| St Francis Animal Sanctuary Inc | Tylertown | D20 Animal-Related | $919k | 0 |
| PILGRIMAGE GARDEN CLUB INC | Natchez | — | $914k | 0 |
| MISSISSIPPI HEALTHCARE ALLIANCE INC | Jackson | E01 Health Care | $912k | 2 |
| HELLFIGHTERS INTERNATIONAL | Laurel | T11 Philanthropy, Voluntarism & Grantmaking Foundations | $909k | 0 |
| LIGHTHOUSE CHILDRENS HOMES INC | Kosciusko | P30 Human Services | $907k | 0 |
| FREE CLINIC OF MERIDIAN INC | Meridian | E21 Health Care | $904k | 0 |
| CASA OF NORTH MISSISSIPPI | Oxford | — | $904k | 1 |
| GLOBAL CONNECTIONS | Columbus | Q33 International, Foreign Affairs & National Security | $898k | 0 |
| MISSISSIPPI HERITAGE TRUST | Cleveland | A800 Arts, Culture & Humanities | $897k | 1 |
| HUMPHREY'S ACADEMY FOUNDATION | Belzoni | B24 Education | $897k | 0 |
| UNITED ASSOCIATION PLUMBERS | Vicksburg | — | $896k | 4 |
| GILMORE SANITARIUM INC | Amory | — | $895k | 0 |
| BROKEN LIVES MINISTRY | Nettleton | X99 Religion-Related | $894k | 2 |
| BOY SCOUTS OF AMERICA | Tupelo | — | $892k | 1 |
| GOOD HOPE WATER ASSOCIATION INC | Bassfield | — | $885k | 0 |
| Pearl River County SPCA | Picayune | D200 Animal-Related | $882k | 0 |
| MISSISSIPPI MINORITY FARMERS A | Okolona | K19 Food, Agriculture & Nutrition | $872k | 1 |
| MAGNOLIA MEDICAL FOUNDATION | Jackson | I43 Crime & Legal-Related | $870k | 0 |
| BILOXI YACHT CLUB | Biloxi | — | $869k | 0 |
| Copiah County Human Resource Agency | Hazlehurst | T30Z Philanthropy, Voluntarism & Grantmaking Foundations | $865k | 1 |
| Clinton Soccer Association Inc | Clinton | — | $865k | 3 |
| BOYS & GIRLS CLUB OF JACKSON CO | Moss Point | O23Z Youth Development | $862k | 1 |
| CALHOUN WATER ASSOCIATION | Laurel | Z99 Unknown | $862k | 0 |
| CAMP TANGLEWOOD INC | Brandon | X20 Religion-Related | $861k | 0 |
| KIDS HUB | Hattiesburg | F60 Mental Health & Crisis Intervention | $861k | 1 |
| CITY POINT WATER ASSOCIATION | Plantersville | W80 Public & Societal Benefit | $860k | 0 |
| CORNERSTONE FOUNDATION | Biloxi | Q300 International, Foreign Affairs & National Security | $857k | 2 |
| LEXIE WATER ASSOCIATION | Tylertown | Y22 Mutual & Membership Benefit | $854k | 0 |
| OKTIBBEHA COUNTY HUMANE SOCIETY INC | Starkville | D200 Animal-Related | $853k | 1 |
| LIFE CONSTRUCTION OUTREACH INC | Petal | X20 Religion-Related | $852k | 0 |
| SILOAM WATER DISTRICT INC | West Point | W80 Public & Societal Benefit | $852k | 0 |
| EMPOWERED FOR LIFE INC | Starkville | — | $851k | 1 |
| CHAPEL HILL HEIGHTS INC | Clarksdale | — | $851k | 1 |
| Mississippi Low-Income Childcare Initiative Inc | Biloxi | P30 Human Services | $848k | 1 |
| HUB WATER ASSOCIATION | Columbia | — | $845k | 0 |
| KAPPA DELTA SORORITY INC 0805 | Oxford | — | $844k | 0 |
| COLLINSVILLE WATER ASSOCIATION INC | Collinsville | Y22 Mutual & Membership Benefit | $840k | 0 |
| DELTA RESEARCH FOUNDATION | Stoneville | C053 Environment | $839k | 0 |
| WARRIOR BONFIRE PROJECT | Vicksburg | W30 Public & Societal Benefit | $837k | 0 |
| INTERNATIONAL BRO OF ELECTRICAL WORKERS | Pascagoula | — | $837k | 9 |
| LAMPTON WATER ASSOCIATION | Columbia | — | $836k | 0 |
| MS CENTER FOR POLICE & SHERIFFS | Raymond | I60 Crime & Legal-Related | $833k | 0 |
| ALL GODS CHILDREN CHILDCARE AND LEARNING CENTER | Nettleton | P33 Human Services | $831k | 1 |
| ST GABRIEL MERCY CENTER INC | Mound Bayou | P99 Human Services | $829k | 1 |
| JACKSON FUTBOL CLUB INC | Jackson | N64 Recreation & Sports | $829k | 4 |
| NORTH MISSINDUSTRIAL DEVELOPMENT A | West Point | — | $827k | 1 |
| HATTIESBURG AREA HABITAT FOR HUMANITY | Hattiesburg | — | $824k | 1 |
| ADMINISTRATIVE FUNDS EXTRA TABLE INC | Hattiesburg | K12 Food, Agriculture & Nutrition | $823k | 2 |
| LAKE PARK CEMETERY | Laurel | — | $822k | 1 |
| AMERICAN LEGION-POST 112 | Pearl | — | $822k | 0 |
