| South Dakota Soybean Association | Sioux Falls | — | $673k | 1 |
| LAKE OAHE LEARNING ACADEMY | Mobridge | O20 Youth Development | $672k | 0 |
| WESTERN RESOURCES FOR INDEPEND | Rapid City | P80Z Human Services | $671k | 1 |
| NECOG Development Corporation | Aberdeen | W60 Public & Societal Benefit | $665k | 7 |
| BLACK HILLS CHILDREN'S RANCH INC | Rapid City | P51 Human Services | $658k | 3 |
| WATERTOWN CONVENTION & VISITORS BUR | Watertown | S41 Community Improvement & Capacity Building | $654k | 1 |
| GREAT AFTER-SCHOOL PLACE | Brookings | B900 Education | $653k | 3 |
| SOUTH DAKOTA AGRICULTURAL FOUNDATION INC | Fort Pierre | K20 Food, Agriculture & Nutrition | $651k | 2 |
| MOBRIDGE ECONOMIC DEVELOPMENT CORPORATION | Mobridge | — | $650k | 0 |
| HARRISBURG COMMUNITY FOUNDATION | Harrisburg | P20 Human Services | $650k | 1 |
| PRAIRIE HISTORICAL SOCIETY INC | Madison | A82Z Arts, Culture & Humanities | $649k | 2 |
| RUTH A AND RAYMOND A REISTER CHARITABLE TRUST | Sioux Falls | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $649k | 3 |
| PIEDMONT EMERGENCY MEDICAL SERVICES | Piedmont | E62 Health Care | $649k | 4 |
| ARTS SOUTH DAKOTA INC C/O JIM SPEIRS | Sioux Falls | A20 Arts, Culture & Humanities | $648k | 0 |
| SOUTH DAKOTA VOICES FOR PEACE | Sioux Falls | — | $646k | 1 |
| SIOUX FALLS AREA CASA PROGRAM | Sioux Falls | R200 Civil Rights, Social Action & Advocacy | $645k | 1 |
| NATIVE WOMENS SOCIETY OF THE GREAT PLAINS RECLAIMING OUR SACREDNESS | Eagle Butte | P62 Human Services | $644k | 1 |
| He Sapa Otipi Inc | Rapid City | P20 Human Services | $642k | 2 |
| BROOKINGS AREA CHAMBER OF COMMERCE | Brookings | — | $641k | 1 |
| INDEPENDENT ELECTRICAL CONTRACTORS- DAKOTAS EDUCATION FUND | Sioux Falls | B50 Education | $637k | 0 |
| Indoor Football League | Sioux Falls | N80 Recreation & Sports | $635k | 1 |
| CHILDREN'S HOUSE MONTESSORI | Rapid City | B20 Education | $633k | 2 |
| HEIDELBERG THEOLOGICAL SEMINARY | Sioux Falls | B50 Education | $633k | 5 |
| MOVE THE MOUNTAIN LEADERSHIP CENTER | Rapid City | W707 Public & Societal Benefit | $632k | 1 |
| Stanley Post 20 of the American Legion | Fort Pierre | W30 Public & Societal Benefit | $630k | 0 |
| Brookings Ice Skating Association Inc | Brookings | — | $629k | 0 |
| VC MEDICAL ENDOWMENT TRUST | Sioux Falls | T90 Philanthropy, Voluntarism & Grantmaking Foundations | $629k | 0 |
| MOBRIDGE COUNTRY CLUB | Mobridge | — | $627k | 1 |
| SALEM MENNONITE HOME FOR THE AGED | Freeman | P75Z Human Services | $626k | 1 |
| SIOUX FALLS HOPE COALITION | Sioux Falls | P12 Human Services | $626k | 1 |
| Emilys Hope | Sioux Falls | P80 Human Services | $624k | 1 |
| SECOND CENTURY HABITAT FUND INC | Pierre | C30 Environment | $619k | 0 |
| WEBSTER 2020 INC | Webster | S30 Community Improvement & Capacity Building | $618k | 0 |
| SOUTH DAKOTA NEWS WATCH | Brookings | A33 Arts, Culture & Humanities | $611k | 1 |
| FORK REAL COMMUNITY CAFE INC | Rapid City | K30 Food, Agriculture & Nutrition | $610k | 1 |
| SOUTH DAKOTA ASSOCIATION OF COUNTY COMMISSIONERS | Pierre | — | $605k | 1 |
| HURON AREA WELLNESS AND RECREATION CENTER INC | Huron | N30 Recreation & Sports | $604k | 1 |
| BRANDON VALLEY BOOSTER CLUB INC | Brandon | B11 Education | $603k | 0 |
| Onward Learning | Martin | B21 Education | $603k | 2 |
| BROOKINGS CONVENTION & VISITORS BUREAU | Brookings | Y03 Mutual & Membership Benefit | $600k | 0 |
| ALLY DAKOTA DEVELOPMENT INC | Rapid City | — | $600k | 0 |
| THE MULTIFAMILY IMPACT COUNCIL | Sioux Falls | L03 Housing & Shelter | $592k | 0 |
| VETERANS OF FOREIGN WARS POST 3507 | Britton | — | $591k | 0 |
| FIRST DISTRICT DEVELOPMENT COMPANY | Watertown | S43Z Community Improvement & Capacity Building | $591k | 0 |
| HRMC FOUNDATION | Huron | E39I Health Care | $588k | 0 |
| CAROL CLARKSON EKLUND FOUNDATION PIONEER BANK & TRUST TRUSTEE | Belle Fourche | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $588k | 1 |
| ALCESTER INDUSTRIAL PARK INC | Alcester | — | $588k | 0 |
| VICTIMS OF VIOLENCE INTERVENTION | Spearfish | P43Z Human Services | $585k | 1 |
| BROOKINGS FUTBOL CLUB | Brookings | N64 Recreation & Sports | $585k | 0 |
| DELL RAPIDS AMBULANCE SERVICE | Dell Rapids | E62 Health Care | $584k | 1 |
