| PONDEROSA APARTMENTS INC | Spearfish | L21 Housing & Shelter | $3M | 0 |
| COMPASSION CHILD CARE | Sioux Falls | P3 Human Services | $3M | 0 |
| DAKOTA PLAINS LEGAL SERVICES | Mission | — | $3M | 3 |
| MENNO-OLIVET CARE CENTER INC | Menno | P750 Human Services | $3M | 1 |
| VERMILLION AREA CHAMBER OF COMMERCE AND DEVELOPMENT COMPANY | Vermillion | — | $3M | 0 |
| VIA-BRADLEY COLLEGE OF ENGINEERING FOUND C/O FIRST PREMIER BANK TRUST DEPARTMENT | Sioux Falls | B120 Education | $3M | 0 |
| WAKONDA HERITAGE MANOR | Wakonda | P750 Human Services | $3M | 1 |
| BLACK HILLS WORKS FOUNDATION INC | Rapid City | J00I Employment | $3M | 0 |
| BLACK HILLS AREA HABITAT FOR HUMANITY | Rapid City | L20Z Housing & Shelter | $2.9M | 2 |
| SOUTH DAKOTA NETWORK AGAINST FAMILY VIOLENCE AND SEXUAL ASSAULT INC | Sioux Falls | — | $2.9M | 1 |
| ST FRANCIS HOUSE OF SIOUX FALLS | Sioux Falls | — | $2.8M | 1 |
| DELTA DENTAL OF SOUTH DAKOTA FOUNDATION | Pierre | E34K Health Care | $2.8M | 2 |
| Strand-Kjorsvig Community Rest Home | Roslyn | E91Z Health Care | $2.8M | 0 |
| RED CLOUD RENEWABLE | Pine Ridge | C35 Environment | $2.8M | 4 |
| Denny Sanford Foundation C/O First PREMIER Bank | Sioux Falls | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $2.8M | 0 |
| MITCHELL AREA SAFEHOUSE INC | Mitchell | P43Z Human Services | $2.8M | 0 |
| LIVE CENTER INC | Lemmon | — | $2.8M | 2 |
| SACRED HEART CENTER | Eagle Butte | P43Z Human Services | $2.8M | 1 |
| HOUSTON FAMILY FOUNDATION | Sioux Falls | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $2.7M | 6 |
| MCCROSSAN FOUNDATION INC | Sioux Falls | — | $2.7M | 0 |
| BOB AND EILEEN GILMAN FAMILY FOUNDATION | Sioux Falls | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $2.7M | 0 |
| TRE MINISTRIES | Sioux Falls | X20 Religion-Related | $2.7M | 1 |
| SIOUX EMPIRE FAIR ASSOCIATION INC | Sioux Falls | N52 Recreation & Sports | $2.7M | 1 |
| H & M KELLOGG CHARITABLE TRUST | Sioux Falls | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $2.7M | 3 |
| LUTHERAN SOCIAL SERVICES OF SD FOUNDATION | Sioux Falls | — | $2.7M | 2 |
| MAKE-A-WISH FOUNDATION OF SOUTH DAKOTA & MONTANA | Sioux Falls | — | $2.6M | 2 |
| SOUTHERN PLAINS BEHAVIORAL HEALTH SERVICES | Winner | — | $2.6M | 2 |
| AMERICAN COALITION FOR ETHANOL | Sioux Falls | — | $2.6M | 2 |
| ONEHEART | Rapid City | L41 Housing & Shelter | $2.5M | 2 |
| SICANGU OWAYAWA OTI | Mission | B90 Education | $2.5M | 9 |
| Monument Health Inc | Rapid City | E21 Health Care | $2.5M | 7 |
| THE JAMES AND ELOISE ELMEN FOUNDATION | Sioux Falls | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $2.5M | 1 |
| ACTION FOR BETTERMENT OF COMMUNITY | Sturgis | I21 Crime & Legal-Related | $2.5M | 2 |
| ASSOCIATED SCHOOL BOARDS OF SOUTH DAKOTA INC | Pierre | — | $2.5M | 19 |
| Area IV Senior Citizens Planning Council Inc | Aberdeen | P810 Human Services | $2.4M | 2 |
| St Francis Mission | St Francis | X220 Religion-Related | $2.4M | 2 |
| ABBOTT HOUSE FOUNDATION INC | Mitchell | P34J Human Services | $2.4M | 0 |
| SPECIAL OLYMPICS SOUTH DAKOTA INC | Sioux Falls | N72Z Recreation & Sports | $2.4M | 0 |
| SOUTH DAKOTA HISTORICAL SOCIETY FOUNDATION | Pierre | A80 Arts, Culture & Humanities | $2.4M | 1 |
| MOCCASIN CREEK COUNTRY CLUB | Aberdeen | — | $2.3M | 0 |
| UNITED WAY OF THE BLACK HILLS | Rapid City | T00J Philanthropy, Voluntarism & Grantmaking Foundations | $2.3M | 2 |
| FREEMAN ACADEMY & FREEMAN JUNIOR COLLEGE | Freeman | B200 Education | $2.3M | 1 |
| RURAL ELECTRIC ECONOMIC DEVELOPMENT INC | Madison | S32 Community Improvement & Capacity Building | $2.3M | 0 |
| Dakota Alliance Soccer Club | Sioux Falls | N64Z Recreation & Sports | $2.3M | 0 |
| Sunshine Bible Academy | Miller | B24Z Education | $2.3M | 1 |
| Black Hills Center for American Indian Health | Rapid City | E052 Health Care | $2.2M | 2 |
| INSTITUTE OF THE RANGE & THE AMERICAN MUSTANG | Hot Springs | D340 Animal-Related | $2.2M | 1 |
| SOUTH DAKOTA RETAILERS ASSOCIATION | Pierre | — | $2.2M | 1 |
| MARGARET CHRISTOPHERSON CHARITABLE TR | Sioux Falls | D20 Animal-Related | $2.2M | 1 |
| ATM INDUSTRY ASSOCIATION | Sioux Falls | S41 Community Improvement & Capacity Building | $2.2M | 6 |
