| MAYO CLINIC GROUP RETURN | Rochester | E21 Health Care | $14B | 247 |
| Thrivent Financial for Lutherans | Minneapolis | — | $10.6B | 30 |
| MAYO CLINIC | Rochester | E21 Health Care | $7.4B | 58 |
| UCARE MINNESOTA | Minneapolis | E22Z Health Care | $6.2B | 31 |
| ALLINA HEALTH SYSTEM | Minneapolis | E210 Health Care | $5.9B | 47 |
| ECMC GROUP INC | Minneapolis | B02 Education | $5B | 24 |
| Fairview Health Services | Minneapolis | E210 Health Care | $4.7B | 32 |
| HEALTHPARTNERS INC | Minneapolis | — | $3.2B | 34 |
| HMO Minnesota | Saint Paul | — | $3.1B | 18 |
| PARK NICOLLET GROUP RETURN | St Louis Park | — | $2.2B | 20 |
| MEDICA HEALTH PLANS | Minnetonka | — | $1.8B | 5 |
| HENNEPIN HEALTHCARE SYSTEM INC | Minneapolis | E220 Health Care | $1.7B | 21 |
| GROUP HEALTH INC | Minneapolis | E310 Health Care | $1.5B | 53 |
| STRATACOR | Minneapolis | — | $1.2B | 30 |
| CHILDREN'S HEALTH CARE | Minneapolis | E240 Health Care | $1.1B | 26 |
| REGIONS HOSPITAL | Minneapolis | E220 Health Care | $1.1B | 22 |
| ST CLOUD HOSPITAL | St Cloud | E220 Health Care | $1B | 18 |
| NORTH MEMORIAL HEALTH CARE | Robbinsdale | E220 Health Care | $907.6M | 27 |
| UNIVERSITY OF MINNESOTA PHYSICIANS | Minneapolis | E300 Health Care | $902.9M | 21 |
| SMDC MEDICAL CENTER | Duluth | E220 Health Care | $701.8M | 14 |
| NATIONAL MARROW DONOR PROGRAM | Minneapolis | E65 Health Care | $666.7M | 15 |
| CENTRACARE HEALTH SYSTEM | St Cloud | E21 Health Care | $596.5M | 42 |
| ST LUKE'S HOSPITAL OF DULUTH | Duluth | E220 Health Care | $556.8M | 11 |
| University of St Thomas | St Paul | B430 Education | $537.1M | 19 |
| UNIVERSITY OF MINNESOTA FOUNDATION | Minneapolis | B110 Education | $524M | 14 |
| Healtheast St John's Hospital | Minneapolis | E220 Health Care | $521.8M | 25 |
| ST MARY'S MEDICAL CENTER | Duluth | E220 Health Care | $506.4M | 14 |
| THE TRAVELERS EMPLOYEE BENEFIT TRUST | St Paul | — | $472.2M | 0 |
| DELTA DENTAL OF MINNESOTA | Minneapolis | — | $433.5M | 25 |
| WINGS FINANCIAL CREDIT UNION | Apple Valley | — | $421.6M | 18 |
| ESSENTIA HEALTH | Duluth | E112 Health Care | $348.2M | 38 |
| RIDGEVIEW MEDICAL CENTER | Waconia | E220 Health Care | $333.3M | 26 |
| SECOND HARVEST HEARTLAND | Brooklyn Park | K31 Food, Agriculture & Nutrition | $309.2M | 11 |
| Gillette Children's Specialty Healthcare | Saint Paul | E240 Health Care | $305.8M | 16 |
| OLMSTED MEDICAL CENTER | Rochester | E220 Health Care | $304.8M | 12 |
| ST OLAF COLLEGE | Northfield | B420 Education | $299.9M | 19 |
| CENTRACARE CLINIC | St Cloud | E32Z Health Care | $299.5M | 20 |
| CARLETON COLLEGE | Northfield | B42Z Education | $279M | 14 |
| ST JOSEPH'S MEDICAL CENTER | Brainerd | E220 Health Care | $276M | 18 |
| MAPLE GROVE HOSPITAL CORPORATION | Maple Grove | E22 Health Care | $274.3M | 10 |
| INTERNATIONAL OPERATING ENGINEERS UNION | Bloomington | — | $270.6M | 5 |
| EDUCATIONAL CREDIT | Minneapolis | W600 Public & Societal Benefit | $265M | 11 |
| SCHOLARSHIP AMERICA INC | Minneapolis | B820 Education | $259.9M | 7 |
| CONNEXUS ENERGY | Ramsey | — | $259M | 23 |
| CARPENTERS AND JOINERS WELFARE FUND | Bloomington | — | $256.9M | 10 |
| Wells Fargo Foundation | Minneapolis | T21 Philanthropy, Voluntarism & Grantmaking Foundations | $256.3M | 0 |
| TRUSTONE FINANCIAL CREDIT UNION | Plymouth | — | $255.2M | 25 |
| Healtheast Woodwinds Hospital | Minneapolis | E220 Health Care | $241.9M | 18 |
| THE DULUTH CLINIC LTD | Duluth | E320 Health Care | $238.1M | 17 |
| DAKOTA ELECTRIC ASSOCIATION | Farmington | — | $231.6M | 25 |
