| INSTITUTE FOR ACADEMIC EXCELLENCE INC | New Orleans | B29 Education | $8.1M | 2 |
| SOUTHWEST LOUISIANA PRIMARY HEALTH CARE CENTER INC | Opelousas | E30Z Health Care | $8M | 8 |
| OUR LADY OF THE LAKE FOUNDATION | Baton Rouge | E12 Health Care | $8M | 8 |
| Foundation for Excellence in Louisiana Public Broadcasting | Baton Rouge | A110 Arts, Culture & Humanities | $7.9M | 1 |
| RESILIENCE FORCE | New Orleans | M20 Public Safety, Disaster Preparedness & Relief | $7.9M | 6 |
| THE CONTINENTAL FOUNDATION | Shreveport | — | $7.8M | 1 |
| SOUTHERN YACHT CLUB OF NEW ORLEANS | New Orleans | — | $7.8M | 2 |
| LAUREATE ACADEMY INC | Harvey | B29 Education | $7.7M | 1 |
| LOUISIANA QUARTER HORSE BREEDERS | Alexandria | — | $7.7M | 0 |
| Beloved Community Inc | New Orleans | S30 Community Improvement & Capacity Building | $7.6M | 1 |
| EDUCATION EXPLOSION INC | Baker | B90 Education | $7.5M | 2 |
| CROSSROADS LOUISIANA INC | New Orleans | L200 Housing & Shelter | $7.5M | 2 |
| SAMARITAN FUND NP INC | Metairie | G01 Diseases, Disorders & Medical Disciplines | $7.5M | 1 |
| FRIENDS OF WWOZ INC | New Orleans | A340 Arts, Culture & Humanities | $7.4M | 4 |
| OUACHITA CHRISTIAN SCHOOLS INC | Monroe | B24Z Education | $7.4M | 5 |
| Gayle and Tom Benson Charitable Foundation | Metairie | T99 Philanthropy, Voluntarism & Grantmaking Foundations | $7.4M | 0 |
| THE RAPIDES FOUNDATION | Alexandria | E210 Health Care | $7.3M | 5 |
| NEW ORLEANS HABITAT FOR HUMANITY | New Orleans | — | $7.3M | 5 |
| LOUISIANA HOSPITAL ASSOCIATION | Baton Rouge | — | $7.3M | 9 |
| CENLA AREA AGENCY ON AGING INC | Alexandria | P75Z Human Services | $7.3M | 1 |
| The Bridge Center for Hope | Baton Rouge | F20 Mental Health & Crisis Intervention | $7.2M | 1 |
| GREAT HEARTS LOUISIANA INC | Baton Rouge | B29 Education | $7.2M | 2 |
| CATHOLIC CHARITIES OF SOUTHWEST | Lake Charles | P20 Human Services | $7.2M | 0 |
| LAFON NURSING FACILITY OF THE HOLY | New Orleans | E91Z Health Care | $7.2M | 0 |
| CREST INDUSTRIES EMPLOYEE BENEFITS TRUST | Alexandria | — | $7.2M | 0 |
| ECOLE BILINGUE DE LA NOUVELLE ORLEANS | New Orleans | B21 Education | $7.2M | 2 |
| LIFE COAST COMMUNITY HEALTH CENTER INC | Thibodaux | — | $7.1M | 3 |
| YMCA of Northwest Louisiana | Shreveport | P27Z Human Services | $7.1M | 1 |
| BISHOP NOLAND EPISCOPAL DAY SCHOOL | Lake Charles | B20 Education | $7.1M | 0 |
| THE WOOLWORTH FOUNDATION | Shreveport | T900 Philanthropy, Voluntarism & Grantmaking Foundations | $7.1M | 0 |
| STUART HALL | New Orleans | — | $7.1M | 4 |
| NATIONAL PERFORMANCE NETWORK INC | New Orleans | A026 Arts, Culture & Humanities | $7M | 1 |
| Krewe of Bacchus Inc | New Orleans | — | $7M | 0 |
| SOUTHFIELD SCHOOL | Shreveport | B25Z Education | $7M | 1 |
| NORTHSHORE CHARTER SCHOOL | Bogalusa | B29 Education | $7M | 1 |
| EYE EAR NOSE & THROAT FOUNDATION | New Orleans | E110 Health Care | $6.9M | 2 |
| CAPITAL AREA AGENCY ON AGING INC | Baton Rouge | P81Z Human Services | $6.9M | 2 |
| JEFFERSON COUNCIL ON AGING INC | Metairie | P81Z Human Services | $6.9M | 1 |
| OAKBOURNE COUNTRY CLUB INC | Lafayette | — | $6.9M | 0 |
| FOUNDATION FOR WOMANS | Baton Rouge | E11 Health Care | $6.9M | 2 |
| Krewe of Cleopatra Inc | Covington | R19 Civil Rights, Social Action & Advocacy | $6.9M | 2 |
| CARC INC | Lake Charles | P80 Human Services | $6.9M | 2 |
| BATON ROUGE SPEECH AND HEARING | Baton Rouge | E56Z Health Care | $6.9M | 2 |
| MARY BIRD PERKINS CANCER | Baton Rouge | E11 Health Care | $6.9M | 5 |
| COVENANT HOUSE NEW ORLEANS | New Orleans | P30 Human Services | $6.8M | 3 |
| Ascension Credit Union | Gonzales | — | $6.8M | 0 |
| Plumbers and Steamfitters Local 141 Health and Welfare Fund | Shreveport | — | $6.8M | 0 |
| VOICES FOR INTERNATIONAL BUSINESS AND | New Orleans | B90 Education | $6.8M | 1 |
| BRENT HOUSE CORPORATION | New Orleans | Z99Z Unknown | $6.7M | 4 |
| NEW ORLEANS COUNCIL ON AGING INC | New Orleans | — | $6.7M | 1 |