| FIRST STATE COMMUNITY ACTION AGENCY INC | Georgetown | — | $8.6M | 1 |
| COMMANDERIE D'AMERIQUE DE LA CONFRERIE DES CHEVALIERS DU TASTEVIN INC | Dover | N50 Recreation & Sports | $8.5M | 0 |
| Schuessler Family Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $8.5M | 0 |
| SOUTHBRIDGE MEDICAL ADVISORY COUNCIL INC | Wilmington | — | $8.4M | 7 |
| Shiff Family Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $8.4M | 0 |
| EARLY COLLEGE SCHOOL AT DELAWARE STATE UNIVERSITY | Dover | B25 Education | $8.4M | 4 |
| NEWARK EMERGENCY CENTER INC | Newark | E63Z Health Care | $8.4M | 15 |
| PEOPLES SETTLEMENT ASSOCIATION | Wilmington | — | $8.3M | 2 |
| The Christopher M Barnett Family Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $8.3M | 0 |
| ACADEMY OF DOVER CHARTER SCHOOL | Dover | B20 Education | $8.3M | 2 |
| PEOPLE'S PLACE II INC | Milford | P200 Human Services | $8.3M | 5 |
| Jonathan and Meredith Meeks Foundation | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $8.3M | 0 |
| SUSSEX COUNTY HABITAT FOR HUMANITY | Georgetown | — | $8.2M | 1 |
| DOERS NETWORK INC | Wilmington | — | $8.2M | 0 |
| EMMET FAMILY CHARITABLE FOUNDATION | Newark | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $8.2M | 2 |
| SYNGENTA VOL EMP BENEFICIARY TRUST | Wilmington | Y43 Mutual & Membership Benefit | $8.2M | 1 |
| NEW CASTLE COUNTY HEAD START INC | Newark | — | $8.2M | 1 |
| RODEL CHARITABLE FOUNDATION - DE | Wilmington | T11 Philanthropy, Voluntarism & Grantmaking Foundations | $8.1M | 5 |
| WEST END NEIGHBORHOOD HOUSE INC | Wilmington | — | $8.1M | 1 |
| DELAWARE ASSOC OF REHABILITATION FACILITIES CORP | Wilmington | P20Z Human Services | $8M | 2 |
| KINGS CREEK COUNTRY CLUB | Rehoboth Beach | — | $8M | 7 |
| The Michael and Karen Stone Family Foundation Inc | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $8M | 0 |
| Mortenson Company Foundation | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $7.9M | 0 |
| MLCOMMONS ASSOCIATION | Dover | S41 Community Improvement & Capacity Building | $7.8M | 0 |
| The Brent and Kathryn Wood Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $7.8M | 0 |
| HABITAT FOR HUMANITY OF NEW CASTLE COUNTY | Wilmington | — | $7.8M | 1 |
| KENT-SUSSEX INDUSTRIES INC | Milford | J300 Employment | $7.8M | 2 |
| THE KENDAL CORPORATION | Newark | E90 Health Care | $7.8M | 8 |
| The Schmetterling Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $7.7M | 0 |
| GRAND OPERA HOUSE INC | Wilmington | A800 Arts, Culture & Humanities | $7.7M | 2 |
| RUTH LILLY FOUNDATION | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $7.7M | 5 |
| JEWISH FEDERATION OF DELAWARE INC | Wilmington | — | $7.6M | 1 |
| Six String Giving Foundation | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $7.6M | 0 |
| TODMORDEN FOUNDATION | Wilmington | L22 Housing & Shelter | $7.6M | 0 |
| WILMINGTON CHRISTIAN SCHOOL INC | Hockessin | B24Z Education | $7.5M | 2 |
| THE PILOT SCHOOL INCORPORATED | Wilmington | — | $7.5M | 1 |
| The Pilgrim Foundation | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $7.5M | 2 |
| Edris Charitable Foundation | Wilmington | P99 Human Services | $7.5M | 0 |
| ST ANNE'S EPISCOPAL SCHOOL | Middletown | B240 Education | $7.5M | 3 |
| CHILD INC | Wilmington | P430 Human Services | $7.4M | 2 |
| RAJAM FAMILY FOUNDATION | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $7.4M | 0 |
| JEWISH FAMILY SERVICES OF DELAWARE INC | Wilmington | P40Z Human Services | $7.3M | 3 |
| SUSSEX MONTESSORI SCHOOL INC | Seaford | B20 Education | $7.3M | 3 |
| SEWELL C BIGGS TRUST THE BIGGS MUSEUM OF AMERICAN ART | Dover | A50 Arts, Culture & Humanities | $7.3M | 1 |
| Windhover Foundation Inc | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $7.2M | 0 |
| The Dorothy B Davis Foundation | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $7.2M | 2 |
| KENT COUNTY REGIONAL SPORTS COMPLEX | Frederica | N40 Recreation & Sports | $7.2M | 0 |
| Sunday Breakfast Mission Inc | Wilmington | — | $7.2M | 2 |
| Delaware Technology Park Inc | Newark | S20 Community Improvement & Capacity Building | $7.2M | 1 |
| Gift of Good Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $7.2M | 0 |