| Psi of Alpha Phi House Corporation | Sioux Falls | — | $414k | 0 |
| CHRISTIAN SERVICE COUNCIL OF GRANT COUNTY | Milbank | — | $414k | 0 |
| American Legion Post 22 | Rapid City | — | $412k | 0 |
| SOUTH DAKOTA HIGH SCHOOL RODEO ASSOCIATI | Baltic | — | $411k | 0 |
| HEALTHCARE LAUNDRY ACCREDITATION COUNCIL | Rapid City | S41 Community Improvement & Capacity Building | $411k | 1 |
| VANTAGE POINT 3 MINISTRIES | Sioux Falls | X99 Religion-Related | $410k | 1 |
| PIPESTONE GIVE INC | Brandon | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $408k | 0 |
| PIONEER MEMORIAL MANORS INCORPORATED | Spearfish | — | $408k | 0 |
| BLACK HILLS CRISIS PREGNANCY CENTER | Rapid City | E40 Health Care | $406k | 0 |
| PHILIP SCOTTIES BOOSTER CLUB LLC | Philip | N50 Recreation & Sports | $403k | 0 |
| SOUTH DAKOTA DENTAL FOUNDATION | Pierre | E80 Health Care | $402k | 1 |
| SPURS Therapeutic Riding Center Inc | Aberdeen | E50Z Health Care | $402k | 3 |
| CITY OF REFUGE INC | Sioux Falls | Q33 International, Foreign Affairs & National Security | $401k | 1 |
| SIOUX FALLS FIGURE SKATING CLUB | Sioux Falls | N60Z Recreation & Sports | $399k | 0 |
| SOUTH DAKOTA ELECTRIC UTILITY COMPANIES | Pierre | — | $398k | 0 |
| FRIENDS OF BROOKINGS BASEBALL INC | Brookings | O99 Youth Development | $397k | 0 |
| THE TATANKA FUNDS INCORPORATED | Mission | S20 Community Improvement & Capacity Building | $397k | 1 |
| PAUL LOGAN MINISTRIES | Sioux Falls | X20 Religion-Related | $396k | 1 |
| INTERIOR VOLUNTEER FIRE DEPT | Interior | — | $394k | 4 |
| HISTORIC HOMESTAKE OPERA HOUSE SOCIETY | Lead | A80 Arts, Culture & Humanities | $393k | 2 |
| Days Of '76 Inc | Deadwood | — | $392k | 0 |
| SOUTH DAKOTA KNIGHTS OF COLUMBUS | Watertown | — | $391k | 1 |
| KEYA FOUNDATION LLC | Eagle Butte | B11 Education | $390k | 1 |
| MCCOOK LAKE IZAAK WALTON LEAGUE | North Sioux City | C300 Environment | $389k | 0 |
| FORT PIERRE VOLUNTEER FIRE FIGHTERS ASSOCIATION INC | Fort Pierre | — | $389k | 0 |
| WINDSWEPT ACADEMY INC | Eagle Butte | B24 Education | $388k | 0 |
| REACH LITERACY | Sioux Falls | — | $387k | 1 |
| BELLA PREGNANCY RESOURCE CENTER | Spearfish | E400 Health Care | $386k | 0 |
| EAST RIVER FOSTER PARENT NETWORK THE FOSTER NETWORK | Sioux Falls | P32 Human Services | $385k | 0 |
| CHILDREN'S CASTLE INC | Pierre | P33 Human Services | $384k | 1 |
| BOOTH SOCIETY INC | Spearfish | L80Z Housing & Shelter | $383k | 0 |
| PETERSON FAMILY FOUNDATION | Dakota Dunes | T20Z Philanthropy, Voluntarism & Grantmaking Foundations | $382k | 0 |
| VALLEY VIEW COUNTRY CLUB | Sisseton | — | $380k | 0 |
| AREAWIDE BUSINESS COUNCIL INCORPORATED | Yankton | — | $380k | 0 |
| EDWARD L SCHWAB MEMORIAL FOUNDATION DACOTAH BANK | Aberdeen | T20Z Philanthropy, Voluntarism & Grantmaking Foundations | $378k | 1 |
| CHURCH RESPONSE | Rapid City | P600 Human Services | $378k | 7 |
| LEADERSHIP SOUTH DAKOTA | Sioux Falls | B90 Education | $377k | 0 |
| INTERNATIONAL BROTHERHOOD OF ELECTRICAL WORKERS | Rapid City | — | $377k | 3 |
| MURDO GOLF CLUB | Murdo | N6A Recreation & Sports | $376k | 0 |
| BIG BROTHERS AND BIG SISTERS OF THE BLACK HILLS INC | Rapid City | — | $376k | 1 |
| SOUTH DAKOTA PLAYERS | Tea | N50 Recreation & Sports | $375k | 0 |
| BASEBALL 320 INC | Rapid City | N63 Recreation & Sports | $373k | 0 |
| AMERICAN LEGION AUXILIARY | Clear Lake | — | $373k | 3 |
| ELIZABETHS HOUSE OPTION 1 WOMENS HEALTH | Brookings | P45 Human Services | $370k | 1 |
| YANKTON COUNTY HISTORICAL SOCIETY | Yankton | A82Z Arts, Culture & Humanities | $368k | 0 |
| YANKTON RURAL AREA HEALTH EDUCATION CENTER | Yankton | E70Z Health Care | $367k | 1 |
| The Hatterscheidt Foundation Inc C/O Dacotah Bank Trust | Aberdeen | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $366k | 5 |
| LABORERS INTERNATIONAL UNION OF NORTH AMERICA LOCAL 620 | Sioux Falls | — | $366k | 1 |
| Brookings Regional Humane Society Inc | Brookings | D200 Animal-Related | $364k | 1 |
| SOUTH DAKOTA PETROLEUM MARKETERS AS | Pierre | — | $362k | 1 |
