| ASCENSION DEPAUL SERVICES | New Orleans | — | $10.2M | 7 |
| ST MARTIN IBERIA LAFAYETTE PARISH | Lafayette | S200 Community Improvement & Capacity Building | $10.2M | 1 |
| CITY OF FAITH PRISON MINISTRIES INC | Monroe | X21Z Religion-Related | $10.1M | 0 |
| THE DIOCESE OF BATON ROUGE CHILD | Baton Rouge | — | $10.1M | 1 |
| STARC OF LOUISIANA INC | Slidell | — | $10M | 3 |
| Elan Academy Inc dba Elan Academy Char | New Orleans | B29 Education | $10M | 2 |
| Southwest Louisiana AIDS Council | Lake Charles | G81Z Diseases, Disorders & Medical Disciplines | $9.9M | 1 |
| SOUTHWEST LOUISIANA AREA HEALTH | Lafayette | E39I Health Care | $9.9M | 0 |
| OPTIONS INC | Hammond | P820 Human Services | $9.9M | 1 |
| PLUMBERS & STEAMFITTERS LOCAL 60 HEALTH | Metairie | — | $9.8M | 1 |
| Louisiana Corp Credit Union | Metairie | — | $9.8M | 3 |
| LOUISIANA LIFE AND HEALTH INSURANCE | Baton Rouge | — | $9.8M | 0 |
| Prescott Area Childrens Education | Baton Rouge | B28 Education | $9.8M | 1 |
| Prairie Manor Inc | Pine Prairie | — | $9.7M | 2 |
| Encore Learning | New Orleans | — | $9.6M | 1 |
| THE YOUNG MEN'S CHRISTIAN ASSOCIATION | Baton Rouge | P270 Human Services | $9.6M | 5 |
| Taproot Earth | Slidell | C01 Environment | $9.6M | 7 |
| BRIDGE HOUSE CORPORATION | New Orleans | F34Z Mental Health & Crisis Intervention | $9.4M | 2 |
| JEWISH ENDOWMENT FOUNDATION | Metairie | T70Z Philanthropy, Voluntarism & Grantmaking Foundations | $9.3M | 2 |
| SOUTHERN UNITED STATES TRADE ASSOCIATION | New Orleans | — | $9.3M | 3 |
| ADVOCATES FOR SCIENCE & MATHEMATICS | New Orleans | B99Z Education | $9.3M | 0 |
| COUNCIL FOR ADVANCEMENT OF SOCIAL | Shreveport | I21 Crime & Legal-Related | $9.2M | 2 |
| VOICE OF THE EXPERIENCED VOTE | New Orleans | I40 Crime & Legal-Related | $9.1M | 2 |
| The Arc of Greater New Orleans | Metairie | — | $9.1M | 1 |
| LOUISIANA ASSOCIATION FOR THE BLIND INC | Shreveport | — | $9.1M | 5 |
| COMMUNITY COFFEE COMPANY LLC EMPLOYEE | Baton Rouge | — | $9M | 0 |
| INTERNATIONAL DOMINICAN FOUNDATION | Metairie | X22 Religion-Related | $9M | 0 |
| GOODWILL INDUSTRIES OF | Lafayette | J32Z Employment | $9M | 1 |
| THE LOUISIANA PHILHARMONIC ORCHESTRA | New Orleans | A69Z Arts, Culture & Humanities | $8.9M | 12 |
| AVOYELLES PUBLIC CHARTER SCHOOLINC | Mansura | B24 Education | $8.8M | 0 |
| NSU FOUNDATION INC | Natchitoches | B43I Education | $8.8M | 0 |
| SUCCESS PREPARATORY ACADEMY | New Orleans | B21 Education | $8.8M | 2 |
| BATON ROUGE CLINIC (A MEDICAL | Baton Rouge | — | $8.7M | 1 |
| DELTA COMMUNITY ACTION ASSOCIATION | Tallulah | S200 Community Improvement & Capacity Building | $8.6M | 1 |
| THE WELLSPRING ALLIANCE FOR FAMILIES INC | Monroe | P27Z Human Services | $8.6M | 1 |
| STEPHENSON STELLAR CORPORATION | Shrevport | U40 Science & Technology | $8.6M | 9 |
| LOUISIANA ASSET MANAGEMENT POOL INC | New Orleans | — | $8.6M | 3 |
| PRIORITY HEALTH CARE INC | Marrero | E70 Health Care | $8.5M | 7 |
| POWER COALITION FOR EQUITY AND JUSTICE | New Orleans | R01 Civil Rights, Social Action & Advocacy | $8.5M | 3 |
| Helix Network of Educational Choices | Baton Rouge | B29 Education | $8.4M | 0 |
| COMMUNITY LEADERS ADVOCATING STUDENT | New Orleans | B29 Education | $8.4M | 1 |
| YWCA OF GREATER BATON ROUGE | Baton Rouge | P27Z Human Services | $8.4M | 2 |
| CHRISTIAN ACRES YOUTH CENTER INC | Tallulah | N20 Recreation & Sports | $8.4M | 2 |
| LOUISIANA STATE BAR ASSOCIATION | New Orleans | — | $8.3M | 8 |
| EMPLOYMENT DEVELOPMENT SERVICES INC | Baton Rouge | J30Z Employment | $8.3M | 1 |
| Institute of Women & Ethnic Studies | New Orleans | V21Z Social Science | $8.2M | 5 |
| ARGENT FOUNDATION | Ruston | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $8.2M | 0 |
| THE LIGHTHOUSE FOR THE BLIND IN | New Orleans | G41Z Diseases, Disorders & Medical Disciplines | $8.2M | 4 |
| LIFE HOUSE | Gonzales | S20 Community Improvement & Capacity Building | $8.2M | 1 |
| PELICAN EDUCATIONAL FOUNDATION INC | Baton Rouge | B200 Education | $8.1M | 1 |
