| Sacred Heart Health Ventures Inc | St Louis | — | $3.9M | 4 |
| THE PHOENIX FAMILY HOUSING CORPORATION | Kansas City | Z99 Unknown | $3.9M | 3 |
| CONNECTIONS TO SUCCESS | Stcharles | J99 Employment | $3.9M | 1 |
| CHILDREN'S CENTER FOR THE VISUALLY IMPAI | Kansas City | — | $3.9M | 1 |
| AFFTON ATHLETIC ASSOCIATION INC | Saint Louis | — | $3.9M | 0 |
| AIRCRAFT ELECTRONICS ASSOCIATION | Lees Summit | — | $3.9M | 3 |
| THRIVE ST LOUIS INC | St Louis | E400 Health Care | $3.8M | 1 |
| Alexian Brothers Bonaventure House | St Louis | — | $3.8M | 6 |
| KANSAS CITY CAMPUS FOR ANIMAL CARE | Kansas City | D20 Animal-Related | $3.8M | 0 |
| COVENANT HOUSE MISSOURI | St Louis | P300 Human Services | $3.8M | 3 |
| CIRCLE OF LIGHT ASSOCIATES | Saint Louis | S21Z Community Improvement & Capacity Building | $3.8M | 0 |
| THE INDEPENDENT LIVING CENTER INC | Joplin | A99 Arts, Culture & Humanities | $3.8M | 1 |
| VITAE FOUNDATION | Jefferson City | — | $3.8M | 3 |
| CIVIC CENTRAL CREDIT UNION | Jefferson City | — | $3.8M | 2 |
| CROSSROADS SCHOOL DBA CROSSROADS COLLEGE PREPARATORY SCHOOL | St Louis | — | $3.8M | 3 |
| Behavioral Health Network of Greater St | Saint Louis | E02 Health Care | $3.8M | 1 |
| MISSOURI BAPTIST FOUNDATION | Jefferson City | X12 Religion-Related | $3.8M | 2 |
| PERCEPTION FUNDING INC | Kansas City | X12 Religion-Related | $3.8M | 1 |
| LARCHE ST LOUIS | Brentwood | F33 Mental Health & Crisis Intervention | $3.8M | 1 |
| VICTORY BIBLE INSTITUTE | Joplin | X90 Religion-Related | $3.8M | 0 |
| GREEN HILLS COMMUNITY ACTION AGENCY | Trenton | P20Z Human Services | $3.8M | 1 |
| THE RACQUET CLUB | St Louis | — | $3.8M | 2 |
| ASSOCIATION OF RECORDS MANAGERS AND ADMINISTRATORS | Lees Summit | — | $3.7M | 3 |
| UPPER ROOM KC | Kansas City | N31 Recreation & Sports | $3.7M | 1 |
| THOMAS JEFFERSON SCHOOL | St Louis | — | $3.7M | 1 |
| RICHARDSON FAM ED TR ED MAIN | Saint Louis | B820 Education | $3.7M | 1 |
| GORDON PARKS ELEMENTARY SCHOOL | Kansas City | B300 Education | $3.7M | 1 |
| DCA FAMILY FOUNDATION | Clayton | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $3.7M | 0 |
| AMERICAN BOARD OF ORTHODONTICS | St Louis | — | $3.7M | 12 |
| CITY CREDIT UNION | Independence | — | $3.7M | 2 |
| Forvis Mazars Foundation | Springfield | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $3.7M | 0 |
| THE KITCHEN INC | Springfield | P200 Human Services | $3.7M | 1 |
| TRUMAN HERITAGE HABITAT FOR HUMANITY INC | Independence | — | $3.7M | 1 |
| VIA CHRISTI FOUNDATION INC | St Louis | — | $3.7M | 6 |
| THE ARC PROPERTY MANAGEMENT LLC | Springfield | P19 Human Services | $3.7M | 2 |
| CREDIT & HOMEOWNERSHIP EMPOWERMENT SERVICES | Kansas City | P51 Human Services | $3.7M | 2 |
| ALEXANDER MCCAUSLAND CHARITABLE | Saint Louis | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $3.7M | 1 |
| INDEPENDENT LIVING CENTER OF MID-MO | Columbia | E91 Health Care | $3.7M | 1 |
| SERVICE EMPLOYEES INTL UNION LOCAL 2000 HEALTH & WELFARE | St Louis | — | $3.7M | 1 |
| COLUMBIA MISSOURI INVESTMENT COMPANY | Columbia | — | $3.7M | 0 |
| CENTER FOR LIFE SOLUTIONS INC | Hazelwood | F20 Mental Health & Crisis Intervention | $3.7M | 0 |
| THE BAKEWELL FOUNDATION | Saint Louis | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $3.6M | 0 |
| CORNERSTONE CENTER FOR EARLY LEARNING | St Louis | — | $3.6M | 1 |
| MISSOURI TORAH INSTITUTE | Chesterfield | B25 Education | $3.6M | 3 |
| UNIVERSITY OF MISSOURI ALUMNI ASSOCIATION | Columbia | B840 Education | $3.6M | 1 |
| RICHARD W & PHYLLIS B DUESENBERG FOUNDATION | Clayton | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $3.6M | 0 |
| REFUGEE AND IMMIGRANT SERVICES & EDUCATION | Joplin | P84 Human Services | $3.6M | 1 |
| THE BIOME SCHOOL | Saint Louis | B29 Education | $3.6M | 2 |
| R C KEMPER JR CHARITABLE TRUST 10023600 | Kansas City | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $3.6M | 1 |
| Springfield Area Chamber of Commerce Inc | Springfield | — | $3.6M | 2 |
