| JOHNS HOPKINS UNIVERSITY | Baltimore | B430 Education | $10.5B | 35 |
| THE JOHNS HOPKINS HOSPITAL | Baltimore | E220 Health Care | $3.4B | 22 |
| A D F COMMUNITY OUTREACH FOUNDATION INC | Mechanicsville | T50 Philanthropy, Voluntarism & Grantmaking Foundations | $3.1B | 4 |
| Financial Industry Regulatory Authority Inc | Rockville | — | $2.6B | 41 |
| University of Maryland Medical System Corporation | Baltimore | E220 Health Care | $2.4B | 18 |
| HH MEDSTAR HEALTH INC | Columbia | E210 Health Care | $2.1B | 13 |
| Howard Hughes Medical Institute | Chevy Chase | H920 Medical Research | $1.8B | 33 |
| FINRA REGULATION INC | Rockville | — | $1.4B | 8 |
| AMERICAN POSTAL WORKERS UNION AFL CIO HEALTH | Elkridge | — | $1.3B | 24 |
| SINAI HOSPITAL OF BALTIMORE INC | Baltimore | E220 Health Care | $1B | 20 |
| JOHNS HOPKINS ALL CHILDREN'S HOSPITAL INC | Baltimore | E240 Health Care | $912.8M | 27 |
| ADVENTIST HEALTHCARE INC | Gaithersburg | — | $910.2M | 21 |
| IMPACTASSETSINC | Bethesda | T70 Philanthropy, Voluntarism & Grantmaking Foundations | $866.5M | 7 |
| JOHNS HOPKINS BAYVIEW MEDICAL CENTER INC | Baltimore | E220 Health Care | $805.6M | 16 |
| NECA IBEW FAMILY MEDICAL CARE TRUST FUND | Rockville | Y43 Mutual & Membership Benefit | $771M | 4 |
| HEALTHWELL FOUNDATION | Germantown | E99 Health Care | $742.4M | 19 |
| JOHNS HOPKINS HEALTH SYSTEM CORPORATION | Baltimore | E210 Health Care | $711.5M | 45 |
| HOLY CROSS HEALTH INC | Silver Spring | — | $709M | 17 |
| JACK AND NANCY DWYER WORKFORCE DEVELOPMENT CENTER INC | Baltimore | E91 Health Care | $696.1M | 6 |
| BOARD OF EDUCATION OF MONTGOMERY COUNTY EMPLOYEE BENEFIT TRUST FUND | Rockville | — | $690.1M | 0 |
| LUMINIS HEALTH ANNE ARUNDEL MEDICAL CENTER INC | Annapolis | E220 Health Care | $672.1M | 16 |
| Mercy Medical Center | Baltimore | E220 Health Care | $633.9M | 15 |
| MERITUS MEDICAL CENTER INC | Hagerstown | E220 Health Care | $633.6M | 14 |
| GREATER BALTIMORE MEDICAL CENTER INC | Baltimore | E220 Health Care | $629.2M | 20 |
| HENRY M JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE | Bethesda | H120 Medical Research | $628.9M | 13 |
| FRANKLIN SQUARE HOSPITAL CENTER INC | Baltimore | E220 Health Care | $613.1M | 14 |
| TIDALHEALTH PENINSULA REGIONAL INC | Salisbury | E220 Health Care | $575.5M | 12 |
| UMSJ Health System LLC | Towson | E11 Health Care | $568M | 14 |
| SOUTHERN MARYLAND ELECTRIC COOPERATIVE INC | Hughesville | W80Z Public & Societal Benefit | $542.5M | 28 |
| Baltimore Washington Medical Center Inc | Glen Burnie | E220 Health Care | $494.5M | 14 |
| JOHNS HOPKINS MEDICAL SERVICES CORPORATION | Baltimore | E220 Health Care | $490.3M | 10 |
| Dimensions Health Corporation | Upper Marlboro | E220 Health Care | $463.7M | 16 |
| THE UNION MEMORIAL HOSPITAL | Baltimore | E220 Health Care | $446.2M | 18 |
| Frederick Health Hospital Inc | Frederick | E220 Health Care | $425.5M | 26 |
| UPMC WESTERN MARYLAND CORPORATION | Cumberland | E20 Health Care | $407M | 12 |
| SUBURBAN HOSPITAL INC | Bethesda | E220 Health Care | $394.3M | 19 |
| Upper Chesapeake Medical Center Inc | Bel Air | E220 Health Care | $389.1M | 12 |
| NATIONAL AUTOMATIC SPRINKLER INDUSTRY WELFARE FUND | Landover | — | $385.6M | 13 |
| LOYOLA UNIVERSITY MARYLAND INC | Baltimore | — | $368.2M | 16 |
| MEDSTAR HEALTH INC | Columbia | E210 Health Care | $363.6M | 15 |
| LIFEBRIDGE HEALTH INC | Owings Mills | E210 Health Care | $358.9M | 17 |
| UNITED STATES PHARMACOPEIAL CONVENTION | Rockville | E050 Health Care | $357.7M | 13 |
| JHPIEGO CORPORATION | Baltimore | — | $349.7M | 22 |
| NFL PLAYER DISABILITY & SURVIVOR BENEFIT PLAN | Baltimore | — | $349.5M | 0 |
| HOWARD COUNTY GENERAL HOSPITAL INC | Baltimore | E220 Health Care | $333.9M | 14 |
| JOHNS HOPKINS COMMUNITY PHYSICIANS INC | Baltimore | — | $333.4M | 19 |
| SHEPPARD PRATT HEALTH SYSTEM INC | Baltimore | F310 Mental Health & Crisis Intervention | $319.6M | 14 |
| National Gallery of Art | Landover | A510 Arts, Culture & Humanities | $315.5M | 18 |
| CARROLL HOSPITAL CENTER INC | Westminster | E220 Health Care | $308.9M | 19 |
| Shore Health System Inc | Easton | E220 Health Care | $306.1M | 17 |
