| CHILDREN'S MUSEUM OF SOUTH DAKOTA | Brookings | T23 Philanthropy, Voluntarism & Grantmaking Foundations | $2.2M | 1 |
| THE BANQUET | Sioux Falls | K35 Food, Agriculture & Nutrition | $2.2M | 0 |
| COLLISION MINISTRIES INC | Sioux Falls | O50 Youth Development | $2.2M | 0 |
| OYATE TECA PROJECT INC | Kyle | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $2.2M | 1 |
| JOHN D & EDNA HOFER TRUST | Mitchell | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $2.2M | 1 |
| BOYS AND GIRLS CLUB OF THE CAPITAL AREA | Pierre | O23 Youth Development | $2.2M | 1 |
| INTERNATIONAL BROTHERHOOD OF LOCAL 426 | Sioux Falls | — | $2.2M | 8 |
| SOUTH DAKOTA PARKS AND WILDLIFE FOUNDATION | Pierre | — | $2.1M | 1 |
| SOUTH DAKOTA BLACK HILLS BADLANDS AND LAKES ASSOCIATION INC | Rapid City | — | $2.1M | 1 |
| MISSION HAITI | Sioux Falls | X99 Religion-Related | $2.1M | 2 |
| James Valley Christian School | Huron | — | $2.1M | 3 |
| WORKING AGAINST VIOLENCE INC | Rapid City | — | $2.1M | 2 |
| MAZASKA OWECASO OTIPI FINANCIAL INC | Pine Ridge | L82 Housing & Shelter | $2.1M | 5 |
| ADDICTION RECOVERY CENTERS OF THE BLACK HILLS | Rapid City | F22Z Mental Health & Crisis Intervention | $2.1M | 1 |
| WESTERN DAKOTA VOCATIONAL TECHNICAL FOUNDATION INC | Rapid City | — | $2.1M | 1 |
| EARLY CHILDHOOD CONNECTIONS | Rapid City | A20 Arts, Culture & Humanities | $2M | 1 |
| SOUTH DAKOTA STATE FAIR FOUNDATION | Huron | S99Z Community Improvement & Capacity Building | $2M | 0 |
| LIVE BRAVE FOUNDATION | Harrisburg | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $2M | 0 |
| PONTIUS FAMILY FOUNDATION 007151 | Sioux Falls | T22Z Philanthropy, Voluntarism & Grantmaking Foundations | $2M | 1 |
| East River Legal Services Corporation | Sioux Falls | I83Z Crime & Legal-Related | $2M | 1 |
| Clark Rural Water System Inc | Clark | — | $2M | 10 |
| Makoce Agriculture Development | Porcupine | K20 Food, Agriculture & Nutrition | $2M | 2 |
| WESTERN DAKOTA REGIONAL WATER SYSTEM | Rapid City | W80 Public & Societal Benefit | $2M | 1 |
| ECDYSIS FOUNDATION | Estelline | H99 Medical Research | $2M | 1 |
| SOUTH DAKOTA STATE MEDICAL ASSOCIATION | Sioux Falls | — | $1.9M | 3 |
| FOUNDATION FOR CHRISTIAN DISCIPLES | Spearfish | — | $1.9M | 3 |
| SOCIETY OF ST VINCENT DE PAUL OF SIOUX FALLS | Sioux Falls | — | $1.9M | 0 |
| TECHNOLOGY FOR RURAL ENHANCEMENT OF COMMUNITIES | Belle Fourche | S20Z Community Improvement & Capacity Building | $1.9M | 2 |
| THE BLACK HILLS PLAYHOUSE INC | Rapid City | A650 Arts, Culture & Humanities | $1.9M | 0 |
| ABERDEEN CHRISTIAN SCHOOL INC | Aberdeen | B24Z Education | $1.9M | 1 |
| GREAT BEAR MANAGEMENT INC | Sioux Falls | — | $1.9M | 1 |
| BOYS & GIRLS CLUB OF ABERDEEN AREA INC | Aberdeen | — | $1.8M | 0 |
| Three Rivers Mental Health & Chemical Dependency Center | Lemmon | F32Z Mental Health & Crisis Intervention | $1.8M | 0 |
| NORTHEAST SD HEALTH CARE FOUNDATION % DARYL HALVORSON | Milbank | S202 Community Improvement & Capacity Building | $1.8M | 0 |
| MOUNTAIN PLAINS COMMUNITY DEVELOPMENT | Sioux Falls | S30 Community Improvement & Capacity Building | $1.8M | 0 |
| DAVISON RURAL WATER SYSTEM | Mitchell | — | $1.8M | 7 |
| MAMMOTH SITE OF HOT SPRINGS SOUTH DAKOTA INC | Hot Springs | A560 Arts, Culture & Humanities | $1.8M | 0 |
| OAHE FOUNDATION | Pierre | T310 Philanthropy, Voluntarism & Grantmaking Foundations | $1.8M | 0 |
| Heartland Health Resource Center | Sioux Falls | E60 Health Care | $1.8M | 1 |
| Dakota Business Finance | Sioux Falls | S990 Community Improvement & Capacity Building | $1.8M | 0 |
| SPEARFISH EMERGENCY AMBULANCE SERVICE | Spearfish | E62Z Health Care | $1.8M | 1 |
| Glacier Care Center Inc | Spearfish | E91 Health Care | $1.8M | 1 |
| MITCHELL TECHNICAL COLLEGE FOUNDATION | Mitchell | B82 Education | $1.8M | 0 |
| SICANGU COMMUNITY DEVELOPMENT CORPORATION | Mission | S40 Community Improvement & Capacity Building | $1.8M | 0 |
| DISABILITY RIGHTS SOUTH DAKOTA | Pierre | — | $1.8M | 2 |
| WOLAKOTA WALDORF SOCIETY | Kyle | — | $1.8M | 2 |
| Brookings Country Club | Brookings | — | $1.8M | 0 |
| SOUTH DAKOTA BANKERS ASSOCIATION | Pierre | — | $1.7M | 2 |
| KINGDOM CAPITAL FUND | Sioux Falls | X21 Religion-Related | $1.7M | 2 |
| SIOUX COUNCIL BOY SCOUTS OF AMERICA INC | Sioux Falls | — | $1.7M | 0 |
