| The Brent and Kathryn Wood Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $7.9M | 0 |
| Amani Family Foundation | Wilmington | T21 Philanthropy, Voluntarism & Grantmaking Foundations | $7.9M | 0 |
| Mortenson Company Foundation | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $7.9M | 0 |
| MLCOMMONS ASSOCIATION | Dover | S41 Community Improvement & Capacity Building | $7.8M | 0 |
| The Passport Foundation | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $7.8M | 0 |
| HABITAT FOR HUMANITY OF NEW CASTLE | Wilmington | — | $7.8M | 1 |
| KENT-SUSSEX INDUSTRIES INC | Milford | J300 Employment | $7.8M | 2 |
| THE KENDAL CORPORATION | Newark | E90 Health Care | $7.8M | 8 |
| GRAND OPERA HOUSE INC | Wilmington | A800 Arts, Culture & Humanities | $7.7M | 2 |
| Sunday Breakfast Mission | Wilmington | — | $7.7M | 2 |
| SOUTHBRIDGE MEDICAL ADVISORY | Wilmington | — | $7.7M | 6 |
| JEWISH FEDERATION OF DELAWARE INC | Wilmington | — | $7.6M | 1 |
| Six String Giving Foundation | Wilmington | — | $7.6M | 0 |
| ST ANNE'S EPISCOPAL SCHOOL | Middletown | B240 Education | $7.6M | 3 |
| FIRST STATE MILITARY ACADEMY | Clayton | B29 Education | $7.6M | 2 |
| TODMORDEN FOUNDATION | Wilmington | L22 Housing & Shelter | $7.6M | 0 |
| KINGS CREEK COUNTRY CLUB | Rehoboth Beach | — | $7.5M | 5 |
| THE PILOT SCHOOL INCORPORATED | Wilmington | — | $7.5M | 1 |
| CHILD INC | Wilmington | P430 Human Services | $7.4M | 2 |
| JEWISH FAMILY SERVICES OF DELAWARE INC | Wilmington | P40Z Human Services | $7.3M | 3 |
| DELAWARE GUIDANCE SERVICES FOR CHILDREN | Wilmington | F32Z Mental Health & Crisis Intervention | $7.3M | 4 |
| SUSSEX MONTESSORI SCHOOL INC | Seaford | B20 Education | $7.3M | 3 |
| SEWELL C BIGGS TRUST THE BIGGS | Dover | A50 Arts, Culture & Humanities | $7.3M | 1 |
| Windhover Foundation Inc | Wilmington | — | $7.2M | 0 |
| KENT COUNTY REGIONAL SPORTS COMPLEX | Frederica | N40 Recreation & Sports | $7.2M | 0 |
| WILMINGTON CHRISTIAN SCHOOL INC | Hockessin | B24Z Education | $7.2M | 1 |
| Delaware Technology Park Inc | Newark | S20 Community Improvement & Capacity Building | $7.2M | 1 |
| Gift of Good Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $7.2M | 0 |
| THE WASILY FAMILY FOUNDATION INC | Wilmington | — | $7.1M | 2 |
| Gerri and Rich Wong Family Foundation | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $7.1M | 0 |
| AMER TR FOR OXFORD UNIV & EASTMAN 067381-000 | Wilmington | B43J Education | $7M | 1 |
| The Hylbert Family Foundation | Wilmington | P12 Human Services | $7M | 0 |
| SHEIN Foundation | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $7M | 0 |
| AETNA HOSE HOOK AND LADDER COMPANY | Newark | E62Z Health Care | $6.9M | 0 |
| WEST END NEIGHBORHOOD HOUSE INC | Wilmington | — | $6.9M | 1 |
| VICMEAD HUNT CLUB | Wilmington | — | $6.9M | 6 |
| ROBERT F STONE FOUNDATION AKA | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $6.9M | 1 |
| The Vincent Dowling Family Foundation Inc | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $6.9M | 0 |
| Bellingcat US Inc | Wilmington | B99 Education | $6.8M | 0 |
| ST ANTHONY'S COMMUNITY CENTER INC | Wilmington | P28Z Human Services | $6.7M | 1 |
| THE SAMUEL J & ETHEL LEFRAK | Wilmington | — | $6.7M | 0 |
| Norman R & L Racheal Gangestad Davis | Wilmington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $6.6M | 0 |
| DELAWARE ASSOCIATION OF CONSERVATION DIS | Dover | C030 Environment | $6.6M | 1 |
| RASKOB FOUNDATION FOR CATHOLIC | Wilmington | — | $6.6M | 1 |
| The Gerald D and Helen M Stephens | Wilmington | — | $6.5M | 0 |
| TUCC Inc | Wilmington | B12 Education | $6.5M | 3 |
| THE CARL M FREEMAN FOUNDATION INC | Selbyville | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $6.5M | 2 |
| DELAWARE STATE EDUCATION ASSOCIATION | Dover | — | $6.5M | 42 |
| WOUNDED WARRIOR PROJECT LT SUPPORT TRUST | Wilmington | P11 Human Services | $6.5M | 1 |
| TUSO | Wilmington | B11 Education | $6.5M | 2 |