| BATTLE MOUNTAIN HUMANE SOCIETY | Hermosa | D20 Animal-Related | $581k | 2 |
| NORTHERN PRAIRIES LAND TRUST | Sioux Falls | C27 Environment | $581k | 1 |
| Storybook Island | Rapid City | — | $579k | 1 |
| LAKE REGION GOLF CLUB | Arlington | — | $574k | 0 |
| SOUTH DAKOTA AMATEUR HOCKEY ASSOCIATION | Watertown | O50 Youth Development | $574k | 1 |
| ASSOCIATED GENERAL CONTRACTORS OF SOUTH DAKOTA INC - BUILDING CHAPTER | Sioux Falls | — | $572k | 0 |
| VERENDRYE MUSEUM INC | Fort Pierre | — | $571k | 0 |
| BOYS & GIRLS CLUB OF THE MISSOURI RIVER AREA | Wagner | O23 Youth Development | $571k | 1 |
| SCULPTUREWALK INC | Sioux Falls | A40 Arts, Culture & Humanities | $570k | 0 |
| BASEBALL PARENTS INC | Rapid City | W30Z Public & Societal Benefit | $568k | 0 |
| SOUTH DAKOTA INSURANCE GUARANTY | Sioux Falls | — | $568k | 0 |
| LAKE AREA ZOOLOGICAL SOCIETY | Watertown | D115 Animal-Related | $567k | 0 |
| VASILIUS FAMILY FOUNDATION | Sioux Falls | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $567k | 0 |
| WALTER AND VIRGINIA HAGER FOUNDATION | Mobridge | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $563k | 0 |
| SOUTH DAKOTA HEALTH CARE COALITION | Harrisburg | E12 Health Care | $562k | 1 |
| SCHOOL ADMINISTRATORS OF SOUTH DAKOTA | Pierre | — | $561k | 1 |
| SHIFT GARAGE | Sioux Falls | P50 Human Services | $556k | 1 |
| MINNILUSA HISTORICAL ASSOCIATION | Rapid City | A82Z Arts, Culture & Humanities | $552k | 1 |
| FATTY ACID RESEARCH INSTITUTE | Sioux Falls | — | $551k | 1 |
| ELEVATE FOUNDATION INC | Rapid City | S30 Community Improvement & Capacity Building | $551k | 1 |
| BRITTON COUNTRY CLUB INC | Britton | — | $550k | 0 |
| CHANKU WASTE RANCH | Porcupine | P99 Human Services | $547k | 1 |
| CUSTER VOLUNTEER FIRE DEPARTMENT | Custer | — | $546k | 13 |
| CORN PALACE CITY POST 2750 VETERANS OF FOREIGN WARS | Mitchell | Y42 Mutual & Membership Benefit | $546k | 1 |
| WINGS OF VALOR INC | Parker | W30 Public & Societal Benefit | $544k | 0 |
| Restoration Generation Inc | Sioux Falls | I21 Crime & Legal-Related | $544k | 1 |
| TY ESCHENBAUM FOUNDATION | Sioux Falls | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $542k | 0 |
| GREATER HURON DEVELOPMENT CORPORATION AND SUBSIDIARIES | Huron | — | $541k | 1 |
| SOUTH DAKOTA STATE MEDICAL ASSOCIATION FOUNDATION | Sioux Falls | B54Z Education | $541k | 0 |
| SIOUX METRO GROWTH ALLIANCE | Sioux Falls | S30 Community Improvement & Capacity Building | $534k | 2 |
| HOMETOWN YOUTH SPORTS INC | Sioux Falls | O50 Youth Development | $534k | 0 |
| Lil Troopers Learning Center | Sioux Falls | P80Z Human Services | $533k | 0 |
| HARTFORD AREA FIRE & RESCUE INC | Hartford | M24 Public Safety, Disaster Preparedness & Relief | $532k | 0 |
| COMMUNITY OUTREACH | Sioux Falls | P600 Human Services | $530k | 3 |
| MITCHELL UNITED WAY | Mitchell | — | $529k | 1 |
| Sacred Mountain Retreat Center Inc | Deadwood | F33 Mental Health & Crisis Intervention | $529k | 1 |
| SOUTH DAKOTA AGRI-BUSINESS ASSOCIATION | Pierre | — | $529k | 2 |
| NATIONAL PANCREATIC CANCER FOUNDATION | Rapid City | G30 Diseases, Disorders & Medical Disciplines | $529k | 0 |
| RECREATION DEVELOPMENT ASSOCIATION | Elk Point | — | $528k | 0 |
| PLATTE DEVELOPMENT CORPORATION | Platte | S20Z Community Improvement & Capacity Building | $526k | 0 |
| STURGIS MOTORCYCLE MUSEUM & HALL OF FAME | Sturgis | A50 Arts, Culture & Humanities | $523k | 1 |
| SOUTH DAKOTA SPECIALTY PRODUCERS ASSOCIATION | Pierre | K20 Food, Agriculture & Nutrition | $522k | 0 |
| RAPID CITY SPORTS COMMISSION | Rapid City | — | $522k | 1 |
| LAKOTA YOUTH DEVELOPMENT | Herrick | F01 Mental Health & Crisis Intervention | $521k | 0 |
| THE KEYSTONE PROJECT INC | Keystone | X20 Religion-Related | $520k | 1 |
| GREAT PLAINS HOUSING INITIATIVE INC | Westport | L20 Housing & Shelter | $520k | 0 |
| LAKOTA COMMUNICATIONS INC | Porcupine | A34 Arts, Culture & Humanities | $520k | 6 |
| OBJECTIVE ZERO FOUNDATION | Sioux Falls | F40 Mental Health & Crisis Intervention | $519k | 1 |
| WATERTOWN FIGURE SKATE CLUB INC | Watertown | N70 Recreation & Sports | $519k | 0 |
| WINNER COUNTRY CLUB INC | Winner | — | $519k | 0 |
