| South Dakota Trade Association | Sioux Falls | S41 Community Improvement & Capacity Building | $964k | 2 |
| SOUTH DAKOTA UPLAND OUTFITTERS ASSOCIATION | Kimball | S46 Community Improvement & Capacity Building | $963k | 0 |
| ENGELSMA FAMILY FOUNDATION | Sioux Falls | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $961k | 0 |
| NorthWestern Energy Welfare Benefit Trust | Sioux Falls | — | $959k | 0 |
| PANTHER CUBS ACADEMY | Platte | P33 Human Services | $958k | 0 |
| South Dakota Veterans Alliance Inc | Sioux Falls | W30 Public & Societal Benefit | $957k | 0 |
| Cornerstones Career Learning Center | Huron | J200 Employment | $955k | 1 |
| WESTSIDE PRESCHOOL AND DAYCARE | Rapid City | — | $940k | 0 |
| Journey On Inc | Rapid City | O50 Youth Development | $937k | 1 |
| VOICES AGAINST CANCER | Harrisburg | G30 Diseases, Disorders & Medical Disciplines | $936k | 0 |
| LNI | Rapid City | A23 Arts, Culture & Humanities | $934k | 11 |
| GIVING HOPE INC | Sioux Falls | P20 Human Services | $933k | 1 |
| Mary Chilton DAR Foundation | Sioux Falls | T90Z Philanthropy, Voluntarism & Grantmaking Foundations | $927k | 0 |
| United Way of Northeastern South Dakota Inc | Aberdeen | — | $922k | 1 |
| Aberdeen Development Corporation | Aberdeen | — | $921k | 1 |
| SIOUX FALLS YOUTH HOCKEY ASSOCIATION | Sioux Falls | Z99Z Unknown | $919k | 1 |
| RIVER CITY DOMESTIC VIOLENCE CENTER | Yankton | P43 Human Services | $915k | 1 |
| BIG SIOUX NURSERY INC | Watertown | C194 Environment | $915k | 2 |
| WOODLAWN CEMETERY ASSOCIATION | Sioux Falls | — | $906k | 7 |
| RAPID CITY FINE ARTS COUNCIL INC | Rapid City | A26Z Arts, Culture & Humanities | $905k | 0 |
| SOUTH DAKOTA TELECOMMUNICATIONS ASSOCIATION | Pierre | — | $894k | 1 |
| Safe Harbor | Aberdeen | — | $888k | 2 |
| South Dakota Voters First | Sioux Falls | — | $883k | 0 |
| OAYE LUTA OKOLAKICIYE | Rapid City | F21 Mental Health & Crisis Intervention | $883k | 1 |
| SOUTH DAKOTA HALL OF FAME | Chamberlain | A500 Arts, Culture & Humanities | $877k | 1 |
| Orthopedic Institute Foundation | Tea | N40 Recreation & Sports | $869k | 0 |
| SOUTH DAKOTA DENTAL ASSOCIATION | Pierre | — | $866k | 1 |
| RUSHMORE CONSUMER CREDIT RESOURCE CENTER | Rapid City | P51 Human Services | $862k | 1 |
| Brookings Economic Development Corporation | Brookings | — | $862k | 1 |
| SIOUX EMPIRE COMMUNITY THEATRE INC | Sioux Falls | A65 Arts, Culture & Humanities | $860k | 0 |
| Oceti Sakowin Community Academy | Rapid City | B20 Education | $856k | 1 |
| CHRISTIAN LIFE MINISTRIES | Rapid City | P46Z Human Services | $854k | 1 |
| HARRISBURG BASEBALL ASSOCIATION INC | Harrisburg | N63 Recreation & Sports | $853k | 0 |
| WATERTOWN AREA UNITED WAY INC | Watertown | T70Z Philanthropy, Voluntarism & Grantmaking Foundations | $851k | 0 |
| WILD HORSE BUTTE COMMUNITY DEVELOPMENT CORPORATION | Martin | P28 Human Services | $850k | 3 |
| Aberdeen Area Convention and Visitors Bureau Inc | Aberdeen | — | $847k | 2 |
| SOUTH DAKOTA GOLF ASSOCIATION JUNIOR GOLF FOUNDATION | Sioux Falls | O50 Youth Development | $846k | 2 |
| FIRST LUTHERAN CHURCH FOUNDATION | Sioux Falls | — | $844k | 0 |
| HURON CHAMBER & VISITORS BUREAU | Huron | Z99 Unknown | $843k | 1 |
| INDEPENDENT INSURANCE AGENTS OF SOUTH DAKOTA | Ft Pierre | — | $838k | 1 |
| THE LINCOLN HIGH SCHOOL BANDPARENTS ASSOCIATION | Sioux Falls | O112 Youth Development | $838k | 0 |
| CROOKS COMMUNITY CHILD CARE CENTER | Crooks | P33 Human Services | $837k | 0 |
| SOUTH DAKOTA FFA FOUNDATION INC | Bath | — | $836k | 0 |
| OCETI WAKAN (SACRED FIREPLACE) | Pine Ridge | — | $833k | 2 |
| Dakota Mainstem Regional Water System Inc | Madison | — | $829k | 1 |
| WEBSTER AREA DEVELOPMENT CORPORATION | Webster | S30 Community Improvement & Capacity Building | $821k | 0 |
| ALL ABOUT U ADOPTIONS INC | Sioux Falls | P31 Human Services | $821k | 1 |
| SWAN LAKE CHRISTIAN CAMP ASSN | Viborg | P30 Human Services | $816k | 2 |
| UNITED WAY AND VOLUNTEER SERVICES OF GREATER YANKT | Yankton | T70Z Philanthropy, Voluntarism & Grantmaking Foundations | $813k | 0 |
| Boys and Girls Clubs of the Black Hills | Hill City | — | $811k | 0 |
