| THE COVERING HOUSE | Saint Louis | P62 Human Services | $5.2M | 1 |
| St Vincent's Medical Center | St Louis | E220 Health Care | $5.2M | 3 |
| CHILDRENS SMILE CENTER CSC | Ozark | E32 Health Care | $5.2M | 1 |
| LOGOS INC | St Louis | B28 Education | $5.2M | 2 |
| GREENE COUNTY AGRICULTURAL AND MECHANICAL SOCIETY OF SPRINGFIELD | Springfield | — | $5.2M | 3 |
| FEED MY PEOPLE | Saint Louis | P600 Human Services | $5.2M | 2 |
| KATHRYN REDD SMITH CHARITABLE TRUST UAD 518 | St Louis | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $5.2M | 1 |
| NEWHOUSE INC | Kansas City | Z99Z Unknown | $5.2M | 1 |
| Sinquefield Center for Research Inc | St Louis | B11 Education | $5.1M | 2 |
| KROENKE FAMILY FOUNDATION | Columbia | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $5.1M | 0 |
| AAIM MANAGEMENT SERVICES | St Louis | S41 Community Improvement & Capacity Building | $5.1M | 9 |
| COMMUNITY PARTNERSHIP OF SOUTHEAST MISSOURI | Cape Girardeau | S50P Community Improvement & Capacity Building | $5.1M | 1 |
| OUR LADY OF LIFE APARTMENTS | St Louis | P750 Human Services | $5.1M | 3 |
| THOMAS JEFFERSON INDEP DAY SCHOOL | Joplin | B20Z Education | $5.1M | 1 |
| RISE COMMUNITY SERVICES | Warrensburg | P80 Human Services | $5.1M | 2 |
| ORTHOPEDIC FOUNDATION FOR ANIMALS | Columbia | — | $5.1M | 1 |
| JEFFERSON CITY COUNTRY CLUB | Jefferson City | — | $5.1M | 1 |
| FATHERS SUPPORT CENTER ST LOUIS | Saint Louis | P40 Human Services | $5.1M | 4 |
| COMMUNITY SERVICES INC OF NORTHWEST MISSOURI | Maryville | — | $5.1M | 1 |
| UNITED IN CRISIS INC | Odessa | M20 Public Safety, Disaster Preparedness & Relief | $5.1M | 2 |
| LUTHER MANOR ASSOCIATION | Hannibal | — | $5.1M | 0 |
| ST LOUIS SHEET METAL JOINT APPRENTICESHIP FUND | St Louis | — | $5.1M | 4 |
| ST AGNES FOUNDATION INC | St Louis | E110 Health Care | $5M | 5 |
| HOLY ROSARY CREDIT UNION | Kansas City | — | $5M | 2 |
| THE LITTLE BIT FOUNDATION | Maryland Heights | P20 Human Services | $5M | 4 |
| Area Ministers for Christ Inc | Saint Joseph | P200 Human Services | $5M | 0 |
| UNITED FOOD AND COMMERCIAL WORKERS 655 LOCAL | Ballwin | — | $5M | 20 |
| AcruxKC | Kansas City | E11 Health Care | $5M | 1 |
| CLOUD 9 RANCH CLUB INC | Caulfield | — | $5M | 0 |
| LEARNING OPPORTUNITIES QUALITY WORKS INC | Monroe City | J30Z Employment | $5M | 0 |
| MERCY HEALTH FOUNDATION SOUTH | St Louis | E112 Health Care | $5M | 7 |
| DOWNTOWN KANSAS CITY COMMUNITY IMPROVEMENT DISTRICT | Kansas City | — | $5M | 3 |
| GREATER KANSAS CITY LABORERS' WELFARE FUND | Kansas City | — | $4.9M | 0 |
| CLINTON CONVALESCENT CENTER INC | Plattsburg | E91Z Health Care | $4.9M | 2 |
| SHARE AND CARE FOR SPECIAL PEOPLE INC | Clinton | P82Z Human Services | $4.9M | 1 |
| VISITING NURSE ASSOCIATION OF GREATER ST LOUIS | St Louis | E92Z Health Care | $4.9M | 7 |
| SOUTHSIDE EARLY CHILDHOOD CENTER | St Louis | P33Z Human Services | $4.9M | 1 |
| MISSOURI CENTRAL CREDIT UNION | Lees Summit | — | $4.9M | 2 |
| HIGH HOPE EMPLOYMENT SERVICES INC | Milan | — | $4.9M | 1 |
| MIDLAND EMPIRE RESOURCES FOR INDEPENDENT LIVING INC (MERIL) | Saint Joseph | — | $4.9M | 2 |
| St Louis Police Foundation | St Louis | M11 Public Safety, Disaster Preparedness & Relief | $4.9M | 1 |
| THE CHILDREN'S PLACE INC | Kansas City | I720 Crime & Legal-Related | $4.9M | 3 |
| Refuge and Restoration | Florissant | P20 Human Services | $4.9M | 1 |
| MISSOURI LAWYER TRUST ACCOUNT FOUNDATION | Jefferson City | T70Z Philanthropy, Voluntarism & Grantmaking Foundations | $4.9M | 1 |
| VOLUNTARY ACTION CENTER | Columbia | T40Z Philanthropy, Voluntarism & Grantmaking Foundations | $4.9M | 1 |
| ST FRANCOIS COUNTY BOARD FOR THE DEVELOPMENTALLY DISABLED | Farmington | G20 Diseases, Disorders & Medical Disciplines | $4.9M | 1 |
| JMG FOUNDATION | St Louis | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $4.9M | 0 |
| MISSOURI BANKERS ASSOCIATION | Jefferson City | — | $4.9M | 8 |
| Catholic Charities of Central and Northern Missouri | Jefferson City | P99 Human Services | $4.9M | 2 |
| THE MOOG CENTER FOR DEAF EDUCATION | Saint Louis | B28Z Education | $4.8M | 2 |
