| Healthfirst PHSP Inc | New York | E310 Health Care | $12.1B | 13 |
| New York University | New York | B430 Education | $11.6B | 24 |
| The New York and Presbyterian Hospital | New York | E220 Health Care | $10.3B | 38 |
| NYU LANGONE HOSPITALS | New York | E20G Health Care | $9.5B | 21 |
| MEMORIAL SLOAN-KETTERING CANCER CENTER | New York | E240 Health Care | $8.5B | 31 |
| THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | New York | B430 Education | $7.3B | 24 |
| Healthfirst Health Plan Inc | New York | — | $7B | 12 |
| GS DONOR ADVISED PHILANTHROPY FUND FOR WEALTH MANAGEMENT INC | New York | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $6.6B | 0 |
| Cornell University | Ithaca | B430 Education | $6.6B | 22 |
| UNIVERSITY OF ROCHESTER | Rochester | B430 Education | $5.9B | 35 |
| MONTEFIORE MEDICAL CENTER | Bronx | E220 Health Care | $5.9B | 9 |
| HEALTH INSURANCE PLAN OF GREATER NEW YORK | New York | E320 Health Care | $5.3B | 28 |
| METROPLUS HEALTH PLAN INC | New York | E31 Health Care | $5.2B | 17 |
| THE MOUNT SINAI HOSPITAL | New York | E22 Health Care | $4.7B | 20 |
| ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI | New York | B500 Education | $4.5B | 23 |
| LONG ISLAND JEWISH MEDICAL CENTER C/O NORTHWELL HEALTH INC | Westbury | E20 Health Care | $4.1B | 20 |
| NORTH SHORE UNIVERSITY HOSPITAL | Westbury | E20 Health Care | $3.9B | 18 |
| ALBANY MEDICAL CENTER GROUP ORGANIZATION | Albany | — | $3.3B | 62 |
| MVP HEALTH PLAN INC | Schenectady | — | $3.2B | 25 |
| The Boeing Company Veba Master Trust | Brooklyn | Y43 Mutual & Membership Benefit | $2.8B | 1 |
| NORTHWELL HEALTHCARE INC | Westbury | E32 Health Care | $2.7B | 18 |
| VNS CHOICE | New York | E920 Health Care | $2.5B | 8 |
| 1199SEIU NATIONAL BENEFIT FUND FOR HEALTH AND HUMAN SERVICE EMPLOYEES | New York | Y43 Mutual & Membership Benefit | $2.2B | 9 |
| Lenox Hill Hospital C/O NORTHWELL HEALTH INC | Westbury | E22 Health Care | $2.2B | 18 |
| PFIZER PATIENT ASSISTANCE FOUNDATION INC | New York | E12 Health Care | $2.1B | 0 |
| CAPITAL DISTRICT PHYSICIANS' HEALTH PLAN INC | Latham | — | $2B | 37 |
| KALEIDA HEALTH | Buffalo | E220 Health Care | $1.9B | 20 |
| SYRACUSE UNIVERSITY | Syracuse | B430 Education | $1.9B | 21 |
| The Research Foundation for The State University of New York | Albany | B114 Education | $1.9B | 13 |
| BUILDING SERVICE 32BJ HEALTH FUND | New York | J40 Employment | $1.8B | 20 |
| Village Senior Services Corporation | New York | E800 Health Care | $1.7B | 11 |
| THE ROCHESTER GENERAL HOSPITAL | Rochester | E220 Health Care | $1.7B | 20 |
| INDEPENDENT HEALTH ASSOCIATION INC | Buffalo | E99 Health Care | $1.7B | 45 |
| NEW YORK SOCIETY FOR THE RELIEF OF THE RUPTURED AND CRIPPLED MAINTAINING THE | New York | E240 Health Care | $1.7B | 24 |
| MEMORIAL SLOAN-KETTERING CANCER CENTER | New York | E120 Health Care | $1.7B | 23 |
| STATEN ISLAND UNIVERSITY HOSPITAL | Westbury | E220 Health Care | $1.6B | 18 |
| THE BLOOMBERG FAMILY FOUNDATION INC | New York | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $1.6B | 22 |
| Conference on Jewish Material Claims Against Germany Inc | New York | — | $1.6B | 8 |
| ST LUKE'S-ROOSEVELT HOSPITAL CENTER | New York | E22 Health Care | $1.6B | 19 |
| Maimonides Medical Center | Brooklyn | E220 Health Care | $1.6B | 14 |
| ELDERPLAN INC | New York | E310 Health Care | $1.6B | 11 |
| INTERNATIONAL RESCUE COMMITTEE INC | New York | Q710 International, Foreign Affairs & National Security | $1.5B | 12 |
| CITY UNIVERSITY CONSTRUCTION FUND | New York | B110 Education | $1.3B | 8 |
| SOUTH SHORE UNIVERSITY HOSPITAL C/O NORTHWELL HEALTH INC | Westbury | E20 Health Care | $1.2B | 18 |
| College Board | New York | B900 Education | $1.2B | 17 |
| UNITED HEALTH SERVICES HOSPITALS INC | Binghamton | E220 Health Care | $1.2B | 22 |
| Rochester Institute of Technology | Rochester | B430 Education | $1.2B | 23 |
| THE FORD FOUNDATION | New York | T21 Philanthropy, Voluntarism & Grantmaking Foundations | $1.1B | 22 |
| JEWISH COMMUNAL FUND | New York | T700 Philanthropy, Voluntarism & Grantmaking Foundations | $1.1B | 11 |
| Elderserve Health Inc | Bronx | E920 Health Care | $1.1B | 11 |
