| HADDIS MINISTRIES | Easley | P30 Human Services | $443k | 0 |
| WHITE HORSE MISSIONS | Fountain Inn | X20 Religion-Related | $443k | 1 |
| STEPPING STONES MINISTRY INC | Columbia | J32 Employment | $442k | 5 |
| THE MARSHALL MILLER FOUNDATION | Hilton Head Island | T22Z Philanthropy, Voluntarism & Grantmaking Foundations | $442k | 0 |
| SENIOR HOUSING AND RESOURCE MANAGEMENT | Charleston | E60 Health Care | $442k | 2 |
| OSPREY VILLAGE THRIFT STORES LLC | Hilton Head Island | T12 Philanthropy, Voluntarism & Grantmaking Foundations | $442k | 0 |
| ANIMAL SHELTER OF CLARENDON COUNTY INC | Manning | D20 Animal-Related | $441k | 1 |
| SOUTH CAROLINA RAILROAD MUSEUM INC | Columbia | — | $440k | 0 |
| THE PHARMACEUTICAL COMPLIANCE | Myrtle Beach | S41 Community Improvement & Capacity Building | $439k | 0 |
| THE LOT PROJECT | Anderson | X99 Religion-Related | $439k | 1 |
| COMMUNITY FIRST LAND TRUST | Charleston | L20 Housing & Shelter | $439k | 1 |
| FAMILY PROMISE OF THE MIDLANDS INC | Columbia | P85 Human Services | $439k | 1 |
| ORANGEBURG AREA BOYS AND GIRLS CLUB | Orangeburg | — | $438k | 0 |
| SUMTER COUNTY DEVELOPMENTAL | Sumter | P82Z Human Services | $437k | 0 |
| Congaree Rapid FC | West Columbia | — | $437k | 0 |
| AHEPA 242 INC | Greenville | L20 Housing & Shelter | $437k | 0 |
| CAROLINA DANCE COLLABORATIVE | Greenville | A62 Arts, Culture & Humanities | $437k | 2 |
| GAMMA PHI BETA SORORITY INC | Columbia | — | $436k | 0 |
| FINE ARTS CENTER PARTNERS | Greenville | A60 Arts, Culture & Humanities | $436k | 0 |
| THE SUNSHINE FOUNDATION INC | Barnwell | T20Z Philanthropy, Voluntarism & Grantmaking Foundations | $436k | 0 |
| SCANSOURCE CHARITABLE FOUNDATION | Greenville | P20Z Human Services | $436k | 0 |
| CHAMBER MUSIC CHARLESTON | Charleston | A6B Arts, Culture & Humanities | $436k | 1 |
| CHRISTIAN HOPE ACADEMY INC | Gaston | B20 Education | $435k | 1 |
| Bel-Aire Community Partners | Greenville | B82 Education | $435k | 1 |
| BEACH UNITED FOOTBALL CLUB | Myrtle Beach | O50 Youth Development | $435k | 0 |
| TIDELANDS COMMUNITY HOSPICE FOUNDATION | Georgetown | P74 Human Services | $434k | 2 |
| CAROLINA WILDLIFE CARE INC | Columbia | D340 Animal-Related | $434k | 0 |
| BROWNS CREEK WATER CO INC | Union | W80 Public & Societal Benefit | $434k | 3 |
| DEFENDERS FOR CHILDREN | Greenville | F99 Mental Health & Crisis Intervention | $434k | 1 |
| The Jacobs Family Charitable Foundation | Hilton Head Island | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $433k | 0 |
| THE PAUL AND MARGARET PORTER | Fort Mill | — | $433k | 0 |
| INTERNATIONAL FASHION JEWELRY ACCESSORY GROUP INC | Little River | S41 Community Improvement & Capacity Building | $433k | 0 |
| Harmony School | Columbia | — | $433k | 0 |
| RICHLAND LIBRARY FRIENDS AND FOUNDATION | Columbia | B117 Education | $433k | 1 |
| Therapy Resource Group | Fort Mill | B01 Education | $432k | 0 |
| CITY OF SPARTANBURG DEVELOPMENT | Spartanburg | — | $432k | 0 |
| SOUTH CAROLINA FIRST STEPS TO | Greenwood | — | $432k | 1 |
| MIDLANDS EDUCATION & BUSINESS | West Columbia | J20 Employment | $431k | 1 |
| UMOJA VILLAGE | Aiken | P01 Human Services | $431k | 7 |
| CAMPING MINISTRIES OF THE CAROLINAS | Waterloo | X20 Religion-Related | $431k | 0 |
| AIKEN PREGNANCY CARE CENTER INC | Aiken | E400 Health Care | $431k | 6 |
| United Farmers USA Inc | Manning | B90 Education | $430k | 0 |
| THE ASSOCIATION OF SOUTHEASTERN | Newberry | Z99 Unknown | $429k | 0 |
| LANCASTER COUNTY COUNCIL OF THE ARTS | Lancaster | A26Z Arts, Culture & Humanities | $428k | 2 |
| WESTERN UPSTATE ASSOCIATION OF REALTORS | Anderson | — | $428k | 1 |
| HUMANE SOCIETY OF MARLBORO COUNTY INC | Bennettsville | D20 Animal-Related | $427k | 0 |
| PROJECT GOLF | North Myrtle Beach | N6A Recreation & Sports | $427k | 0 |
| JOE'S WISH | West Columbia | P60 Human Services | $427k | 0 |
| Go Love | York | Q32 International, Foreign Affairs & National Security | $427k | 2 |
| BARRINEAU PUBLIC UTILITY INC | Lake City | — | $427k | 0 |
