| THE NEWBERRY MUSEUM | Newberry | A50 Arts, Culture & Humanities | $234k | 1 |
| MASTERWORKS CHOIR INC | Florence | — | $234k | 1 |
| AIKEN COMMUNITY THEATRE INC | Aiken | A650 Arts, Culture & Humanities | $234k | 0 |
| Goal Justice | Greenville | R01 Civil Rights, Social Action & Advocacy | $234k | 2 |
| 95 NETWORK NFP | Simpsonville | X02 Religion-Related | $234k | 2 |
| KEEP THE MIDLANDS BEAUTIFUL | West Columbia | C500 Environment | $234k | 1 |
| SOUTH CAROLINA FIRST STEPS TO | Greenwood | — | $233k | 0 |
| PINE HILL INDIAN COMMUNITY DEVELOPMENT INITIATIVE | Orangeburg | S20 Community Improvement & Capacity Building | $233k | 2 |
| GRACE CARES FOUNDATION | Spartanburg | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $233k | 0 |
| GREATER ROSEWOOD MERCHANTS ASSOCIATION | Columbia | S41 Community Improvement & Capacity Building | $233k | 0 |
| COMPREHENSIVE PSYCHIATRIC CARE | Charleston | E11 Health Care | $233k | 14 |
| MIRACLE LEAGUE OF FLORENCE COUNTY | Florence | N63 Recreation & Sports | $233k | 0 |
| FRIENDS OF MOMENTUM BIKE CLUBS | Greenville | O23 Youth Development | $233k | 0 |
| ABI INTERNATIONAL INC | Easley | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $232k | 0 |
| RICHLAND COUNTY PUBLIC EDUCATION | Columbia | B19 Education | $232k | 1 |
| NEW HOLLAND VOLUNTEER FIRE DEPARTMENT | Wagener | E62 Health Care | $232k | 0 |
| FOOTHILLS TRAIL CONSERVANCY INC | Greenville | — | $232k | 1 |
| STEVE AND MARYBETH ALLSOP VOICE OF HOPE | Bluffton | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $232k | 0 |
| THE SALUDA CHARITABLE FOUNDATION | West Columbia | Q127 International, Foreign Affairs & National Security | $232k | 0 |
| EXTRA MILE CLUB OF THE LOWCOUNTRY | Beaufort | N30 Recreation & Sports | $232k | 3 |
| BEACH BALL CLASSIC | Myrtle Beach | — | $232k | 0 |
| MARITIME ASSOCIATION OF SOUTH CAROLINA | North Charleston | — | $232k | 1 |
| ASSOCIATION OF CANCER CENTER | Charleston | H30 Medical Research | $232k | 0 |
| THE RAMABAI INDIA PROJECT | Mount Pleasant | P33 Human Services | $231k | 2 |
| HERITAGE INSTITUTE | Travelers Rest | F30 Mental Health & Crisis Intervention | $231k | 1 |
| South Carolina Summary Court Judges | Irmo | S40 Community Improvement & Capacity Building | $231k | 0 |
| PEE DEE HOUSING DEVELOPMENT CORPORATION | Florence | — | $231k | 0 |
| CHESCO SERVICES | Chesterfield | P82Z Human Services | $231k | 0 |
| FREEWHEELERS CYCLING ASSOCIATION | Spartanburg | N99 Recreation & Sports | $230k | 0 |
| PHICAS FOUNDATION TRUST | Mt Pleasant | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $230k | 0 |
| SOUTH CAROLINA DIALOGUE FOUNDATION | Greenville | S01 Community Improvement & Capacity Building | $230k | 0 |
| Ebenezer Social Action & Community Development | Charleston | P70 Human Services | $230k | 0 |
| ARTS ETC | Johns Island | A12 Arts, Culture & Humanities | $230k | 0 |
| East Clarendon Athletic Booster Clu | Turbeville | B11 Education | $230k | 0 |
| HUMANE SOCIETY OF CHEROKEE COUNTY | Gaffney | D200 Animal-Related | $229k | 0 |
| SC CHAMBER EDUCATION AND | Columbia | — | $229k | 0 |
| INJURED WORKERS' ADVOCATES | Columbia | — | $229k | 0 |
| FURMAN FUTURE | Greenville | O50 Youth Development | $229k | 0 |
| LAURENS COUNTY MUSEUM ASSOCIATION | Laurens | A50 Arts, Culture & Humanities | $229k | 1 |
| COVENANT CHRISTIAN ACADEMY | North Augusta | B24 Education | $228k | 0 |
| BEAUFORT-JASPER COUNTY REALTORS INC | Beaufort | — | $228k | 0 |
| SOUTH CAROLINA ALLIANCE OF BLACK SCHOOL EDUCATORS | Columbia | B03 Education | $228k | 4 |
| SOUTH CAROLINA FIRST STEPS TO | Greenwood | B012 Education | $228k | 1 |
| South Carolina Pride Movement Inc | Columbia | A23 Arts, Culture & Humanities | $228k | 0 |
| J R ALBERT CHARITABLE TRUST | Charleston | T90 Philanthropy, Voluntarism & Grantmaking Foundations | $227k | 1 |
| SOUTH AIKEN HIGH SCHOOL ATHLETIC BOOSTER CLUB INC | Aiken | N41I Recreation & Sports | $227k | 0 |
| RABIEJ LITIGATION LAW CENTER | Hilton Head Island | B03 Education | $227k | 3 |
| MOTHER DEVEAUX ADULT DAY CARE | Eastover | — | $227k | 2 |
| Moultrie Middle School PTO | Mount Pleasant | B12 Education | $226k | 0 |
| BGM INC | Greenville | F60 Mental Health & Crisis Intervention | $226k | 0 |
