| HEARTGIFT FOUNDATION | Austin | G43 Diseases, Disorders & Medical Disciplines | $5.4M | 1 |
| Southeast Education Foundation dba Legacy Christian Academy | Beaumont | B25 Education | $5.4M | 1 |
| DIOCESAN MIGRANT & REFUGEE SERVICES INC | El Paso | — | $5.4M | 1 |
| BARBARA BUSH HOUSTON LITERACY FOUNDATION | Houston | T11 Philanthropy, Voluntarism & Grantmaking Foundations | $5.3M | 4 |
| REVELATION MEDIA INC | Richardson | X80 Religion-Related | $5.3M | 0 |
| GREATER SATX | San Antonio | — | $5.3M | 9 |
| THE MENNINGER CLINIC FOUNDATION | Houston | E110 Health Care | $5.3M | 2 |
| PROJECTHANDUP | Grapevine | L40 Housing & Shelter | $5.3M | 3 |
| Hollywood Memorial Park Co | Houston | — | $5.3M | 13 |
| THE MIRACLE FOUNDATION INC | Austin | P31 Human Services | $5.3M | 8 |
| THE ELECTION CENTER | Katy | B99M Education | $5.3M | 6 |
| Astros Golf Foundation | Houston | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $5.3M | 3 |
| TUA THE BUTLER FAMILY FOUNDATION | Dallas | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $5.3M | 1 |
| YOUNG MEN'S CHRISTIAN ASSOCIATION OF THE GOLDEN CRESCENT INC | Victoria | P27Z Human Services | $5.3M | 0 |
| INT'L ASSOC OF FIRE FIGHTERS LOCAL 341 | Houston | — | $5.3M | 0 |
| SKY RANCH HORN CREEK | Van | X20 Religion-Related | $5.3M | 0 |
| LIVE OAK CLASSICAL SCHOOL | Waco | B20 Education | $5.3M | 2 |
| CH WILKINSON PHYSICIAN NETWORK | Irving | — | $5.3M | 21 |
| INTERNATIONAL ALLIANCE OF THEATRICAL STAGE EMPLOYEES LOCAL 51 | Houston | — | $5.3M | 6 |
| CHILDRENS ADVOCACY CENTER OF SMITH COUNTY | Tyler | I72 Crime & Legal-Related | $5.3M | 1 |
| The Winston School | Dallas | — | $5.3M | 6 |
| FORM COMMUNITIES INC | San Antonio | F70 Mental Health & Crisis Intervention | $5.3M | 2 |
| THE BURKE FOUNDATION INC | Driftwood | — | $5.3M | 1 |
| AFGE AFL-CIO COUNCIL 083 NATIONAL BORDER PATROL COUNCIL | Edinburg | J40 Employment | $5.3M | 17 |
| Frederic J & Dorothea Oppenheimer Foundation | San Antonio | — | $5.3M | 0 |
| THE CONCILIO | Dallas | P84Z Human Services | $5.3M | 3 |
| MISSION MUTUAL | Arlington | Q33 International, Foreign Affairs & National Security | $5.3M | 7 |
| Brazos Valley Council on Alcohol and Substance Abuse | Bryan | F21Z Mental Health & Crisis Intervention | $5.3M | 2 |
| Curtis C Gunn Inc Welfare Benefit Trust | San Antonio | — | $5.3M | 5 |
| HOPE CLINIC OF GARLAND INC | Garland | E70 Health Care | $5.3M | 2 |
| SKYLY INC | The Woodlands | R24 Civil Rights, Social Action & Advocacy | $5.3M | 0 |
| Texas Chemistry Council Inc | Austin | — | $5.2M | 6 |
| EnerGeo Alliance | Houston | — | $5.2M | 7 |
| Cullen Trust For Health Care | Houston | E120 Health Care | $5.2M | 1 |
| TRUSTED WORLD FOUNDATION INC | Garland | P19 Human Services | $5.2M | 1 |
| INTERNATIONAL NEWS MEDIA ASSOCIATION INC | Dallas | — | $5.2M | 2 |
| Stages | Houston | A610 Arts, Culture & Humanities | $5.2M | 2 |
| CIS CONFERENCE INC | Sherman | W90 Public & Societal Benefit | $5.2M | 4 |
| SCOTTISH RITE EDUCATIONAL ASSOCIATION OF TEXAS | Austin | Y40Z Mutual & Membership Benefit | $5.2M | 2 |
| FOOD CARE CENTER | Killeen | — | $5.2M | 0 |
| Center for Success & Independence Inc | Houston | F33 Mental Health & Crisis Intervention | $5.2M | 0 |
| National Association for the Self-Employed Inc | Frisco | — | $5.2M | 10 |
| HOUSING CHANNEL | Fort Worth | L20Z Housing & Shelter | $5.2M | 1 |
| TEXAS ASSOCIATION FOR THE EDUCATION OF YOUNG CHILDREN | Austin | B19 Education | $5.2M | 2 |
| HERALDS OF THE GOSPEL FOUNDATION INC | Houston | Q12 International, Foreign Affairs & National Security | $5.2M | 0 |
| BEAT AIDS COALITION TRUST | San Antonio | — | $5.2M | 4 |
| Spay-Neuter Assistance Program Inc | Houston | D200 Animal-Related | $5.2M | 4 |
| CAROLYN AND DAVID BROOKS FAMILY FOUNDATION | McKinney | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $5.2M | 0 |
| TEXAS INTERNATIONAL PRODUCE ASSOC | Mission | — | $5.2M | 0 |
| TurningPoint Foundation | Dallas | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $5.2M | 0 |
