| ISRAEL GUIDE DOG CENTER FOR THE BLIND | Warrington | P110 Human Services | $4.1M | 1 |
| FAMILY SERVICE AND CHILDREN'S AID SOCIETY OF VENANGO COUNTY | Oil City | I72 Crime & Legal-Related | $4.1M | 1 |
| Entergy Corporation Companies' Non-Bargaining Employees' Welfare Benefit Trust | Pittsburgh | — | $4.1M | 1 |
| CENTRE LIFELINK EMERGENCY MEDICAL SERVICES INC | State College | E62Z Health Care | $4.1M | 1 |
| FOUNDATION FOR READING AREA COMMUNITY COLLEGE | Reading | B41I Education | $4.1M | 1 |
| JUNIOR ACHIEVEMENT OF WESTERN PENNSYLVANIA INC | Bridgeville | Q320 International, Foreign Affairs & National Security | $4.1M | 3 |
| JUDITH CREED HORIZONS FOR ACHIEVING INDEPENDENCE | Bryn Mawr | P73Z Human Services | $4.1M | 1 |
| The Lamb Foundation | North Wales | L24 Housing & Shelter | $4.1M | 0 |
| ABOLITIONIST LAW CENTER | Pittsburgh | I83 Crime & Legal-Related | $4.1M | 3 |
| MANCHESTER BIDWELL CORPORATION | Pittsburgh | W02 Public & Societal Benefit | $4.1M | 4 |
| WALKER TOWNSHIP WATER ASSOCIATION INC | Mingoville | — | $4.1M | 1 |
| CENTER SCHOOL | Abington | — | $4.1M | 1 |
| UNION SNYDER AGENCY ON AGING | Lewisburg | P99 Human Services | $4.1M | 1 |
| TWIN TREES INC | Connellsville | P730 Human Services | $4.1M | 0 |
| FEDERATION HOUSING INC | Philadelphia | S31 Community Improvement & Capacity Building | $4.1M | 1 |
| TWU LOCAL 234 AFL-CIO | Philadelphia | — | $4.1M | 15 |
| LIVING BRANCHES | Souderton | L22Z Housing & Shelter | $4.1M | 8 |
| THE SHEPHERD FAMILY CHARITABLE FOUNDATION | Souderton | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $4.1M | 0 |
| HEART OF TEXAS CHARITABLE TRUST | Pittsburgh | — | $4.1M | 1 |
| I C P A INC | Media | B99 Education | $4.1M | 4 |
| THREE RIVERS MOTHERS MILK BANK D/B/A MID-ATLANTIC MOTHERS' MILK BANK | Pittsburgh | Z99 Unknown | $4.1M | 1 |
| NONPROFIT DEVELOPMENT CORPORATION | Butler | S19 Community Improvement & Capacity Building | $4.1M | 0 |
| FAMILY CARE SERVICES INC | Chambersburg | P320 Human Services | $4.1M | 2 |
| NATURAL LANDS TRUST UDECL 123060 C/O BNY MELLON NA | Pittsburgh | C34 Environment | $4.1M | 1 |
| ST MARGARET FOUNDATION | Pittsburgh | E11 Health Care | $4.1M | 1 |
| THE WILMA THEATER | Philadelphia | A650 Arts, Culture & Humanities | $4.1M | 2 |
| UNITED UNION OF ROOFERS WATERPROOFERS A ALLIED WORKERS LOCAL NO 30 | Philadelphia | — | $4.1M | 7 |
| Philadelphia Bar Association | Philadelphia | — | $4.1M | 7 |
| Catholic Charities Counseling & Adoption Services of the Diocese of Erie Inc | Erie | — | $4.1M | 0 |
| Lawrence County Economic Development Corp | New Castle | — | $4.1M | 0 |
| BEECH INTERPLEX INC | Philadelphia | L250 Housing & Shelter | $4.1M | 3 |
| HACE | Philadelphia | S200 Community Improvement & Capacity Building | $4.1M | 2 |
| PHILADELPHIA INSURANCE COMPANIES FDN | Philadelphia | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $4.1M | 0 |
| THE DAVENPORT FAMILY FOUNDATION | Southeastern | I20Z Crime & Legal-Related | $4.1M | 3 |
| PITTSBURGH PENGUINS FOUNDATION | Pittsburgh | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $4.1M | 0 |
| TURNING POINT OF LEHIGH VALLEY INC | Allentown | P620 Human Services | $4.1M | 1 |
| CENTER FOR HEARING & DEAF SERVICES INC | Pittsburgh | — | $4M | 3 |
| AO NORTH AMERICA CHARITABLE FUND | Wayne | H50 Medical Research | $4M | 10 |
| NEW DAY CHARTER SCHOOL | Huntingdon | B90 Education | $4M | 0 |
| CENTRAL PENNSYLVANIA DIGITAL LEARNING FOUNDATION | Altoona | B29 Education | $4M | 0 |
| LIFE SCIENCES PENNSYLVANIA | King Of Prussia | — | $4M | 5 |
| COMMUNITY THERAPY BARN | Gordonville | P82 Human Services | $4M | 0 |
| United Association of Journeymen 520 PPF | Harrisburg | — | $4M | 10 |
| NON-PROFIT HOUSING DEVELOPMENT CORPORATION OF LEBANON COUNTY INC | Cleona | L20 Housing & Shelter | $4M | 1 |
| THREE RIVERS YOUTH | Pittsburgh | P300 Human Services | $4M | 2 |
| CARBON MONROE PIKE DRUG AND ALCOHOL COMMISSION INC | Stroudsburg | F20Z Mental Health & Crisis Intervention | $4M | 2 |
| THE PHILADELPHIA CULTURAL FUND INC | Philadelphia | A120 Arts, Culture & Humanities | $4M | 1 |
| AUTO DEALERS ASSOCIATION OF GREATER PHILADELPHIA | Norristown | — | $4M | 5 |
| CRAWFORD COUNTY DRUG & ALCOHOL EXECUTIVE COMMISSION INC | Meadville | F20Z Mental Health & Crisis Intervention | $4M | 1 |
| Phase 4 Learning Center Inc | Pittsburgh | B90 Education | $4M | 1 |
