| Dixon Gallery and Gardens | Memphis | A510 Arts, Culture & Humanities | $6.1M | 2 |
| URBAN LEAGUE OF GREATER CHATTANOOGA | Chattanooga | S20Z Community Improvement & Capacity Building | $6.1M | 1 |
| YOUTH TOWN OF TENNESSEE INC | Jackson | P320 Human Services | $6.1M | 1 |
| TENNESSEE CHAPTER OF CHILDREN'S ADVOCACY | Nashville | P013 Human Services | $6.1M | 1 |
| AMERICAN BAPTIST THEOLOGICAL SEMINARY | Nashville | B42Z Education | $6M | 5 |
| Memphis Center For Reproductive Health Inc | Memphis | — | $6M | 6 |
| CENTERSTONE RESEARCH INSTITUTE INC | Nashville | F050 Mental Health & Crisis Intervention | $6M | 7 |
| TAMB OF JACKSON TENNESSEE INC | Jackson | — | $6M | 0 |
| BOYS AND GIRLS CLUBS OF MIDDLE | Nashville | O23Z Youth Development | $6M | 1 |
| THE CONSTRUCTION SPECIFICATIONS | Brentwood | — | $6M | 5 |
| Montessori Academy Incorporated | Brentwood | B21Z Education | $6M | 0 |
| BOYS & GIRLS CLUBS OF THE OCOEE | Cleveland | — | $5.9M | 1 |
| KNOX EDUCATION FOUNDATION | Knoxville | B12 Education | $5.9M | 1 |
| ASSOCIATION OF INFANT MENTAL | Nashville | F80 Mental Health & Crisis Intervention | $5.9M | 1 |
| MILTON AND DENICE JOHNSON FAMILY | Nashville | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $5.9M | 0 |
| MARY QUEEN OF ANGELS INC | Nashville | — | $5.9M | 4 |
| PROJECT K9 HERO | Whitwell | D12 Animal-Related | $5.9M | 1 |
| FRIENDS OF THE WARNER PARKS INC | Nashville | N32I Recreation & Sports | $5.9M | 2 |
| FRIENDS OF GREAT SMOKY MOUNTAINS | Kodak | N32 Recreation & Sports | $5.9M | 2 |
| ASSOCIATION FOR GUIDANCE AID | Nashville | P46Z Human Services | $5.9M | 1 |
| LANE MOTOR MUSEUM | Nashville | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $5.9M | 1 |
| PARTNERSHIP FOR FAMILIES CHILDREN | Chattanooga | S50Z Community Improvement & Capacity Building | $5.9M | 2 |
| CROWN FINANCIAL MINISTRIES INC | Knoxville | X20Z Religion-Related | $5.8M | 8 |
| BELIEVE MEMPHIS ACADEMY INC | Memphis | B29 Education | $5.8M | 3 |
| Dyersburg-Dyer County Union Mission | Dyersburg | P200 Human Services | $5.8M | 1 |
| NEW HORIZONS COPORATION | Nashville | — | $5.8M | 2 |
| HOPE WORKS INC | Memphis | J20 Employment | $5.8M | 1 |
| Appalachian Conservation Institute Inc | Chattanooga | C30 Environment | $5.8M | 0 |
| FAITH FAMILY MEDICAL CENTER INC | Nashville | E32 Health Care | $5.8M | 5 |
| ENBRIGHT CREDIT UNION | Nashville | — | $5.8M | 1 |
| WOODLAND PRESBYTERIAN SCHOOL INC | Memphis | B24 Education | $5.7M | 2 |
| TNACHIEVES | Knoxville | B82 Education | $5.7M | 3 |
| GIRL SCOUT COUNCIL OF THE SOUTHERN | Knoxville | O42 Youth Development | $5.7M | 4 |
| TRI-COUNTY CENTER | Athens | — | $5.7M | 1 |
| CHATTANOOGA CHAMBER FOUNDATION | Chattanooga | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $5.7M | 4 |
| AMERICAN ASSOCIATION FOR LABORATORY | Memphis | D034 Animal-Related | $5.7M | 6 |
| MEMPHIS SYMPHONY ORCHESTRA INC | Memphis | A690 Arts, Culture & Humanities | $5.7M | 3 |
| NASHVILLE POLICE & PUBLIC SAFETY | Nashville | M11 Public Safety, Disaster Preparedness & Relief | $5.7M | 1 |
| Golden Gate Development Corporation | Memphis | P20 Human Services | $5.7M | 3 |
| DIAMOND G EMPLOYEE BENEFIT TRUST | Greeneville | — | $5.7M | 1 |
| TENNESSEE CHARITABLE CARE NETWORK | Franklin | E02 Health Care | $5.6M | 0 |
| TENNESSEE WALKING HORSE NATIONAL | Shelbyville | — | $5.6M | 1 |
| MEMPHIS MERIT ACADEMY INC | Memphis | B29 Education | $5.6M | 2 |
| Carter County Emergency Rescue Squad | Elizabethton | E62Z Health Care | $5.6M | 2 |
| HELEN ROSS MCNABB FOUNDATION | Knoxville | F30J Mental Health & Crisis Intervention | $5.6M | 2 |
| Fleetwood Foundation Inc | Memphis | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $5.6M | 1 |
| TENNESSEE WILDLIFE FEDERATION INC | Nashville | C013 Environment | $5.5M | 5 |
| STRIVE COLLEGIATE ACADEMY INC | Nashville | B99 Education | $5.5M | 1 |
| MEMORIAL HEALTH CARE SYSTEM FOUNDATION | Chattanooga | — | $5.5M | 10 |
| Vision Preparatory Charter School | Memphis | B99 Education | $5.5M | 0 |
