| Presbyterian Healthcare Services | Albuquerque | E210 Health Care | $2.4B | 42 |
| St Vincent Hospital | Santa Fe | E220 Health Care | $569.8M | 16 |
| SAN JUAN REGIONAL MEDICAL CENTER | Farmington | E220 Health Care | $364M | 13 |
| OTERO COUNTY HOSPITAL ASSOCIATION | Alamogordo | E220 Health Care | $250.8M | 15 |
| Sacramento Mountains Foundation Inc | Alamogordo | R20 Civil Rights, Social Action & Advocacy | $246.7M | 10 |
| TRICORE LABORATORY SERVICES CORP | Albuquerque | E192 Health Care | $128.1M | 11 |
| ROADRUNNER FOOD BANK INC | Albuquerque | K31Z Food, Agriculture & Nutrition | $126.1M | 8 |
| PRESBYTERIAN MEDICAL SERVICES | Santa Fe | E300 Health Care | $125.8M | 10 |
| LOVELACE BIOMEDICAL RESEARCH INSTITUTE | Albuquerque | H920 Medical Research | $112.1M | 9 |
| LEA COUNTY ELECTRIC COOPERATIVE INC | Lovington | — | $110.6M | 15 |
| TAOS HEALTH SYSTEMS INC | Taos | E21Z Health Care | $94.6M | 9 |
| DELTA DENTAL PLAN OF NEW MEXICO INC | Albuquerque | — | $74.6M | 17 |
| DEL NORTE CREDIT UNION | Los Alamos | — | $73.9M | 17 |
| ARTESIA GENERAL HOSPITAL | Artesia | E20 Health Care | $73.6M | 9 |
| CENTRAL VALLEY ELECTRIC COOPERATIVE INC | Artesia | — | $72M | 14 |
| Rehoboth McKinley Christian Healthcare | Gallup | E22 Health Care | $70.4M | 11 |
| CONTINENTAL DIVIDE ELECTRIC COOPERATIVE | Grants | — | $69.6M | 16 |
| TRICORE INC | Albuquerque | E60 Health Care | $68.2M | 11 |
| UNIVERSITY OF NEW MEXICO FOUNDATION INC | Albuquerque | B110 Education | $68.1M | 14 |
| SOUTHWEST CARE CENTER | Santa Fe | — | $65.8M | 10 |
| KIT CARSON ELECTRIC COOPERATIVE INC | Taos | — | $61.7M | 18 |
| NAVAJO TECHNICAL UNIVERSITY | Crownpoint | — | $61.6M | 6 |
| CREDIT UNIONS IN THE STATE OF NEW M | Albuquerque | — | $61.3M | 7 |
| LA CLINICA DE FAMILIA INC | Las Cruces | E39Z Health Care | $59.2M | 9 |
| STATE EMPLOYEES CREDIT UNION | Santa Fe | — | $58.4M | 12 |
| JEMEZ MOUNTAINS ELECTRIC COOPERATIVE | Espanola | — | $56.4M | 19 |
| BEN ARCHER HEALTH CENTER | Hatch | E320 Health Care | $53.6M | 5 |
| CIBOLA GENERAL HOSPITAL | Grants | E22 Health Care | $47.5M | 8 |
| HOSANNA | Albuquerque | X200 Religion-Related | $46.3M | 10 |
| FARMERS ELECTRIC COOPERATIVE INC | Clovis | — | $42.6M | 15 |
| ARCA | Albuquerque | P80 Human Services | $42M | 2 |
| CENTRAL NEW MEXICO ELECTRIC COOPERATIVE | Mountainair | — | $40.1M | 16 |
| ADELANTE DEVELOPMENT CENTER INC | Albuquerque | J33Z Employment | $40M | 9 |
| Southwest Multicraft | Albuquerque | — | $39.3M | 0 |
| INSTITUTE OF AMERICAN INDIAN ARTS & ALASKA NATIVE | Santa Fe | B420 Education | $38.9M | 17 |
| OTERO COUNTY ELECTRIC COOPERATIVE INC | Cloudcroft | — | $37.5M | 18 |
| GOODWILL INDUSTRIES OF NEW MEXICO | Albuquerque | J32Z Employment | $37.5M | 5 |
| UNITED WAY OF SOUTHWEST NM INC | Las Cruces | T70Z Philanthropy, Voluntarism & Grantmaking Foundations | $36.9M | 1 |
| BERNALILLO COUNTY HEALTH CARE CORP | Albuquerque | — | $36.8M | 10 |
| CENTRAL TEXAS HEALTH AND BENEFIT PLAN | Albuquerque | Y42 Mutual & Membership Benefit | $36.4M | 0 |
| RAMAH NAVAJO SCHOOL BOARD INC | Pine Hill | B200 Education | $35.9M | 13 |
| THE SANTA FE OPERA | Santa Fe | A6A Arts, Culture & Humanities | $35.1M | 8 |
| ALBUQUERQUE ACADEMY | Albuquerque | B250 Education | $34.4M | 8 |
| THE ARMAND HAMMER UNITED WORLD | Montezuma | B420 Education | $34.4M | 9 |
| FIRST CHOICE COMMUNITY HEALTHCARE | Albuquerque | E32Z Health Care | $32.7M | 6 |
| YOUTH DEVELOPMENT INC | Albuquerque | P700 Human Services | $32M | 6 |
| ALAMO NAVAJO SCHOOL BOARD INC | Alamo | S20 Community Improvement & Capacity Building | $31.4M | 10 |
| SMALL BUSINESS INVESTMENT | Tijeras | S30 Community Improvement & Capacity Building | $31M | 1 |
| HOMEWISE INC | Santa Fe | — | $30.5M | 12 |
| Santa Fe Indian School | Santa Fe | B25Z Education | $29.6M | 20 |
