRAVELERS REST FARMERS MARKET | Travelers Rest | K30 Food, Agriculture & Nutrition | $239k | 1 |
| LIFETIDES INSTITUTE | Ridgeland | C32 Environment | $239k | 2 |
| COUNTYBANK FOUNDATION | Greenwood | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $239k | 0 |
| NEW PERSPECTIVES MEDIA ASSC | Orangeburg | A30 Arts, Culture & Humanities | $239k | 1 |
| WARRIOR WOD FOUNDATION | Ravenel | F30 Mental Health & Crisis Intervention | $239k | 0 |
| PBC KIDZ ACADEMY INC | Pauline | B21 Education | $239k | 0 |
| VETERANS OF FOREIGN WARS OF THE US DEPT OF SC | Murrells Inlet | W30 Public & Societal Benefit | $239k | 0 |
| PAMPLICO RESCUE & AMBULANCE SERVICE | Pamplico | M41 Public Safety, Disaster Preparedness & Relief | $239k | 0 |
| BARNWELL IV INC | Barnwell | P700 Human Services | $239k | 0 |
