| EDUCATIONAL FOUNDATION OF ALPHA GAMMA RHO | Kansas City | — | $3.6M | 2 |
| ST LOUIS ASSOCIATION OF REALTORS | St Louis | — | $3.6M | 3 |
| THE CHILD ADVOCACY CENTER INC | Springfield | I72 Crime & Legal-Related | $3.6M | 1 |
| FRIENDS OF THE ZOO OF KANSAS CITY FOUNDATION | Kansas City | D50 Animal-Related | $3.6M | 1 |
| UNITED INNER CITY SERVICES INC | Kansas City | P200 Human Services | $3.6M | 1 |
| API INNOVATION CENTER | Saint Louis | P20 Human Services | $3.6M | 4 |
| O'LOUGHLIN FAMILY FOUNDATION | St Louis | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $3.6M | 0 |
| RECOVERY LIGHTHOUSE INC | Warrensburg | F60 Mental Health & Crisis Intervention | $3.6M | 1 |
| MISSOURI UNITED METHODIST FOUNDATION INC | Columbia | — | $3.6M | 2 |
| GREATER KANSAS CITY SPORTS FOUNDATION | Kansas City | N60 Recreation & Sports | $3.6M | 1 |
| PI BETA PHI FRATERNITY ALABAMA BETA CHAPTER | Town Country | — | $3.6M | 0 |
| BOARD OF TRUSTEES OF ELECTRICIANS' INCOME SECURITY FUND | St Louis | — | $3.5M | 0 |
| MISSOURI ASSOCIATION OF AREA AGENCIES ON AGING | Jefferson City | — | $3.5M | 1 |
| CASS COMMUNITY HEALTH FOUNDATION | Kansas City | E129 Health Care | $3.5M | 2 |
| HABITAT FOR HUMANITY OF SPRINGFIELD INC | Springfield | L20Z Housing & Shelter | $3.5M | 1 |
| HUNT FAMILY FOUNDATION | Kansas City | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $3.5M | 0 |
| NATIONAL ASSOCIATION OF WORKFORCE DEVELOPMENT PROFESSIONALS | West Plains | S41 Community Improvement & Capacity Building | $3.5M | 3 |
| THE DRURY FAMILY CHARITABLE FOUNDATION | St Louis | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $3.5M | 0 |
| OUTREACH INTERNATIONAL | Kansas City | Q300 International, Foreign Affairs & National Security | $3.5M | 5 |
| WELCOME HOME INC | Columbia | — | $3.5M | 1 |
| SAINT LOUIS CLUB | St Louis | — | $3.5M | 4 |
| INDUSTRIAL AID INC | St Louis | J330 Employment | $3.5M | 1 |
| ASCENSION PROVIDENCE FOUNDATION | St Louis | P20 Human Services | $3.5M | 5 |
| EMIL BUEHLER PERPETUAL TRUST | Saint Louis | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $3.5M | 2 |
| HENRY COUNTY WATER COMPANY | Clinton | W80Z Public & Societal Benefit | $3.5M | 4 |
| EL Craig Foundation | Joplin | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $3.5M | 0 |
| MEMBERS 1ST CREDIT UNION | St Louis | — | $3.5M | 1 |
| ASCENSION BORGESS FOUNDATION | St Louis | — | $3.5M | 8 |
| Painting and Decorating Contractors | Maryland Heights | — | $3.5M | 3 |
| ST LOUIS PUBLIC SCHOOLS FOUNDATION | St Louis | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $3.4M | 1 |
| RACQUET CLUB LADUE | St Louis | — | $3.4M | 2 |
| WINGS OF HOPE | Saint Louis | Q193 International, Foreign Affairs & National Security | $3.4M | 2 |
| ASTHMA & ALLERGY FOUNDATION OF AMERICA ST LOUIS CHAPTER | Saint Louis | G45 Diseases, Disorders & Medical Disciplines | $3.4M | 1 |
| RONALD MCDONALD HOUSE CHARITIES OF MID MISSOURI INC | Columbia | E86Z Health Care | $3.4M | 1 |
| SETON CENTER INC | Kansas City | — | $3.4M | 1 |
| FLANCE MANAGEMENT INC D/B/A FLANCE EARLY LEARNING CENTER | St Louis | P20 Human Services | $3.4M | 1 |
| MIAA MO INC | Kansas City | N70 Recreation & Sports | $3.4M | 2 |
| ST ANDREW'S AT HOME SERVICES LLC | St Louis | P44 Human Services | $3.4M | 5 |
| LOST VALLEY LAKE RESORT CLUB INC | Owensville | N50 Recreation & Sports | $3.4M | 0 |
| TW M H JUDD CHARITABLE TRUST | Saint Louis | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $3.4M | 1 |
| FOUNDATION CREDIT UNION | Springfield | — | $3.4M | 1 |
| R C KEMPER CHARITABLE TRUST 10017800 | Kansas City | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $3.4M | 4 |
| OUR LADYS INN | St Louis | P450 Human Services | $3.4M | 4 |
| JOPLIN AREA HABITAT FOR HUMANITY I | Joplin | — | $3.4M | 0 |
| UNLIMITED PLAY INC | St Peters | P80 Human Services | $3.4M | 1 |
| SOUTHAMPTON COMMUNITY HEALTHCARE | Saint Louis | E32 Health Care | $3.4M | 0 |
| ELECTRICAL JOINT APPRENTICESHIP AND TRAINING TRUST FUND | Kansas City | — | $3.4M | 6 |
| MISSOURI COMMUNITY ACTION NETWORK | Jefferson City | P99 Human Services | $3.4M | 1 |
| POLICE FOUNDATION OF KANSAS CITY | Kansas City | I116 Crime & Legal-Related | $3.4M | 1 |
| PAWSPERITY INC | Kansas City | P99 Human Services | $3.4M | 2 |
