| DAILY BREAD MINISTRIES INC | Greer | — | $282k | 0 |
| CHRISTIANS TEACHING CHRISTIANS | Moore | X99 Religion-Related | $282k | 2 |
| O PERRY EARLE JR & LOUISE JORDAN EARLE F FOUNDATION C/O O PERRY EARLE III TRUSTE | Fountain Inn | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $282k | 0 |
| KAPPA ALPHA ORDER DELTA OMICRON CHAPTER | Clemson | — | $281k | 0 |
| Girls on the Run Upstate SC | Spartanburg | O22 Youth Development | $281k | 2 |
| TRs Cancer Fighters Inc | North Myrtle Beach | H30 Medical Research | $281k | 0 |
| GOVERNMENT FINANCE OFFICERS ASSOCIATION OF PENNSYLVANIA | Charleston | B99 Education | $280k | 0 |
| RE-LAUNCH MINISTRIES INC HASTINGS | Anderson | X20 Religion-Related | $280k | 1 |
| CHRISTIAN HOPE ACADEMY INC | Gaston | B20 Education | $280k | 1 |
| ChildSmiles Dental Inc | Mullins | E30 Health Care | $280k | 0 |
| FREEDOM THAT LASTS MINISTRIES | Piedmont | P46 Human Services | $280k | 1 |
| EVERYDAY MISSION TRIP EVANGELISM ORGANIZATION | Okatie | X20 Religion-Related | $279k | 3 |
| GEORGETOWN COUNTY FIRST STEPS TO SCHOOL READINESS PARTNERSHIP | Greenwood | — | $279k | 1 |
| THE LENS FOUNDATION | Mt Pleasant | S20 Community Improvement & Capacity Building | $279k | 0 |
| MARYS HOME CARE SERVICES INC | Hemingway | P75 Human Services | $279k | 0 |
| STRATFORD BANDS BOOSTER | Goose Creek | O11 Youth Development | $279k | 0 |
| GRASSY POND VOLUNTEER FIRE DEPARTME | Gaffney | M24Z Public Safety, Disaster Preparedness & Relief | $278k | 0 |
| SOUTH CAROLINA INFORMATION TECHNOLOGY DIRECTORS ASSOCIATION | Columbia | — | $278k | 0 |
| CHESTER COUNTY CHAMBER OF COMMERCE | Chester | S41 Community Improvement & Capacity Building | $278k | 1 |
| XAVIER BAEZ MINISTRIES INC | Irmo | X20 Religion-Related | $277k | 0 |
| FAIRFIELD COUNTY FIRST STEPS TO SCHOOL READINESS PARTNERSHIP | Greenwood | B012 Education | $277k | 0 |
| KAPPA ALPHA ORDER DELTA CHAPTER | Spartanburg | — | $277k | 0 |
| Students in the Word Inc | Pawleys Island | X20 Religion-Related | $277k | 1 |
| CHARLESTON COUNTY PARKS FOUNDATION INC | Charleston | A80 Arts, Culture & Humanities | $277k | 1 |
| BEYOND HOUSING | Greenville | — | $277k | 0 |
| THE CRAIG AND VICKI BROWN FOUNDATION | Greenville | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $276k | 0 |
| LEXINGTON CHRISTIAN COUNSELING | Lexington | F60 Mental Health & Crisis Intervention | $276k | 2 |
| DAUFUSKIE ISLAND INDEPENDENT SCHOOL | Daufuskie Island | B20 Education | $276k | 1 |
| STILL WATER MONTESSORI SCHOOL INC | Ladson | B21 Education | $276k | 1 |
| CHALLENGES INC SC | Piedmont | F21 Mental Health & Crisis Intervention | $276k | 1 |
| South Carolina Summer Dance Conservatory | Columbia | A62 Arts, Culture & Humanities | $276k | 1 |
| THE RESERVE AT LAKE KEOWEE COMMUNITY FOUNDATION | Sunset | S20 Community Improvement & Capacity Building | $276k | 0 |
| GULLAH GEECHEE HISTORIC NEIGHBORHOODS COMMUNITY DEVELOPMENT | Hilton Head Island | A82 Arts, Culture & Humanities | $275k | 0 |
| PALMETTO AGRIBUSINESS COUNCIL | Columbia | K20 Food, Agriculture & Nutrition | $275k | 0 |
| LUCEY CHARITABLE FOUNDATION INC | Mount Pleasant | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $275k | 0 |
| JASPER COUNTY FIRST STEPS TO SCHOOL READINESS PARTNERSHIP | Greenwood | — | $275k | 0 |
| SPIRIT OF SOUTH CAROLINA INC | Charleston | — | $274k | 0 |
| RALPH H JOHNSON AMERICAN LEGION POST 147 | Charleston | — | $274k | 0 |
| EDDLEMON CHILD DEVELOPMENT CENTER INC | Spartanburg | B24 Education | $274k | 2 |
| HOSPICE HOUSE OF GREENVILLE | Simpsonville | P74 Human Services | $274k | 1 |
| AHEPA 284 IV INC | Columbia | L20 Housing & Shelter | $274k | 0 |
| CAMP DISCOVERY AT HIS ACRES INC | Blythewood | — | $274k | 2 |
| MINISTRY OF OUTREACH TO SLAVIC TRIBES INC | Columbia | X90 Religion-Related | $274k | 2 |
| Faith Moves Mountains Foundation | Gilbert | X21 Religion-Related | $273k | 1 |
| PARTNERS FOR CHANGE OF THE CAROLINAS INC | Sumter | O50 Youth Development | $273k | 0 |
| Midlands Alliance for Better Transportation and Ro | Columbia | — | $272k | 0 |
| BOILERMAKERS AFL-CIO LOCAL 456 | Rock Hill | — | $272k | 2 |
| Greenville Area Parkinsons Society | Greenville | M40 Public Safety, Disaster Preparedness & Relief | $272k | 2 |
| WELLSPRING LIVING SC | Spartanburg | L80 Housing & Shelter | $271k | 0 |
| 34 WEST PRODUCTIONS | Mt Pleasant | A60 Arts, Culture & Humanities | $271k | 0 |
