| I-Reach 2 Inc | Evansville | L22 Housing & Shelter | $1.9M | 1 |
| WYOMING FARM BUREAU FEDERATION | Laramie | — | $1.9M | 1 |
| THE GEORGE B STORER FOUNDATION INC | Jackson | — | $1.8M | 1 |
| LEGAL AID OF WYOMING INC | Cheyenne | I800 Crime & Legal-Related | $1.8M | 1 |
| WIND RIVER DEVELOPMENT FUND | Fort Washakie | S30 Community Improvement & Capacity Building | $1.8M | 1 |
| REACH FOUNDATION | Riverton | L21Z Housing & Shelter | $1.8M | 0 |
| JOE AND ARLENE WATT FOUNDATION INC | Sheridan | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $1.8M | 0 |
| COMMUNITY SAFETY NETWORK | Jackson | — | $1.7M | 0 |
| Boys & Girls Club of Central Wyoming | Casper | O11 Youth Development | $1.7M | 0 |
| Protection and Advocacy System Inc | Cheyenne | F00A Mental Health & Crisis Intervention | $1.7M | 4 |
| MEALS ON WHEELS OF CHEYENNE INC | Cheyenne | K36Z Food, Agriculture & Nutrition | $1.7M | 1 |
| WYOMING HIGH SCHOOL ACTIVITIES ASSOCIATI | Casper | B25I Education | $1.7M | 1 |
| PIONEER COUNSELING SERVICES INC | Evanston | F320 Mental Health & Crisis Intervention | $1.7M | 2 |
| Wyoming Assn of Non Profit Organizations | Cheyenne | T03 Philanthropy, Voluntarism & Grantmaking Foundations | $1.7M | 1 |
| NEWELL B SARGENT FOUNDATION | Worland | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $1.7M | 4 |
| CASPER AREA ECONOMIC DEVELOPMENT | Casper | — | $1.7M | 1 |
| SHERIDAN WYO RODEO INC | Sheridan | — | $1.7M | 0 |
| EPPSON CENTER FOR SENIORS INC | Laramie | P81Z Human Services | $1.7M | 0 |
| The Doug Coombs Foundation | Jackson | O50 Youth Development | $1.7M | 1 |
| THE HENRY A MCKINNELL FOUNDATION | Jackson | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $1.7M | 0 |
| GREATER WYOMING BIG BROTHERS | Laramie | — | $1.7M | 0 |
| THE VINE FOUNDATION | Casper | X99 Religion-Related | $1.7M | 0 |
| VERDAD FOUNDATION | Casper | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $1.6M | 0 |
| HOSPICE OF SWEETWATER COUNTY INC | Rock Springs | P74Z Human Services | $1.6M | 1 |
| Tentmakers Bible Mission Inc | LaGrange | X20 Religion-Related | $1.6M | 3 |
| Hole Food Rescue | Jackson | K30 Food, Agriculture & Nutrition | $1.6M | 1 |
| Senate Opportunity Fund | Cheyenne | — | $1.6M | 0 |
| The Opatrny Family Foundation | Jackson | — | $1.6M | 0 |
| MULEY FANATIC FOUNDATION OF WYOMING INC | Green River | C30 Environment | $1.6M | 2 |
| NION ROBERT THIERIOT FOUNDATION | Elk Mountain | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $1.6M | 2 |
| Montessori School of Cheyenne | Cheyenne | B21Z Education | $1.6M | 0 |
| GILLETTE COLLEGE FOUNDATION | Gillette | B11 Education | $1.6M | 1 |
| TROOPERS DRUM & BUGLE CORPS INC | Casper | A6CZ Arts, Culture & Humanities | $1.5M | 0 |
| THE ANDREW ALLEN CHARITABLE FOUNDATION | Cheyenne | T20Z Philanthropy, Voluntarism & Grantmaking Foundations | $1.5M | 3 |
| WYOMING STATE 4-H FOUNDATION | Laramie | — | $1.5M | 0 |
| INTERNATIONAL BROTHERHOOD OF ELECTRICAL | Casper | — | $1.5M | 7 |
| FRIENDS OF THE BRIDGER TETON | Jackson | C36 Environment | $1.5M | 1 |
| CIOS | Wilson | — | $1.5M | 3 |
| VOLUNTEERS OF AMERICA NORTHERN ROCKIES | Cheyenne | E11 Health Care | $1.5M | 2 |
| YELLOWSTONE BEHAVIORAL HEALTH FOUNDATION | Cody | F33 Mental Health & Crisis Intervention | $1.5M | 0 |
| LARAMIE INTERFAITH | Laramie | — | $1.5M | 0 |
| CHEYENNE REGIONAL AIR SERVICE FOCUS TEAM | Cheyenne | S20 Community Improvement & Capacity Building | $1.5M | 0 |
| The Art Association of Jackson Hole | Jackson | A400 Arts, Culture & Humanities | $1.5M | 2 |
| ORKEESWA INC | Pine Bluffs | P20 Human Services | $1.5M | 3 |
| NAGEL FAMILY FOUNDATION | Teton Village | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $1.5M | 0 |
| UKRAINE FREEDOM FUND | Afton | M12 Public Safety, Disaster Preparedness & Relief | $1.5M | 0 |
| GOSHEN COUNTY SENIOR FRIENDSHIP | Torrington | P81Z Human Services | $1.4M | 1 |
| Laramie Montessori School Inc | Laramie | B20 Education | $1.4M | 1 |
| NELSON FAMILY FOUNDATION | Wilson | — | $1.4M | 0 |
| Wyoming County Commissioners Association | Cheyenne | W20Z Public & Societal Benefit | $1.4M | 1 |
