| PRAIRIE HEART GUEST | Sioux Falls | E86 Health Care | $346k | 0 |
| FORT RANDALL RECREATION INC | Pickstown | — | $345k | 0 |
| BOOTH SOCIETY INC | Spearfish | L80Z Housing & Shelter | $345k | 0 |
| CRISIS INTERVENTION SHELTER SERVICE | Sturgis | P00L Human Services | $345k | 1 |
| MILBANK AREA CHAMBER OF COMMERCE | Milbank | — | $345k | 1 |
| WICONI WAWOKIYA INC | Fort Thompson | — | $345k | 1 |
| REGIONAL TECHNICAL EDUCATION | Yankton | B90 Education | $344k | 1 |
| WILD BIRD FEEDING INSTITUTE | Rapid City | — | $344k | 1 |
| MIDWEST EVANGELISTIC ASSOCIATION | Watertown | X20 Religion-Related | $342k | 0 |
| BEACON HILL RIFLE AND PISTOL CLUB | Volga | — | $341k | 0 |
| Faulkton Area Out of School Program | Faulkton | P33 Human Services | $341k | 1 |
| United States Bowling Congress | Rapid City | — | $341k | 0 |
| HUMAN SERVICE AGENCY FOUNDATION | Watertown | — | $341k | 0 |
| PHILIP AMBULANCE SERVICE | Philip | E62 Health Care | $341k | 0 |
| BEADLE AND SPINK ENTERPRISE | Doland | S320 Community Improvement & Capacity Building | $340k | 1 |
| WATERTOWN HOCKEY ASSOCIATION INC | Watertown | — | $340k | 0 |
| Western Hills Humane Society | Spearfish | — | $339k | 0 |
| FRATERNAL ORDER OF EAGLES | Vermillion | — | $339k | 0 |
| ASTORIA VOLUNTEER FIRE DEPARTMENT INC | Astoria | M24 Public Safety, Disaster Preparedness & Relief | $337k | 0 |
| NDN FUND INC | Rapid City | S12 Community Improvement & Capacity Building | $337k | 1 |
| Groundworks Connect | Sioux Falls | K19 Food, Agriculture & Nutrition | $337k | 0 |
| SOUTH DAKOTA MUNICIPAL LEAGUE GROUP | Ft Pierre | — | $337k | 0 |
| HAITI ALIVE INC | Tea | Q33 International, Foreign Affairs & National Security | $336k | 0 |
| DONALD STIP CHARITABLE REMAINDER | Sioux Falls | T90 Philanthropy, Voluntarism & Grantmaking Foundations | $336k | 1 |
| FRATERNAL ORDER OF EAGLES RAPID CITY 3555 | Rapid City | Y82 Mutual & Membership Benefit | $335k | 2 |
| SOUTH DAKOTA ASSOCIATION OF COOPERATIVES | Pierre | — | $333k | 1 |
| EYES UP SPORTS MINISTRIES | Sioux Falls | N11 Recreation & Sports | $333k | 4 |
| Alpha XI Delta Building Corporation | Yankton | — | $332k | 0 |
| BRANDON VALLEY CHAMBER OF COMMERCE | Brandon | — | $331k | 1 |
| MAIN STREET LIVING INC | Sioux Falls | X20 Religion-Related | $331k | 1 |
| DISABLED AMERICAN VETERANS | Sioux Falls | — | $331k | 2 |
| Westside Christian School Inc | Sioux Falls | B20 Education | $331k | 0 |
| SOUTH DAKOTA ASSN OF PLUMBING - | Sioux Falls | — | $330k | 1 |
| THE MIKE CINDY AND KYLIE HUETHER | Sioux Falls | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $329k | 0 |
| NAMI SOUTH DAKOTA | Sioux Falls | — | $328k | 1 |
| GROOVE INC | Sioux Falls | A6C Arts, Culture & Humanities | $328k | 3 |
| SOUTH DAKOTA SHERIFFS ASSOCIATION | Eureka | N03 Recreation & Sports | $328k | 0 |
| MCCOOK COUNTRY CLUB | Salem | — | $326k | 0 |
| CHILDREN'S CARE CORNER | Howard | P33 Human Services | $325k | 0 |
| SIOUX FALLS CARES INC | Sioux Falls | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $325k | 0 |
| HEALTHCARE LAUNDRY ACCREDITATION | Rapid City | S41 Community Improvement & Capacity Building | $324k | 1 |
| SOUTH DAKOTA CHAPTER INC - ACPA | Sioux Falls | T11 Philanthropy, Voluntarism & Grantmaking Foundations | $323k | 0 |
| VERMILLION RURAL FIRE DEPARTMENT | Vermillion | M24 Public Safety, Disaster Preparedness & Relief | $323k | 0 |
| Aliive Roberts County Inc | Sisseton | I21 Crime & Legal-Related | $323k | 3 |
| McIntosh Community Daycare | McIntosh | P33 Human Services | $322k | 0 |
| BURKE RIDING CLUB | Burke | — | $321k | 0 |
| DELTA GAMMA CHAPTER ASSOCIATION | Vermillion | — | $321k | 0 |
| BRANDON VALLEY BAND PARENTS INC | Brandon | B82 Education | $321k | 0 |
| VETERANS OF FOREIGN WARS | Madison | — | $320k | 1 |
| CHAMBER OF COMMERCE | Hot Springs | — | $320k | 0 |
