| UNION COUNTY FIRST STEPS TO SCHOOL READINESS PARTNERSHIP | Greenwood | B012 Education | $270k | 1 |
| Saluda Shoals Foundation | Columbia | N30Z Recreation & Sports | $270k | 0 |
| American Subcontractors Association of South Carolina Inc | Lexington | S41 Community Improvement & Capacity Building | $270k | 1 |
| FAIFIELD COUNTY CHAMBER OF COMMERCE | Winnsboro | S41 Community Improvement & Capacity Building | $270k | 0 |
| VETS HELPING VETS ANDERSON | Anderson | W30 Public & Societal Benefit | $270k | 0 |
| THE WARD FOUNDATION | Hilton Head | T21 Philanthropy, Voluntarism & Grantmaking Foundations | $270k | 0 |
| GREEN SEA FLOYDS ATHL BOOSTER CLUB | Green Sea | N12 Recreation & Sports | $270k | 0 |
| MONDAY AFTER THE MASTERS MAM PRO-AM GOLF TOURNAMENT INC | Columbia | — | $269k | 0 |
| PHI GAMMA DELTA FRATERNITY CLEMSON UNIVERSITY | Clemson | — | $269k | 0 |
| BOILING SPRINGS YOUTH ATHLETIC ASSOCIATION C-3 | Boiling Springs | — | $269k | 0 |
| Iron Wolf Recovery Fitness | Charleston | — | $269k | 2 |
| FROG SONG FARM SANCTUARY INC | Hodges | D60 Animal-Related | $268k | 0 |
| CLEBE MCCLARY EVANGELISTIC ASSOCIATION | Pawleys Island | — | $268k | 0 |
| LEDYARDHARLOW FOUNDATION INC | Charleston | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $267k | 0 |
| Suzuki Academy of Columbia | Columbia | B28 Education | $267k | 1 |
| GREENVILLE SHERIFF'S FOUNDATION | Greenville | — | $267k | 4 |
| THE VILLAGE REPERTORY COMPANY | Charleston | A65 Arts, Culture & Humanities | $267k | 0 |
| THE MANNA HOUSE | Florence | — | $267k | 0 |
| IGLESIA CRISTO NUESTRO REY INC | Bluffton | X20 Religion-Related | $267k | 0 |
| WOMAN'S BAPTIST E & M CONVENTION OF SC INC | Columbia | — | $266k | 0 |
| UASC INTERNATIONAL | Columbia | B90 Education | $266k | 4 |
| HEALTHY GROWING LEADERS INC | Greer | X19 Religion-Related | $266k | 1 |
| SOUTH CAROLINA QUARTER HORSE ASSOCIATION | Lexington | K26 Food, Agriculture & Nutrition | $266k | 0 |
| IRMO LITTLE LEAGUE | Irmo | N63 Recreation & Sports | $266k | 0 |
| CENTERVILLE VOLUNTEER FIRE DEPT INC | Anderson | M24 Public Safety, Disaster Preparedness & Relief | $265k | 0 |
| SOUTH CAROLINA PUBLIC HEALTH ASSOCI | West Columbia | E70 Health Care | $265k | 0 |
| NORTH AUGUSTA CHAMBER OF COMMERCE | North Augusta | — | $265k | 1 |
| THE FRAZEE CENTER | Easley | B21 Education | $265k | 1 |
| CAROLINA MIRACLE LEAGUE INC | Spartanburg | P82 Human Services | $265k | 2 |
| DENNIS AND DEBORAH GETTER FOUNDATION | Fort Mill | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $264k | 0 |
| HOPE WOMENS CENTER INC | Easley | E400 Health Care | $264k | 1 |
| SECURITYS LENDING HAND FOUNDATION | Spartanburg | T22Z Philanthropy, Voluntarism & Grantmaking Foundations | $264k | 0 |
| QUAKER CEMETERY ASSOCIATION INC | Camden | — | $263k | 0 |
| THE HERITAGE LIBRARY FOUNDATION INC | Hilton Head Island | B70 Education | $263k | 1 |
| LOWCOUNTRY HOUSING & REDEVELOPMENT | Beaufort | L20 Housing & Shelter | $263k | 0 |
| Bright Side Youth Ranch Inc | York | N11 Recreation & Sports | $263k | 0 |
| SOUTH CAROLINA PRESS ASSOCIATION | Columbia | — | $263k | 2 |
| ARTS ETC | Johns Island | A12 Arts, Culture & Humanities | $263k | 0 |
| You Are The Power Foundation | Myrtle Beach | T40 Philanthropy, Voluntarism & Grantmaking Foundations | $262k | 7 |
| SEA PINES FOREST PRESERVE FOUNDATION | Hilton Head Island | A56Z Arts, Culture & Humanities | $262k | 2 |
| Tomorrows America Foundation Inc | Clover | — | $262k | 2 |
| ROTARY CLUB OF AIKEN FOUNDATION | Aiken | B82 Education | $261k | 0 |
| NORTH AUGUSTA YELLOW JACKET CLUB | North Augusta | N11 Recreation & Sports | $261k | 0 |
| NICHOLTOWN CHILD AND FAMILY COLLABORATIVE | Greenville | P40 Human Services | $261k | 1 |
| WE3 MISSIONS INC | Boiling Springs | P99 Human Services | $261k | 0 |
| KICKOFF SOCCER ACADEMY | Myrtle Beach | N60 Recreation & Sports | $260k | 0 |
| Leadership South Carolina | Columbia | B99 Education | $260k | 1 |
| GOING PLACES | Mount Pleasant | N99 Recreation & Sports | $260k | 1 |
| SOUTH CAROLINA FALUN DAFA ASSOCIATION | Greer | X50 Religion-Related | $260k | 0 |
| BEN'S FRIENDS | Charleston | F21 Mental Health & Crisis Intervention | $260k | 1 |
