| The 4D Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $5.6M | 0 |
| The Carol Moss Foundation | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $5.6M | 7 |
| The Nemec Abbott Foundation | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $5.6M | 0 |
| DEL-MAR-VA COUNCIL INC - BOY SCOUTS OF AMERICA | Dover | — | $5.6M | 2 |
| Al King Family Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $5.5M | 0 |
| MID ATLANTIC CLEAN HYDROGEN HUB INC | Dover | U12 Science & Technology | $5.5M | 3 |
| SMILOW FOUNDATION | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $5.5M | 4 |
| WEINGARTEN FOUNDATION | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $5.5M | 1 |
| Charles R Wood Foundation | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $5.5M | 0 |
| Broadcom Foundation | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $5.5M | 2 |
| Oechsle Family Foundation Inc | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $5.5M | 0 |
| Kevin M Jones Foundation Trust | Wilmington | T90 Philanthropy, Voluntarism & Grantmaking Foundations | $5.4M | 2 |
| MILL CREEK FIRE COMPANY INC | Wilmington | M24Z Public Safety, Disaster Preparedness & Relief | $5.4M | 0 |
| LITTLE SISTERS OF THE POOR INC | Newark | L22Z Housing & Shelter | $5.4M | 3 |
| Way Foundation Inc | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $5.4M | 0 |
| THE LIFE HEALTH CENTER COMPLEX INC | Wilmington | E30 Health Care | $5.3M | 2 |
| The Morris Foundation | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $5.3M | 0 |
| The Rhimes Foundation | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $5.3M | 0 |
| Sierra Pine Family Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $5.3M | 0 |
| FREEMAN ARTS PAVILION INC | Selbyville | A11 Arts, Culture & Humanities | $5.2M | 1 |
| F R BABCOCKBABCOCK UROLOGICAL ENDOW FD | Wilmington | B11 Education | $5.2M | 1 |
| PLANNED PARENTHOOD OF DELAWARE INC | Wilmington | E420 Health Care | $5.2M | 3 |
| The Francine A LeFrak Foundation Inc | Wilmington | T21 Philanthropy, Voluntarism & Grantmaking Foundations | $5.2M | 0 |
| READING ASSIST INSTITUTE | Wilmington | B90Z Education | $5.2M | 1 |
| Conservatives for Lower Health Care Costs Inc | Newark | — | $5.1M | 0 |
| PV Benevolence Foundation | Wilmington | P20 Human Services | $5.1M | 0 |
| Frank McHugh-O'Donovan Foundation Inc | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $5.1M | 0 |
| YWCA DELAWARE INC | Wilmington | P270 Human Services | $5.1M | 5 |
| CHILDREN'S BEACH HOUSE INC | Wilmington | — | $5.1M | 3 |
| INTERNATIONAL FOUNDATION FOR VALUING IMPACTS INC | Dover | V22 Social Science | $5.1M | 5 |
| GATEWAY CHARTER SCHOOL | Wilmington | B29 Education | $5M | 5 |
| Autism Delaware Inc | Newark | G84 Diseases, Disorders & Medical Disciplines | $5M | 1 |
| Firstfruits and Seeds Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $5M | 0 |
| The Foxwynd Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $5M | 0 |
| STK Foundation | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $5M | 0 |
| DOWNTOWN DOVER PARTNERSHIP CORPORATION | Dover | — | $5M | 0 |
| Nancy and Craig Stoller Family Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $5M | 0 |
| THE CEDARCREST CHARITABLE FOUNDATION AKA BLBB CHARITABLE | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $5M | 0 |
| Mitchell Family Foundation Inc | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $5M | 0 |
| MOISE Y SAFRA FOUNDATION INC | Wilmington | T23 Philanthropy, Voluntarism & Grantmaking Foundations | $5M | 0 |
| Lytton-Kambara Foundation | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $4.9M | 0 |
| David & Janet Polak Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $4.9M | 1 |
| WELFARE FOUNDATION INC | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $4.9M | 1 |
| FAITHFUL FRIENDS INC | New Castle | D20 Animal-Related | $4.9M | 3 |
| DELAWARE COLLEGE OF ART AND DESIGN | Wilmington | A60Z Arts, Culture & Humanities | $4.9M | 2 |
| WILMINGTON HEAD START INC | Wilmington | Z99 Unknown | $4.8M | 1 |
| LISA DEAN MOSELEY FOUNDATION | Rockland | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $4.8M | 0 |
| 2-4-3 Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $4.8M | 0 |
| JOBS FOR DELAWARE GRADUATES INC | Dover | J200 Employment | $4.8M | 2 |
| DELAWARE STANDARDBRED OWNERS ASSOCIATION INC | Dover | — | $4.8M | 1 |
