| CLEVELAND CENTER FOR ARTS AND TECHNOLOGY | Cleveland | A6E Arts, Culture & Humanities | $6.1M | 2 |
| EARLY CHILDHOOD RESOURCE CENTER | Cleveland | P20 Human Services | $6M | 3 |
| CISE | Cincinnati | X22 Religion-Related | $6M | 1 |
| DARKE COUNTY RECOVERY SERVICES INC | Greenville | F20Z Mental Health & Crisis Intervention | $6M | 5 |
| THE WESTERN HILLS COUNTRY CLUB CO | Cincinnati | — | $6M | 1 |
| HOCKING VALLEY MEDICAL GROUP INC | Logan | E20Z Health Care | $6M | 9 |
| XCS INC | Xenia | — | $6M | 1 |
| Beacon Charitable Pharmacy Inc | Canton | E60 Health Care | $6M | 2 |
| THE MARGARET CLARK MORGAN FOUNDATION | Hudson | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $6M | 10 |
| STEPPING STONES INC | Cincinnati | P800 Human Services | $6M | 3 |
| LIFE ENRICHING COMMUNITIES FOUNDATION | Loveland | P197 Human Services | $6M | 4 |
| Humility House | Austintown | — | $6M | 6 |
| JEWISH FEDERATION OF GREATER DAYTON INC | Dayton | T700 Philanthropy, Voluntarism & Grantmaking Foundations | $6M | 2 |
| JEFFERSON COUNTY COMMUNITY ACTION COUNCIL INC | Steubenville | P20Z Human Services | $6M | 4 |
| JACKSON COUNTY HEALTH FACILITY INC | Wellston | — | $6M | 2 |
| ST VINCENT CHARITY MEDICAL CENTER | Cleveland | P30 Human Services | $6M | 11 |
| Jackson County Water Company Inc | Jackson | — | $6M | 1 |
| FURNITURE BANK OF CENTRAL OHIO | Columbus | P80 Human Services | $6M | 1 |
| TAFT MUSEUM OF ART | Cincinnati | A51 Arts, Culture & Humanities | $6M | 3 |
| Phi Delta Theta Foundation | Oxford | — | $6M | 2 |
| Legal Defenders Office of Summit County Ohio Inc | Akron | I80 Crime & Legal-Related | $6M | 1 |
| Buckeye Online School for Success | E Liverpool | B20 Education | $6M | 8 |
| MOUNT AUBURN PREPARATORY ACADEMY | Cincinnati | B29 Education | $6M | 6 |
| ALTERNATIVE PATHS INC | Medina | F30Z Mental Health & Crisis Intervention | $6M | 0 |
| Devon Oaks Assisted Living Corporation | Westlake | L22 Housing & Shelter | $6M | 4 |
| BUILDING TRADES WELFARE FUND FOR THE OHIO VALLEY | Saint Clairsville | — | $6M | 0 |
| THE AUSTIN E KNOWLTON FOUNDATION INC | Cincinnati | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $5.9M | 4 |
| American Heritage Girls Inc | Cincinnati | O40 Youth Development | $5.9M | 4 |
| THE REINBERGER FOUNDATION | Cleveland | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $5.9M | 12 |
| FRIENDS AND FAMILY CREDIT UNION | Massillon | — | $5.9M | 2 |
| HOSPICE CARE OF MIDDLETOWN INC | Middletown | P74 Human Services | $5.9M | 1 |
| TOLEDO SCIENCE CENTER | Toledo | A570 Arts, Culture & Humanities | $5.9M | 1 |
| OHIO DISABILITY RIGHTS LAW & POLICY CENTER INC | Columbus | R23 Civil Rights, Social Action & Advocacy | $5.9M | 5 |
| UPWARD BOUND YOUTH | Wooster | X99 Religion-Related | $5.9M | 4 |
| MARGARET M AND ROBERT D WALTER FOUNDATION | Columbus | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $5.9M | 0 |
| Horizon Science Academy Springfield | Toledo | B29 Education | $5.9M | 1 |
| OHIO LOCAL NEWS INITIATIVE INC | Columbus | A30 Arts, Culture & Humanities | $5.9M | 4 |
| LIMA UMADAOP | Lima | F20Z Mental Health & Crisis Intervention | $5.9M | 1 |
| PAST FOUNDATION | Columbus | A70 Arts, Culture & Humanities | $5.9M | 0 |
| Columbus Preparatory and Fitness Academy | Columbus | B28 Education | $5.9M | 0 |
| THE ARIEL FOUNDATION | Mount Vernon | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $5.9M | 0 |
| SID PUBLIC SERVICES ASSOCIATION | Columbus | S990 Community Improvement & Capacity Building | $5.9M | 1 |
| UNITED ASSOCIATION OF JOURNEYMEN & APPRENTICES OF THE PLUMBING & PIPE | Cincinnati | — | $5.9M | 13 |
| FOCUS LEARNING ACADEMY SOUTHWEST | Columbus | B90 Education | $5.9M | 6 |
| Knox County Head Start Inc | Mount Vernon | B22Z Education | $5.8M | 1 |
| FLYING HORSE FARMS | Mt Gilead | N20 Recreation & Sports | $5.8M | 4 |
| ELIZABETH'S NEW LIFE CENTER INC | Dayton | P20 Human Services | $5.8M | 1 |
| FUGEES FAMILY INC | Columbus | N64 Recreation & Sports | $5.8M | 1 |
| TECHSOLVE INC | Cincinnati | S400 Community Improvement & Capacity Building | $5.8M | 7 |
| BRIDGEWAY THERAPY CENTER | Columbus | P20 Human Services | $5.8M | 2 |
