| NorthWestern Energy Master Welfare Benefit | Sioux Falls | — | $905k | 0 |
| SOUTH DAKOTA TELECOMMUNICATIONS | Pierre | — | $894k | 1 |
| Safe Harbor | Aberdeen | — | $888k | 2 |
| HRMC FOUNDATION | Huron | E39I Health Care | $886k | 0 |
| South Dakota Voters First | Sioux Falls | — | $883k | 0 |
| SOUTHEAST TECHNICAL COLLEGE FOUNDATION | Sioux Falls | B82 Education | $883k | 0 |
| SOUTH DAKOTA HALL OF FAME | Chamberlain | A500 Arts, Culture & Humanities | $877k | 1 |
| FRIENDS OF THE GOSS OPERA HOUSE INC | Watertown | S11 Community Improvement & Capacity Building | $872k | 1 |
| Orthopedic Institute Foundation | Tea | N40 Recreation & Sports | $869k | 0 |
| BIG SIOUX NURSERY INC | Watertown | C194 Environment | $867k | 2 |
| RUSHMORE CONSUMER CREDIT RESOURCE | Rapid City | P51 Human Services | $862k | 1 |
| Brookings Economic Development | Brookings | — | $862k | 1 |
| SIOUX EMPIRE COMMUNITY THEATRE INC | Sioux Falls | A65 Arts, Culture & Humanities | $860k | 0 |
| Joint Well Field Inc | Toronto | Y22 Mutual & Membership Benefit | $857k | 6 |
| Wegner Arboretum Society | Sioux Falls | A80 Arts, Culture & Humanities | $857k | 1 |
| CHRISTIAN LIFE MINISTRIES | Rapid City | P46Z Human Services | $854k | 1 |
| HARRISBURG BASEBALL ASSOCIATION INC | Harrisburg | N63 Recreation & Sports | $853k | 0 |
| WATERTOWN AREA UNITED WAY INC | Watertown | T70Z Philanthropy, Voluntarism & Grantmaking Foundations | $851k | 0 |
| WILD HORSE BUTTE COMMUNITY DEVELOPMENT CORPORATION | Martin | P28 Human Services | $850k | 3 |
| Boys and Girls Clubs of the Black Hills | Hill City | — | $848k | 0 |
| INDEPENDENT INSURANCE AGENTS OF | Ft Pierre | — | $848k | 1 |
| Aberdeen Area Convention and Visitors | Aberdeen | — | $847k | 2 |
| SOUTH DAKOTA GOLF ASSOCIATION | Sioux Falls | O50 Youth Development | $846k | 2 |
| FIRST LUTHERAN CHURCH FOUNDATION | Sioux Falls | — | $844k | 0 |
| HURON CHAMBER & VISITORS BUREAU | Huron | Z99 Unknown | $843k | 1 |
| Onward Learning | Martin | B21 Education | $839k | 1 |
| THE LINCOLN HIGH SCHOOL BANDPARENTS | Sioux Falls | O112 Youth Development | $838k | 0 |
| OCETI WAKAN (SACRED FIREPLACE) | Pine Ridge | — | $833k | 2 |
| IHANKTONWAN COMMUNITY COLLEGE | Marty | B42Z Education | $828k | 5 |
| GIVING HOPE INC | Sioux Falls | P20 Human Services | $827k | 1 |
| NATIONAL PANCREATIC CANCER | Rapid City | G30 Diseases, Disorders & Medical Disciplines | $826k | 0 |
| WEBSTER AREA DEVELOPMENT | Webster | S30 Community Improvement & Capacity Building | $821k | 0 |
| FURNITURE MISSION OF SOUTH DAKOTA | Sioux Falls | P20 Human Services | $816k | 1 |
| UNITED WAY AND VOLUNTEER SERVICES OF GREATER YANKT | Yankton | T70Z Philanthropy, Voluntarism & Grantmaking Foundations | $813k | 0 |
| HURON AMBULANCE INC | Huron | E62Z Health Care | $811k | 5 |
| ARROW EDUCATION FOUNDATION INC | Watertown | B112 Education | $809k | 0 |
| PIERRE ECONOMIC DEVELOPMENT CORPORATION | Pierre | — | $808k | 1 |
| WATERTOWN AREA CHAMBER OF COMMERCE | Watertown | — | $808k | 0 |
| SWAN LAKE CHRISTIAN CAMP ASSN | Viborg | P30 Human Services | $803k | 2 |
| HURON AREA SENIOR CENTER INC | Huron | P81Z Human Services | $803k | 0 |
| SUANNE BIG CROW MEMORIAL FOUNDATION | Pine Ridge | — | $797k | 1 |
| PATHWAYS SHELTER FOR THE HOMELESS | Yankton | P85 Human Services | $793k | 1 |
| BEEF LOGIC INC | Pierre | K40 Food, Agriculture & Nutrition | $785k | 0 |
| Catholic Family Services | Sioux Falls | P40Z Human Services | $784k | 1 |
| EL RIAD SHRINERS | Sioux Falls | Y40Z Mutual & Membership Benefit | $780k | 1 |
| MITCHELL AREA SAFEHOUSE INC | Mitchell | P43Z Human Services | $780k | 0 |
| MOUNT RUSHMORE AREA ASSOCIATION OF REALT | Spearfish | — | $777k | 1 |
| ASSOCIATION FOR PROTESTANT REFORMED EDUCATION | Sioux Falls | B90 Education | $776k | 0 |
| DAKOTA INDIAN FOUNDATION INC | Chamberlain | P84Z Human Services | $774k | 2 |
| South Dakota Discovery Center | Pierre | D500 Animal-Related | $773k | 0 |
