| UNRIG OUR ECONOMY INC | Wilmington | — | $10.9M | 0 |
| John and Julie Schmidt Family Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $10.8M | 0 |
| NEIGHBORGOOD PARTNERS INC | Dover | K20Z Food, Agriculture & Nutrition | $10.8M | 1 |
| INTERCOLLEGIATE STUDIES INSTITUTE INC | Wilmington | B40Z Education | $10.7M | 6 |
| AIDS DELAWARE INC | Wilmington | E00A Health Care | $10.7M | 1 |
| The Whitcomb Family Foundation Inc | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $10.7M | 0 |
| CHEER INC | Georgetown | P810 Human Services | $10.6M | 3 |
| COLLIN AND JOANNA ROCHE FAMILY FOUNDATION | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $10.6M | 0 |
| Mackenzie Family Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $10.6M | 0 |
| THE VALOUR FOUNDATION | Dover | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $10.5M | 0 |
| The Jeffrey L Greenblum Charitable Foundation | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $10.5M | 0 |
| Pincus Family Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $10.4M | 0 |
| GE Vernova Foundation I | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $10.3M | 0 |
| REACH RIVERSIDE DEVELOPMENT CORP | Wilmington | L20 Housing & Shelter | $10.3M | 4 |
| MILFORD HOUSING DEVELOPMENT CORP | Milford | L210 Housing & Shelter | $10.3M | 0 |
| The Synopsys Foundation | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $10.2M | 0 |
| Dominique-Jean Larrey Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $10.2M | 0 |
| The Jay Farner Family Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $10.1M | 0 |
| DELAWARE BAR FOUNDATION | Wilmington | I128 Crime & Legal-Related | $10.1M | 1 |
| The RAATT DeJong Family Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $10.1M | 0 |
| Marin Senior Life Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $10M | 0 |
| Troopurr Foundation | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $10M | 0 |
| LONGVIEW PHILANTHROPY USA INC | Claymont | T05 Philanthropy, Voluntarism & Grantmaking Foundations | $10M | 5 |
| DELAWARE INNOVATION SPACE INC | Wilmington | S40 Community Improvement & Capacity Building | $10M | 4 |
| THE MINISTRY OF CARING INC | Wilmington | — | $10M | 2 |
| FREIRE CHARTER SCHOOL WILMINGTON INC | Wilmington | B29 Education | $9.9M | 2 |
| CHRISTIANA FIRE COMPANY INC | Christiana | — | $9.9M | 2 |
| LATIN AMERICAN COMMUNITY CENTER INC | Wilmington | P28Z Human Services | $9.9M | 1 |
| REHOBOTH BEACH COUNTRY CLUB | Rehoboth Beach | — | $9.8M | 9 |
| The Steedman Family Foundation | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $9.8M | 0 |
| FRIENDS OF DUCK CREEK REGIONAL LIBRARY | Smyrna | O20 Youth Development | $9.8M | 0 |
| Westminster Barrington Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $9.7M | 0 |
| The Georges J Daou Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $9.6M | 0 |
| The Tijori Foundation | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $9.6M | 2 |
| Mount Holly Charitable Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $9.6M | 0 |
| SELBYVILLE PUBLIC LIBRARY | Selbyville | — | $9.6M | 0 |
| Foundation for Truth Justice and Compassion | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $9.6M | 0 |
| The Linda and Mike Mussallem Foundation | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $9.5M | 0 |
| Tom Russell Charitable Foundation Inc | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $9.4M | 4 |
| THE BERNARD AND RUTH SIEGEL JEWISH COMMUNITY CENTER OF DELAWARE INC | Wilmington | — | $9.4M | 3 |
| Debra and Kenneth Caplan Foundation | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $9.3M | 0 |
| COMMUNITY EDUCATION BUILDING CORP | Wilmington | T23 Philanthropy, Voluntarism & Grantmaking Foundations | $9.2M | 1 |
| PLANNED PARENTHOOD DIRECT INC | Wilmington | E19 Health Care | $9.1M | 10 |
| The Dunn Foundation | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $9.1M | 2 |
| OPPORTUNITY CENTER INC | New Castle | — | $9.1M | 12 |
| Connolly Family Foundation Inc | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $9M | 0 |
| Walder Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $9M | 2 |
| INGLESIDE HOMES INC | Wilmington | P750 Human Services | $8.8M | 4 |
| The Lillian J Schauer Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $8.7M | 1 |
| DELAWARE MILITARY ACADEMY | Wilmington | B29 Education | $8.7M | 4 |
